Composition Cyclophosphamide (50mg)
Rx Prescription Required
Pack strip of 10 tablets
Storage Store in a refrigerator (2 – 8°C). Do not freeze.
Chemical Class Nitrogen Mustard Compounds
Action Class Alkylating Agents
Habbit Forming
Manufacturer Adley Formulations
Manufacturer address Adley Formulation, SCO- 42, Sector 12, Panchkula-134112, Haryana, India
Cyclophosphamide (50mg)
PRIMARY PRODUCT
VIEW AVAILABLE SUBSTITUTES
Adcyclo Tablet
Adcyclo Tablet is used in the treatment of different kinds of cancers. It is also used to treat kidney disease known as nephrotic syndrome in children after other treatments have not worked. It may be also used to treat other conditions, as determined by the doctor.
Basic Info
Description
Adcyclo Tablet is used in the treatment of different kinds of cancers. It is also used to treat kidney disease known as nephrotic syndrome in children after other treatments have not worked. It may be also used to treat other conditions, as determined by the doctor.
Adcyclo Tablet should be taken with food preferably in morning but at the same time every day to get the most benefit. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include vomiting, nausea, hair loss, fever, and blood in urine. If they do not go away or get worse, tell your doctor. There may be ways of preventing or reducing these effects. It is very strong medicine and some people may develop serious side effects while taking it. This medicine may lower your ability to fight infections and lead to problems with your blood, liver or kidneys. Your doctor will advise you regular blood tests to check for these. It is advised that you drink extra fluids so that you pass more urine. This will help prevent bladder and kidney problems and keep your kidneys working well.
Before taking it, tell your doctor if you have liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. It may harm your baby. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Uses
Cancer
Nephrotic syndrome
How To Use
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Adcyclo Tablet is to be taken with food.
MOA
Adcyclo Tablet is an anti-cancer medication. It is an alkylating agent which works by damaging the genetic material (DNA and RNA) of the cancer cells, thereby stopping their growth and multiplication. This is how it works against cancer.
What If
Q: What if you forget to take this medicine?
A:
Drug Tips
Adcyclo Tablet helps in the treatment of cancer.
Drink plenty of fluids or urinate frequently to prevent urinary problems while taking this medication.
Take it with food if you experience irritation of the stomach, preferably in the morning.
Your doctor may get regular blood tests to monitor your blood counts while on treatment with this medication.
You are more likely to get sick or heal slower while taking this medication. Talk to your doctor before getting any vaccines.
Contact your doctor immediately if you experience difficulty in urinating or blood in urine while on treatment with this medication.
Do not take Adcyclo Tablet if you are pregnant or breastfeeding.
Use effective contraception method to prevent pregnancy while taking this medicine.
Adcyclo Tablet helps in the treatment of cancer.
Drink plenty of fluids or urinate frequently to prevent urinary problems while taking this medication.
Take it with food if you experience irritation of the stomach, preferably in the morning.
Your doctor may get regular blood tests to monitor your blood counts while on treatment with this medication.
You are more likely to get sick or heal slower while taking this medication. Talk to your doctor before getting any vaccines.
Contact your doctor immediately if you experience difficulty in urinating or blood in urine while on treatment with this medication.
Do not take Adcyclo Tablet if you are pregnant or breastfeeding.
Use effective contraception method to prevent pregnancy while taking this medicine.
Faqs
Q. Can Adcyclo Tablet cause infertility?
Yes, Adcyclo Tablet can cause infertility in both men and women. It may interfere with the normal menstrual cycle in women and may stop sperm production in men. If you are considering becoming parents after the treatment please discuss this with your doctor. Talk to your doctor about cryopreservation (freezing) of sperm or eggs prior to treatment because of the possibility of irreversible infertility due to therapy with Adcyclo Tablet.
Q. Do I need to avoid sun exposure during treatment with Adcyclo Tablet?
No, there is no evidence that you need to avoid sun exposure while on Adcyclo Tablet. Skin and nail discoloration are reported rarely with Adcyclo Tablet.
Q. Can Adcyclo Tablet cause cancer?
Cancer medicines and radiation therapy can increase the risk of developing other cancers. These may not develop soon and may take a number of years after the completion of your treatment. The risk of developing cancer with Adcyclo Tablet is high in the urinary bladder. Other rare cancers that may occur with use of Adcyclo Tablet include Acute leukemia, Myelodysplastic syndrome, and cancer of the ureters.
