Accentrix Solution for Injection

Composition Ranibizumab (10mg/ml)
Rx Prescription Required
Pack vial of 1 Solution for Injection
Storage Store in a refrigerator (2 – 8°C). Do not freeze.
Chemical Class Monoclonal antibody (mAb)
Action Class Vascular endothelial growth factor (VEGF) inhibitor for AMD
Habbit Forming No
Manufacturer Novartis India Ltd
Manufacturer address Sandoz House, Shiv Sagar Estate, Worli Mumbai -400 018, India

Accentrix Solution for Injection is administered directly into the eyeball by an eye specialist. You should not self administer this medicine at home. The common side effects include conjunctival hemorrhage, eye pain, eye floaters, increased intraocular pressure, and eye inflammation.

However, if you experience these side effects for a longer duration or any other symptoms which you think may be due to this medicine, please inform your doctor. It is not advised to drive after administration of this injection as it may cause blurring of vision.

Diabetic eye disease
Wet age-related macular degeneration
Macular edema due to retinal vein occlusion

Your doctor or nurse will guide you how to use this medicine.

Accentrix Solution for Injection is an anti-angiogenic medication. It works by blocking a protein called vascular endothelial growth factor (VEGF). This stops the growth and leakage of abnormal blood vessels in the eye(s) that may cause vision loss.

If you miss a dose of Accentrix Solution for Injection, please consult your doctor.

Accentrix Solution for Injection is used for the treatment of eye diseases caused by diabetes, macular degeneration and macular swelling.

It is administered directly into the eyeball by an eye specialist.

It may cause temporary visual disturbances. Don’t drive or do anything that requires mental focus until you know how Accentrix Solution for Injection affects you.

Inform your doctor if you experience increased eye pain and redness, blurred or decreased vision, or increased sensitivity to light.

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In Diabetic eye disease

Diabetic eye disease is a group of eye problems seen in people with diabetes. It can lead to vision loss, weak eyesight or even blindness. Accentrix Solution for Injection helps prevent this damage caused by diabetes and stops the worsening of vision. Consult your doctor if you have any doubts.

In Wet age-related macular degeneration

Macula is the part of the retina responsible for central vision. Wet age-related macular degeneration is an eye disorder that causes blurred vision or a blind spot in your visual field due to abnormal blood vessels that leak fluid or blood into the macula. This leads to vision problems. Accentrix Solution for Injection helps prevent leakage of such abnormal blood vessels and therefore prevents vision loss. It is given as an injection by a doctor or nurse and should not be self-administered.

In Macular edema due to retinal vein occlusion

Retinal vein occlusion is a blockage of the small veins that carry blood away from the retina, which is that part of the eye that is responsible for vision. So, retinal vein occlusion often causes permanent damage to the retina and loss of vision. It can also lead to other eye problems. Sometimes there is a complete loss of vision almost immediately. Accentrix Solution for Injection helps treat swelling of the macula that can cause vision disturbances. show moreshow less

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Eye inflammation

Increased intraocular pressure

Eye floaters

Eye pain

Conjunctival hemorrhage

Alcohol:CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Accentrix Solution for Injection. Please consult your doctor.

Pregnancy:CONSULT YOUR DOCTOR

Accentrix Solution for Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding:SAFE IF PRESCRIBED

Accentrix Solution for Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Driving:UNSAFE

Accentrix Solution for Injection may cause blurring of your vision for a short time just after its use. Do not drive until your vision is clear.

Kidney:SAFE IF PRESCRIBED

Accentrix Solution for Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Accentrix Solution for Injection may not be needed in these patients. Please consult your doctor.

Liver:SAFE IF PRESCRIBED

Accentrix Solution for Injection is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Accentrix Solution for Injection may not be needed in these patients. Please consult your doctor.

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Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1196-97.

Lake DF, Briggs AD, Akporiaye ET. Immunopharmacology. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 977.

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