Abitate 250mg Powder for Injection is used in the treatment of cancer of the prostate gland. It may be also used to treat other conditions, as determined by the doctor. It is sometimes used with certain other medicines as part of combination chemotherapy.
Abitate 250mg Powder for Injection is given as an injection under the supervision of a doctor, do not self administer the injection. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include vomiting, decreased potassium level in blood, edema (swelling), decreased white blood cell count, fatigue and increased liver enzymes. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. Other than this, yellowing of skin, loss of appetite, shortness of breath, dark urine and nausea can happen, which indicate some liver problem. Your doctor might check you for liver function, blood pressure, and the level of potassium in your blood.
Before taking it, tell your doctor if have high blood pressure, heart problem, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. It may harm your baby. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. You may be asked for regular monitoring of blood glucose level while on treatment.
Prostate cancer
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Abitate 250mg Powder for Injection is an anticancer medication. It works by preventing androgen (male hormone) production in man. This is done by inhibiting an enzyme (CYP17) that is responsible for the production of androgen. This is how it slows down the growth of prostate cancer.
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Abitate 250mg Powder for Injection treats prostate cancer that has spread to other parts of the body.
It is usually taken with another medicine called prednisolone to reduce unwanted side effects.
It must be taken on an empty stomach. Don’t eat any food for at least 2 hours before or 1 hour after your dose.
Always use effective birth control measures to prevent pregnancy while taking this medicine.
Your doctor may regularly monitor your liver function, blood pressure, and the level of potassium in your blood while you are having treatment with this medicine.
Q. Can Abitate 250mg Powder for Injection cure prostate cancer?
Abitate 250mg Powder for Injection does not cure cancer but helps in prolonging and improving the life of the patient. Moreover, when prostate cancer is treated with Abitate 250mg Powder for Injection then the frequency of fractures is relatively less. Similarly, the increase in pain is less common with Abitate 250mg Powder for Injection.
Q. Is Abitate 250mg Powder for Injection a chemotherapy drug?
Abitate 250mg Powder for Injection is a hormonal treatment not a chemotherapy drug. It is used to treat prostate cancer in adult men that has spread to other parts of the body. Abitate 250mg Powder for Injection stops your body from making testosterone. This can slow down the growth of prostate cancer.
Q. Why do I need to take prednisolone with Abitate 250mg Powder for Injection?
Your doctor will always prescribe prednisolone with Abitate 250mg Powder for Injection. Taking these two medicines together lowers the risk of getting high blood pressure, fluid retention (having too much water in your body), or having reduced levels of potassium in your blood, which can occur due to Abitate 250mg Powder for Injection.
Q. Does Abitate 250mg Powder for Injection affect liver?
Abitate 250mg Powder for Injection can cause severe liver problems. In very rare cases, Abitate 250mg Powder for Injection may even cause failure of the liver to function (called acute liver failure), which can even lead to death. Tell your doctor if you experience yellowing of the skin or eyes, darkening of the urine, or severe nausea or vomiting, as these could be signs or symptoms of liver problems.
Q. How frequently should the liver investigations be done?
Liver enzymes should be measured prior to starting the treatment, every two weeks for the first three months into the treatment, and monthly thereafter. If you develop clinical symptoms or signs suggestive of liver toxicity, liver enzymes should be measured immediately. If the liver enzyme levels are increased beyond certain levels, your doctor may temporarily discontinue the treatment with Abitate 250mg Powder for Injection.
In Prostate cancer
Prostate gland is a small walnut-sized gland that produces a fluid called seminal fluid that nourishes and transports sperms in males. The most common symptom of prostate cancer is difficulty with urination, but sometimes there are no symptoms at all. Abitate 250mg Powder for Injection decreases or stops the growth of cancer cells by decreasing the amount of testosterone (natural hormone in males) in men. This also relieves difficulty in passing urine and makes it easier for you to urinate.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Altered blood sugar level
Increased levels of blood fat
Joint swelling
Hypercholesterolemia (high cholesterol)
Cough
High blood pressure
Diarrhea
Urinary tract infection
Anemia (low number of red blood cells)
Increased liver enzymes
Fatigue
Decreased white blood cell count
Decreased potassium level in blood
Vomiting
Edema (swelling)
Alcohol:CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Abitate 250mg Powder for Injection. Please consult your doctor.
Pregnancy:UNSAFE
Abitate 250mg Powder for Injection is highly unsafe to use during pregnancy. Seek your doctor’s advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Breast feeding:UNSAFE
Abitate 250mg Powder for Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving:SAFE
Abitate 250mg Powder for Injection does not usually affect your ability to drive.
Kidney:SAFE IF PRESCRIBED
Abitate 250mg Powder for Injection is safe to use in patients with kidney disease. No dose adjustment of Abitate 250mg Powder for Injection is recommended.Because of the limited information, cautious use of Abitate 250mg Powder for Injection is recommended in patients with severe kidney disease.
Liver:CAUTION
Abitate 250mg Powder for Injection should be used with caution in patients with liver disease. Dose adjustment of Abitate 250mg Powder for Injection may be needed. Please consult your doctor.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 4-5.
Chemocare. Abiraterone Acetate. view
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