Q. Is Adcyclo Tablet chemotherapy medicine?
Yes, Adcyclo Tablet is a chemotherapy medicine, it belongs to the class of alkylating agents. It works by killing cancer cells. It is also known as cytotoxic medicine.
Q. Can Adcyclo Tablet be used for non-cancer condition?
Yes, Adcyclo Tablet can be used to treat nephrotic syndrome (a disease that is caused by damage to the kidneys) in children whose disease has not improved, has gotten worse, or has come back after taking other medications. Along with that, it can be used in children who experienced intolerable side effects with other medications. However, in adults, the safety and effectiveness of Adcyclo Tablet for nephrotic syndrome has not been established.
Q. Can Adcyclo Tablet causes weight loss?
Yes, Adcyclo Tablet may cause weight loss because of reduced appetite. This reduction in weight could be due to underlying cancer. Consult your doctor, if weight loss is worrying you.
Q. Can Adcyclo Tablet cause infertility?
Yes, Adcyclo Tablet can cause infertility in both men and women. It may interfere with the normal menstrual cycle in women and may stop sperm production in men. If you are considering becoming parents after the treatment please discuss this with your doctor. Talk to your doctor about cryopreservation (freezing) of sperm or eggs prior to treatment because of the possibility of irreversible infertility due to therapy with Adcyclo Tablet.
Q. Do I need to avoid sun exposure during treatment with Adcyclo Tablet?
No, there is no evidence that you need to avoid sun exposure while on Adcyclo Tablet. Skin and nail discoloration are reported rarely with Adcyclo Tablet.
Q. Can Adcyclo Tablet cause cancer?
Cancer medicines and radiation therapy can increase the risk of developing other cancers. These may not develop soon and may take a number of years after the completion of your treatment. The risk of developing cancer with Adcyclo Tablet is high in the urinary bladder. Other rare cancers that may occur with use of Adcyclo Tablet include Acute leukemia, Myelodysplastic syndrome, and cancer of the ureters.
Q. Is Adcyclo Tablet chemotherapy medicine?
Yes, Adcyclo Tablet is a chemotherapy medicine, it belongs to the class of alkylating agents. It works by killing cancer cells. It is also known as cytotoxic medicine.
Q. Can Adcyclo Tablet be used for non-cancer condition?
Yes, Adcyclo Tablet can be used to treat nephrotic syndrome (a disease that is caused by damage to the kidneys) in children whose disease has not improved, has gotten worse, or has come back after taking other medications. Along with that, it can be used in children who experienced intolerable side effects with other medications. However, in adults, the safety and effectiveness of Adcyclo Tablet for nephrotic syndrome has not been established.
Q. Can Adcyclo Tablet causes weight loss?
Yes, Adcyclo Tablet may cause weight loss because of reduced appetite. This reduction in weight could be due to underlying cancer. Consult your doctor, if weight loss is worrying you.
Benifits
Side Effects
Hair loss
Nausea
Infection
Diarrhea
Vomiting
Decreased white blood cell count (neutrophils)
Decreased white blood cell count (lymphocytes)
Myelosuppression
Cystitis
Microhematuria
Safety Profile
Alcohol:UNSAFE
It is unsafe to consume alcohol with Adcyclo Tablet.
Pregnancy:CONSULT YOUR DOCTOR
Adcyclo Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding:UNSAFE
Adcyclo Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving:UNSAFE
Adcyclo Tablet may cause side effects which could affect your ability to drive.Adcyclo Tablet may cause undesirable effects (e.g., dizziness, blurred vision, visual impairment) which could affect the ability to drive.
Kidney:CAUTION
Adcyclo Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Adcyclo Tablet may be needed. Please consult your doctor.
Liver:CAUTION
Adcyclo Tablet should be used with caution in patients with liver disease. Dose adjustment of Adcyclo Tablet may be needed. Please consult your doctor.
Refferences
Lake DF, Briggs AD, Akporiaye ET. Immunopharmacology. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 975.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 335-38.
Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 26 Mar. 2019] (online) Available from: View
Cyclophosphamide monohydrate. Norfolk, UK: Baxter Healthcare Ltd.; 2004 [revised 9 Dec. 2016]. [Accessed 26 Mar. 2019] (online) Available from: View
