Composition Abciximab (10mg)
Rx Prescription Required
Pack vial of 5 ml Injection
Storage Store in a refrigerator (2 – 8ยฐC). Do not freeze.
Chemical Class Amino acids, Peptides analogues
Action Class Glycoprotein IIb/IIIa inhibitors
Habbit Forming No
Manufacturer Reliance Life Sciences
Manufacturer address Dhirubhai Ambani Life Sciences Centre, R-282, TTC Area of MIDC, Thane-Belapur Road, Rabale, Navi Mumbai 400 701

Abcixirel 10mg Injection
Abcixirel 10mg Injection belongs to a group of medicines called antiplatelet medicines or blood thinners. It prevents the clotting of blood in the heart during, before, or after an angioplasty (procedure to improve blood flow to the heart).
Basic Info
Description
Abcixirel 10mg Injection is administered under the supervision of a doctor. Your doctor will decide the dose and duration of the medicine for you. You should continue all your other medicines that are advised by the doctor for your long-term treatment even after this injection.
Use of this medicine may cause low blood platelets and increase your risk of bleeding. Let your doctor know immediately if you see pinpoint rash or blood in your vomits, urine, or stool. Your doctor will explain the benefits and risks associated with this medicine before it is administered.
This medicine is used with caution for some people. Thus, you must inform the doctor if you are suffering from any bleeding disorder, kidney or liver disease. Also, let your doctor know if you are pregnant or breastfeeding and about all the other medications that you are taking regularly.
Uses
Prevention of Blood clots
How To Use
Your doctor or nurse will give you this medicine. Kindly do not self administer.
MOA
Abcixirel 10mg Injection is an antiplatelet medication. It works by preventing the platelets from sticking together, thereby decreasing the formation of harmful blood clots.
What If
If you miss a dose of Abcixirel 10mg Injection, please consult your doctor.
Drug Tips
It is usually given by your nurse or doctor as an infusion (drip) into a vein.
It increases your risk of bleeding. Be careful while shaving, cutting fingernails or toenails or using sharp objects.
Notify your doctor if you see blood in your vomit, urine or stool (black, tarry stools or bright red blood).
Faqs
Q. Can the use of Abcixirel 10mg Injection increase the risk of bleeding?
Yes, Abcixirel 10mg Injection increases the risk of bleeding. Always be careful while doing activities that may cause an injury or bleeding. Tell your doctor immediately if you notice any abnormal bruising or bleeding.
Q. What medicines should I avoid while taking Abcixirel 10mg Injection?
Abcixirel 10mg Injection can interact with several medicines. Do not take any medicine without talking to your doctor.
Q. When will I feel better after taking Abcixirel 10mg Injection?
Abcixirel 10mg Injection reduces your risk of developing blood clots in the blood vessels of your leg, lungs, heart and brain. You may not feel any difference after taking Abcixirel 10mg Injection. However, keep taking this medicine as prescribed by your doctor because you will still be getting its full benefits.
Benifits
In Prevention of Blood clots
Abcixirel 10mg Injection prevents new blood clots from forming and prevents the existing ones from getting bigger. It works by blocking a substance in the body which is involved in blood clotting. Thus it helps your blood flow smoothly throughout the body. This can help reduce damage caused by clots in your lungs (pulmonary embolism), brain (stroke), heart (heart attack), or other blood vessels (thrombosis).It can also be used to prevent clots from forming after surgery, for example, to replace a knee or hip joint. Although it does not โdissolveโ blood clots, it can prevent them from getting bigger so your body can dissolve them over time. It can also make it less likely that parts of a clot will break off and travel to other parts of the body.
Side Effects
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if youโre worried about them
Low blood platelets
Bleeding
Safety Profile
Alcohol:CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Abcixirel 10mg Injection. Please consult your doctor.
Pregnancy:CONSULT YOUR DOCTOR
Abcixirel 10mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding:SAFE IF PRESCRIBED
Abcixirel 10mg Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving:NOT RELEVANT
Not relevant, as Abcixirel 10mg Injection is intended for use in hospitalised patients.
Kidney:CAUTION
Abcixirel 10mg Injection should be used with caution in patients with kidney disease. Dose adjustment of Abcixirel 10mg Injection may be needed. Please consult your doctor.Use of Abcixirel 10mg Injection is not recommended in patients with severe kidney disease.
Liver:CAUTION
Abcixirel 10mg Injection should be used with caution in patients with liver disease. Dose adjustment of Abcixirel 10mg Injection may be needed. Please consult your doctor.Use of Abcixirel 10mg Injection is not recommended in patients with severe liver disease.
Refferences
Weitz JI. Blood Coagulation and Anticoagulant, Fibrinolytic, and Antiplatelet Drugs. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilmanโs: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 870-71
Zehnder JL. Drugs Used in Disorders of Coagulation. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 599.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 3-4.
Fox KA, White HD, Gersh BJ, et al. Antithrombotic Agents: Platelete Inhibitors, Acute Anticoagulants, Fibrinolytics, and Chronic Anticoagulants. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. pp. 354-355.
Abciximab. Leiden, The Netherlands: Centocor B.V.; 1997. view
Drugs and Lactation Database. Bethesda : National Library of Medicine ; 2006. Abciximab. . view
Central Drugs Standard Control Organisation . Abciximab. view

