Abitac 1% Ointment

Composition Tacrolimus (1% w/w)
Rx Prescription Required
Pack tube of 10 gm Ointment
Storage Store below 30°C
Chemical Class Macrolide Lactams
Action Class Immunosuppressant- Calcineurin inhibitors
Habbit Forming No
Manufacturer Abigail Care Pharmaceutical
Manufacturer address Plot No. 160, First Floor, Industrial Area Phase – 2, Panchkula – 134 113 (Haryana)

Abitac 1% Ointment is used to treat eczema (atopic dermatitis). It works by suppressing the activity of certain immune cells that cause inflammation (redness and swelling) of the skin. This relieves itching and improves rashes in atopic dermatitis.

Abitac 1% Ointment is used for external use. It should be used 2-4 times a day on the affected area or use it as suggested by the doctor. It should be applied slowly and evenly to the skin until it is rubbed in. You should not use it too often and you should not cover the treated area with a bandage or plaster. You must inform your doctor if there’s no improvement even after two weeks of treatment or if the skin gets worse.It is a safe medicine with few side effects, but you may get an application site reaction like burning, irritation, itching, and redness. This medicine is not normally recommended during pregnancy or while breastfeeding unless it is clearly needed.

Prevention of organ rejection in transplant patients

This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and gently massage the ointment.

Abitac 1% Ointment is an immunosuppressant. It works by suppressing the activity of certain immune cells that cause inflammation (redness and swelling) of the skin. This relieves itching and improves rashes in atopic dermatitis.

If you miss a dose of Abitac 1% Ointment, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Abitac 1% Ointment is effective at treating eczema (atopic dermatitis) when other treatment options have failed.

It works by decreasing itching, redness, and skin rashes.

Apply thinly, to affected areas of skin only. Clean the affected area and dry well before applying Abitac 1% Ointment. Avoid contact with water after application.

Inform your doctor if there’s no improvement even after two weeks of treatment, or if the skin gets worse.

Don’t cover the area being treated with airtight dressings such as bandages unless directed by a doctor, as this may increase the risk of side effects.

Stop using Abitac 1% Ointment and consult your doctor if your eczema becomes infected.

Continuous long-term use of the ointment should be avoided. Use as prescribed by you doctor.

Q. What is Abitac 1% Ointment used for?

Abitac 1% Ointment is a medicine that modulates the immune system. It works on the immune system and mostly decreases its activity. It is used to treat moderate to severe eczema (atopic dermatitis) in adults who do not respond to steroids or develop side effects on using them. In atopic dermatitis, the skin’s immune system undergoes an overreaction and causes skin inflammation leading to itchiness, redness and dryness. Abitac 1% Ointment acts on the abnormal immune response and alters it, thereby relieving the skin inflammation and itchiness.

Q. What are the side effects of Abitac 1% Ointment?

Abitac 1% Ointment, when applied to the skin, may cause skin irritation, burning sensation and itching at the site of application. These are usually mild to moderate in severity and normally resolve within one week of starting the treatment. Redness is also a common manifestation along with sensation of warmth, pain, altered sensation and rash at the site of application. Using it increases the patients’ increased risk of getting inflamed or infected hair follicles, cold sores, acne and generalized herpes simplex infections.

Q. Is Abitac 1% Ointment ointment safe?

As compared to other immune-suppressing medicines, Abitac 1% Ointment has been found to be a safe and effective short-term treatment for atopic dermatitis. When applied on the affected part of the skin, its absorption to the blood and body is minimal. Hence, the side effects are less as compared to when taken through oral route.

Q. Does Abitac 1% Ointment has abuse potential?

No, Abitac 1% Ointment does not have abuse potential and thus, is not a controlled substance. Controlled substances have potential for abuse so they need permission by authorities and doctor for use.

Q. Does Abitac 1% Ointment cause cancer?

Long-term use of Abitac 1% Ointment has been found to have increased risk of lymph node tumors called lymphoma. Some studies have found that few patients who used Abitac 1% Ointment ointment or another similar medication developed skin cancer or lymphoma. Consult your doctor if you have to use Abitac 1% Ointment ointment for more than 6 weeks or if your eczema symptoms have not improved or are getting worse with time during your treatment.

Q. Is Abitac 1% Ointment a steroid?

No, Abitac 1% Ointment is not a steroid. It is a medicine which modulates the working of the immune system. It is used in the treatment of eczema, most commonly in atopic dermatitis. An advantage of Abitac 1% Ointment is that it does not cause skin thinning (atrophy) or other steroid-related side effects.

In Prevention of organ rejection in transplant patients

Abitac 1% Ointment belongs to a group of medicines known as immunosuppressants. Organ rejection happens when your immune system treats the new organ as an invader and attacks it. This medicine weakens your immune response (which usually fights infection) and reduces the chance of your body attacking the transplanted organ. It is used in combination with other medicines to make it much more likely that your transplant operation will be successful. You should continue taking the medicine and should not stop it until your doctor says so.

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Stomach pain

Nausea

Liver damage

Kidney damage

Increased thirst

Increased glucose level in blood

Diarrhea

Application site reactions (burning, irritation, itching and redness)

Alcohol:

No interaction found/established

Pregnancy:CONSULT YOUR DOCTOR

Abitac 1% Ointment may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding:SAFE IF PRESCRIBED

Abitac 1% Ointment is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Driving:

No interaction found/established

Kidney:

No interaction found/established

Liver:

No interaction found/established

Burkhart C, Morrell D, Goldsmith L. Dermatological Pharmacology. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1822.

Lake DF, Briggs AD, Akporiaye ET. Immunopharmacology. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 972.

Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1305-309.

Tacrolimus monohydrate. Hurley, Berkshire: Leo Laboratories Limited; 2002 . view

Central Drugs Standard Control Organisation . view