Actigrain P 40mg/10mg Capsule SR is a combination of two medicines that helps in preventing migraine. This medicine is not used for treatment of acute migraine attack.
Actigrain P 40mg/10mg Capsule SR should be taken on empty stomach, but try to have it same time regularly at a fixed time preferably at night. The dose and how often you take it depends on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. You should take this medicine for as long as it is prescribed for you. Lifestyle modifications like avoiding stress, smoking, and processed food items may help this medicine work better.
Few common side effects of this medicine include weight gain, slow heart rate, tiredness, depression, drowsiness and cold extremities. It may cause sleepiness so try not to drive or do anything that requires mental focus or rise slowly while from sitting position. The drug has the ability to hide the symptoms of the blood sugar level, hence monitor your blood sugar level regularly as well as blood pressure while taking this medicine.
Before taking this medicine, let your doctor know if you have liver or kidney, or depression disease, or if you are pregnant or breastfeeding. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works.
Prevention of Migraine
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Actigrain P 40mg/10mg Capsule SR is to be taken empty stomach.
Actigrain P 40mg/10mg Capsule SR is a combination of two medicines: Propranolol and Flunarizine, which prevents migraine. Propranolol is a beta blocker and Flunarizine is a calcium channel blocker. They work by stabilizing the reactive nerve cells and increasing the threshold to migraine activation. They also inhibit cortical spreading depression (CSD- electric waves that move across the brain and cause pain and inflammation).
If you miss a dose of Actigrain P 40mg/10mg Capsule SR, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
You have been prescribed Actigrain P 40mg/10mg Capsule SR for prevention of migraine headaches.
Do not take it to treat an acute attack of migraine.
Some tips that may help avoid a migraine attack:Have your meals at the same time everydayAvoid bright lights and extreme temperaturesAvoid loud music and noisy placesAvoid chocolates, cheese, processed food, alcohol and smokingGet sufficient sleep and avoid stress
Have your meals at the same time everyday
Avoid bright lights and extreme temperatures
Avoid loud music and noisy places
Avoid chocolates, cheese, processed food, alcohol and smoking
Get sufficient sleep and avoid stress
It should be taken at night-time before going to bed.
It may cause sleepiness. Don’t drive or do anything that requires mental focus until you know how Actigrain P 40mg/10mg Capsule SR affects you.
keep taking it regularly every day, even if you don’t have any symptoms.
Q. In which conditions is the use of Actigrain P 40mg/10mg Capsule SR contraindicated?
Use of Actigrain P 40mg/10mg Capsule SR is considered to be harmful for patients with allergy to any of the ingredients or excipients of this medicine. This medicine contains propranolol, so its use should be avoided in patients with asthma, slow heart rate, abnormal heart rhythms, or heart conditions like AV block or sick sinus syndrome. Since this medicine also contains flunarizine, the use of this medicine should be avoided in patients with the history of depression or Parkinson’s disease.
Q. What are the instructions for the storage and disposal of Actigrain P 40mg/10mg Capsule SR?
Keep Actigrain P 40mg/10mg Capsule SR in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
Q. Can I stop taking Actigrain P 40mg/10mg Capsule SR when my symptoms are improved?
Actigrain P 40mg/10mg Capsule SR is given as a prophylactic treatment for the prevention of migraine headaches. Do not stop taking this medicine until advised by your doctor as it may cause your migraine episodes to return. This medicine contains propranolol and a sudden withdrawal of propranolol may cause sweating, shaking, irregular or fast heartbeat, worsening of underlying angina or heart attack. You must take Actigrain P 40mg/10mg Capsule SR exactly as advised by your doctor.
Q. Can Actigrain P 40mg/10mg Capsule SR be used for the treatment of a migraine headache?
No, Actigrain P 40mg/10mg Capsule SR does not help in relieving a migraine headache that has already started. It can only be used for preventing any new episode of migraine headaches.
In Prevention of Migraine
Actigrain P 40mg/10mg Capsule SR helps improve the flow of blood in your brain and prevents abnormal activity of muscles that triggers migraines. It is a very effective medicine for preventing migraine attacks, however, it does not treat an attack that has already started. By preventing and reducing the frequency migraine attacks, the medicine can help you carry out your daily activities and improve your quality of life.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Cold extremities
Abnormal dreams
Drowsiness
Depression
Tiredness
Slow heart rate
Weight gain
Alcohol:UNSAFE
It is unsafe to consume alcohol with Actigrain P 40mg/10mg Capsule SR.
Pregnancy:CONSULT YOUR DOCTOR
Actigrain P 40mg/10mg Capsule SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding:CONSULT YOUR DOCTOR
Information regarding the use of Actigrain P 40mg/10mg Capsule SR during breastfeeding is not available. Please consult your doctor.
Driving:UNSAFE
Actigrain P 40mg/10mg Capsule SR may cause side effects which could affect your ability to drive.Actigrain P 40mg/10mg Capsule SR may cause visual disturbances, hallucinations, fatigue, mental confusion, dizziness or tiredness. This may affect your driving ability.
Kidney:SAFE IF PRESCRIBED
Actigrain P 40mg/10mg Capsule SR is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Actigrain P 40mg/10mg Capsule SR may not be needed in these patients. Please consult your doctor.
Liver:CAUTION
Actigrain P 40mg/10mg Capsule SR should be used with caution in patients with liver disease. Dose adjustment of Actigrain P 40mg/10mg Capsule SR may be needed. Please consult your doctor.Regular monitoring of blood pressure is advisable for dose adjustment.
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