Actorise 60 Injection

Composition Darbepoetin alfa (60mcg)
Rx Prescription Required
Pack prefilled syringe of 0.3 ml Injection
Storage Store in a refrigerator (2 – 8°C). Do not freeze.
Chemical Class Amino Acids, Peptides Analogues
Action Class Erythropoiesis-stimulating agent (ESA)
Habbit Forming No
Manufacturer Cipla Ltd
Manufacturer address Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013

Actorise 60 Injection is a medicine that needs to be used with utmost care because it can lead to serious side effects. It is important that you seek treatment from a doctor who is experienced in providing this medical therapy. You should follow all the directions of the doctor strictly. It is given under the supervision of a healthcare professional.

It may cause side effects like high blood pressure and hypersensitivity. Inform your doctor if there are symptoms of very high blood pressure such as severe headache, problems with your eyesight, nausea, vomiting, or fits (seizures).

Your doctor may get your blood tests done regularly to monitor the levels of salts (electrolytes such as potassium), hemoglobin, and blood cells in your blood. You should stop taking it and consult with a doctor if you develop shortness of breath or skin rash.

Treatment of Anemia due to chronic kidney disease
Treatment of Anemia due to cancer chemotherapy

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Actorise 60 Injection is an erythropoiesis-stimulating agent (ESA). It works by stimulating the bone marrow (soft tissue inside the bones which produces red blood cells) to produce more red blood cells.

If you miss a dose of Actorise 60 Injection, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Actorise 60 Injection helps in the treatment of anemia that may have occurred due to chronic kidney disease or cancer chemotherapy.

It is given as a single injection under your skin.

Your doctor may get your blood tests done regularly to monitor the levels of hemoglobin, blood cells and electrolytes such as potassium in your blood.

Stop taking Actorise 60 Injection and inform your doctor if you develop shortness of breath or skin rash.

Q. How long does it take for Actorise 60 Injection to start working?

You will be able to notice an increase in the count of red blood cells (hemoglobin levels) in 2-6 weeks of starting Actorise 60 Injection. If you have any other concerns, consult your doctor.

Q. Is Actorise 60 Injection safe to use?

Actorise 60 Injection is a medicine that needs to be used with utmost care because it can lead to serious side effects and even death of the patient. It is important that you seek treatment from a doctor who is experienced in providing Actorise 60 Injection therapy. Follow all the directions strictly.

Q. Other than PRCA, can there be other reasons for not responding to Actorise 60 Injection?

You may not respond to Actorise 60 Injection if you have deficiencies of iron, folic acid or vitamin B12. It is important that you take measures to correct these deficiencies. Other reasons behind not responding to the treatment could be bleeding, infections, inflammation and bone marrow fibrosis. Therefore, consult our doctor regarding the same.

Q. Can Actorise 60 Injection be used in children?

Yes, Actorise 60 Injection is used to treat anemia due to chronic kidney disease in children who are above 1 year of age. The effectiveness of Actorise 60 Injection and side effects seen in children are similar to adults. However, consult your doctor if you are not sure.

Q. Can Actorise 60 Injection affect blood pressure?

Yes, Actorise 60 Injection can affect blood pressure. During initial therapy with Actorise 60 Injection, blood pressure should be monitored and those who have high blood pressure should take appropriate measures to control blood pressure. Your doctor may stop Actorise 60 Injection if the blood pressure remains uncontrolled.

In Treatment of Anemia due to chronic kidney disease

Anemia is a condition where your body does not have enough red blood cells to carry oxygen around your body. Chronic kidney disease (CKD) refers to the loss of normal kidney function over a long span of time. CKD progresses gradually over a few years but may become permanent if left untreated. CKD can lead to anemia. Actorise 60 Injection can boost your levels of red blood cells and reduce the symptoms of anemia such as tiredness and weakness. Taking this injection improves the quality of life.

In Treatment of Anemia due to cancer chemotherapy

Low red blood cell count is termed as anemia. Cancer treatment with chemotherapy often causes many side effects, one of the major ones being anemia. Actorise 60 Injection stimulates the production of red blood cells in bone marrow and regulates the haemoglobin in the blood. This treats anemia in cancer patients receiving chemotherapy.show moreshow less

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Hypersensitivity

High blood pressure

Alcohol:CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Actorise 60 Injection. Please consult your doctor.

Pregnancy:CONSULT YOUR DOCTOR

Actorise 60 Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding:SAFE IF PRESCRIBED

Actorise 60 Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Driving:SAFE

Actorise 60 Injection does not usually affect your ability to drive.

Kidney:SAFE IF PRESCRIBED

Actorise 60 Injection is safe to use in patients with kidney disease. No dose adjustment of Actorise 60 Injection is recommended.

Liver:CAUTION

Actorise 60 Injection should be used with caution in patients with liver disease. Dose adjustment of Actorise 60 Injection may be needed. Please consult your doctor.

Kaushansky K, Kipps TJ. Hematopoietic Agents: Growth Factors, Minerals, and Vitamins. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1071-72.

Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 358-59.

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Darbepoetin alfa. Milton Road, Cambridge: Amgen Ltd.; 2001 . view

Darbepoetin alfa. Thousand Oaks, CA: Amgen Inc.; 2001. view