Composition Acenocoumarol (2mg)
Rx Prescription Required
Pack strip of 30 tablets
Storage Store below 30ยฐC
Chemical Class 4-hydroxycoumarin Derivative
Action Class Vitamin K Antagonists
Habbit Forming
Manufacturer Zeelab Pharmacy Pvt Ltd
Manufacturer address 913, D-Mall,Netaji Subhash Place Pitampura New Delhi New Delhi DL 110034 IN

Acimalone 2 Tablet
Acimalone 2 Tablet is an oral anticoagulant that helps prevent harmful blood clots in the legs, lungs, brain, and heart. It is used for deep vein thrombosis, pulmonary embolism, and stroke prevention.
Basic Info
Description
Acimalone 2 Tablet is an oral anticoagulant that helps prevent harmful blood clots in the legs, lungs, brain, and heart. It is used for deep vein thrombosis, pulmonary embolism, and stroke prevention.
Acimalone 2 Tablet should be taken as advised by the doctor. You may take it with or without food, but it is better to take it at a fixed time. This medicine should not be stopped abruptly without consulting the doctor. You should take this medicine regularly to get the most benefit, even if you feel fine. It prevents future harm.
The most common side effect of Acimalone 2 Tablet is bleeding. Let your doctor know immediately if you see a pinpoint rash or blood in your vomit, urine, or stool. If you are going under any surgery or dental treatment, you may need to stop this medicine for some time, but only after consulting with your doctor.
Before taking Acimalone 2 Tablet, you must inform the doctor if you are suffering from any kidney or liver disease or taking any medicine, including supplements and herbal products. Also, let your doctor know if you are pregnant or breastfeeding and about all the other medications that you are taking regularly.
Uses
Deep vein thrombosis
Blood clots
Pulmonary embolism
Stroke prevention
How To Use
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Acimalone 2 Tablet may be taken with or without food, but it is better to take it at a fixed time.
MOA
Acimalone 2 Tablet works by slowing down the body’s ability to form blood clots. It does this by blocking the action of vitamin K, which is essential for making clotting proteins in the liver. By reducing these clotting proteins, Acimalone 2 Tablet thins the blood, making it less likely for harmful clots to form.
What If
Q: What if you forget to take Acimalone Tablet?
A: If you miss a dose of Acimalone 2 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Drug Tips
Avoid making sudden major changes to your diet during treatment with this medicine.
Acimalone 2 Tablet increases your risk of bleeding. Be careful while shaving, cutting fingernails or toenails, using sharp objects, or engaging in contact sports (e.g., football, wrestling).
Notify your doctor if you see blood in your vomit, urine, or stool (black, tarry stools or bright red blood).
Do not consume alcohol while taking Acimalone 2 Tablet, as this may increase its side effects.
If you are going to have a surgery or dental treatment, you may be asked to stop taking Acimalone 2 Tablet temporarily.
Do not discontinue use without consulting your doctor, as this may increase your chances of having another heart attack or stroke.
Your doctor may get regular blood tests done to make sure Acimalone 2 Tablet is working properly.
Faqs
Q. How long do I need to take Acimalone 2 Tablet?
You should continue taking Acimalone 2 Tablet for as long as recommended by your doctor. Depending upon the condition you are being treated for, you may have to take it for several months or years or maybe for the rest of your life.
Q. What should I avoid while taking Acimalone 2 Tablet?
You should avoid alcohol while taking Acimalone 2 Tablet as alcohol may interfere with working of Acimalone 2 Tablet. In addition to that, avoid cranberry juice or other cranberry products as there may be a risk of enhanced blood thinning. Avoid breastfeeding or getting pregnant as it may harm your child.
Q. Do I need to stop Acimalone 2 Tablet if I have to undergo a surgery?
Depending on the type of surgery that is to be performed, your doctor will tell you whether to continue or stop Acimalone 2 Tablet. It will be decided by your doctor after weighing the risks and benefits of discontinuing Acimalone 2 Tablet.
Q. Is Acimalone 2 Tablet same as warfarin?
Both Acimalone 2 Tablet and warfarin are blood thinners, but they have some differences. Warfarin has a more stable blood thinning effect.
Q. How long does it take for Acimalone 2 Tablet to start working?
It takes a little longer for Acimalone 2 Tablet to start working. On an average, it may take 2-3 days for Acimalone 2 Tablet to show its blood-thinning effect. For these 2-3 days, heparin may be used and then discontinued.
Q. What if I forget to take a dose?
If you forget to take a dose of Acimalone 2 Tablet, take it as soon as you remember. However, if it is time for your next dose then skip the missed dose. Do not double the dose and continue your normal schedule. Keep a diary or set a reminder, so that you do not forget it often.
Q. What monitoring is required while taking Acimalone 2 Tablet?
The bleeding times should be carefully monitored from 2nd or 3rd dose of Acimalone 2 Tablet and till the clotting status is stabilized. Thereafter, the bleeding time can be monitored monthly. This frequency may be more in elderly.
Benifits
Side Effects
Hemorrhage
Safety Profile
Alcohol:UNSAFE
It is unsafe to consume alcohol with Acimalone 2 Tablet.
Pregnancy:UNSAFE
Acimalone 2 Tablet is highly unsafe to use during pregnancy. Seek your doctor’s advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Breast feeding:SAFE IF PRESCRIBED
Acimalone 2 Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Driving:SAFE
Acimalone 2 Tablet does not usually affect your ability to drive.
Kidney:CAUTION
Acimalone 2 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Acimalone 2 Tablet may be needed. Please consult your doctor.Use of Acimalone 2 Tablet is not recommended in patients with severe kidney disease.
Liver:CAUTION
Acimalone 2 Tablet should be used with caution in patients with liver disease. Dose adjustment of Acimalone 2 Tablet may be needed. Please consult your doctor.Use of Acimalone 2 Tablet is not recommended in patients with severe liver disease.
Refferences
Weitz JI. Blood Coagulation and Anticoagulant, Fibrinolytic, and Antiplatelet Drugs. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilmanโs: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 865-71.
Acenocoumarol [EMC SmPC]. Luxembourg: Merus Labs Luxco II S.ร R.L.; 2025. [Accessed 03 May 2025] (online) Available from: View
Castellano JM, Narayan RL, Vaishnava P, et al. Anticoagulation during pregnancy in patients with a prosthetic heart valve. Nat Rev Cardiol. 2012;9(7):415-24. [Accessed 14 Mar. 2019] (online) Available from: View
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Acenocoumarol. [Updated 2020 Jan 20]. [Accessed 19 Feb. 2020] (online) Available from: View
Acenocoumarol [Package Leaflet]. Madrid, Spain: Rovi Pharma Industrial Services, S.A.,; 2025. [Accessed 03 May 2025] (online) Available from: View
Acenocoumarol [Prescribing Information]. Montreal, Quebec: Paladin Labs Inc.; 2009. [Accessed 03 May 2025] (online) Available from: View

