Adfil 6mg Injection

Composition Pegfilgrastim (6mg)
Rx Prescription Required
Pack prefilled syringe of 0.6 ml Injection
Storage Store in a refrigerator (2 – 8°C). Do not freeze.
Chemical Class Granulocyte Colony-Stimulating Factor
Action Class Granulocyte-colony stimulating factor (G-CSF)
Habbit Forming No
Manufacturer Adley Formulations
Manufacturer address Adley Formulation, SCO- 42, Sector 12, Panchkula-134112, Haryana, India

Adfil 6mg Injection is given as an injection by a qualified medical professional. You should continue to take as long as your doctor advises for it. The duration of treatment varies according to your need and response to treatment. You might be asked for regular tests done to check the number of blood cells in your blood and your bone density level while you are taking this medicine.

The most common side effects of this medicine include bone pain, joint pain, headache, nausea, and muscle pain. Other than this, pain or redness at the site of injection is common. But, inform your doctor if you notice a lump, swelling, or bruising that does not go away. It might not prevent you from all kinds of infection, hence inform your doctor if you notice fever, chills, shortness of breath, sore throat, and swelling around the face or neck.

Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. You must avoid driving or attention-seeking activity if you experience dizziness after taking this medicine.

Prevention of Infections after chemotherapy

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Adfil 6mg Injection is a growth factor that stimulates the bone marrow to produce white blood cells. These cells protect the body against infections.

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If you miss a dose of Adfil 6mg Injection, please consult your doctor.

Adfil 6mg Injection reduces the risk of infection in people treated with chemotherapy.

It is usually given as a daily injection into the tissue just under the skin or into the vein. 

You will normally receive your first dose at least 24 hours after your chemotherapy or bone marrow transplant.

Store it in the refrigerator, protect it from light, and don’t shake it.

For a more comfortable injection, leave the syringe at room temperature for 30 minutes before using it.

Pain or redness in the area of injection is common. Let your doctor know if you notice a lump, swelling, or bruising that doesn’t go away.

Use caution while driving or doing anything that requires concentration as Adfil 6mg Injection may cause dizziness.

Your doctor may get regular tests done to monitor the number of blood cells in your blood, and your bone density level while you are receiving treatment with this medicine.

Stop taking Adfil 6mg Injection and inform your doctor if you have a fever, shortness of breath, fast rate of breathing or trouble breathing.

Q. What is Adfil 6mg Injection? How is it given?

Adfil 6mg Injection belongs to a class of medications called colony stimulating factors. It helps reduce the chances of infections and side effects related to chemotherapy and does not directly treat cancer. It comes as a solution (liquid) to inject subcutaneously (under the skin), 24 hours after chemotherapy. It may be injected by a doctor/nurse in a hospital or you may be shown how to use injections at home

Q. How does pegfilgrastim work?

Pegfilgrastim belongs to a class of medications called colony stimulating factors. It acts on hematopoietic cells (cells in the bone marrow that produce red blood cells, white blood cells, and platelets) to increase production of neutrophils (a type of white blood cell) in the body.

In Prevention of Infections after chemotherapy

Adfil 6mg Injection increases the production of white blood cells by stimulating the immune system in our body. White blood cells are those cells that help us to fight infections. This medicine is really effective and must be used under medical supervision. Avoid being in crowds and wash your hands often to prevent any infections. Have plenty of fluids, unless otherwise advised by the doctor not to.

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Injection site pain

Pain in extremity

Back pain

Muscle pain

Low blood platelets

Nausea

Headache

Joint pain

Bone pain

Alcohol:CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Adfil 6mg Injection. Please consult your doctor.

Pregnancy:CONSULT YOUR DOCTOR

Adfil 6mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding:SAFE IF PRESCRIBED

Adfil 6mg Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Driving:SAFE

Adfil 6mg Injection does not usually affect your ability to drive.

Kidney:SAFE IF PRESCRIBED

Adfil 6mg Injection is safe to use in patients with kidney disease. No dose adjustment of Adfil 6mg Injection is recommended.

Liver:CONSULT YOUR DOCTOR

There is limited information available on the use of Adfil 6mg Injection in patients with liver disease. Please consult your doctor.

Masters SB. Agents Used in Anemias; Hematopoetic Growth Factors. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 581.

Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1074-75.

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