Adpaxil 260mg/43.4ml Injection

Composition Paclitaxel (6mg/ml)
Rx Prescription Required
Pack vial of 43.4 ml Injection
Storage Store below 30°C
Chemical Class Taxanes Derivatives
Action Class Antimicrotubule agents- Taxanes
Habbit Forming
Manufacturer Adley Formulations
Manufacturer address Adley Formulation, SCO- 42, Sector 12, Panchkula-134112, Haryana, India

Adpaxil 260mg/43.4ml Injection is an anti-cancer medication used for the treatment of breast cancer, pancreatic cancer and non-small cell lung cancer.

It is given as an injection by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Some common side effects of this medicine include nausea, vomiting, and weakness. It may also cause serious side effects such as swelling of hands, lips, hair loss, and weight gain. To reduce these side effects your doctor may suggest some medication along with it. But, inform your doctor if you notice unexplained bruising or bleeding, sore throat, mouth ulcers, high temperature (fever). This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells and liver function.

Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Breast cancer

Non-small cell lung cancer

Pancreatic cancer

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Adpaxil 260mg/43.4ml Injection is an anticancer medication. It works by interfering with the microtubule structures which help the cancer cells to divide and multiply. This slows the growth of cancer cells and eventually kills them.

Q: What if you forget to take this medicine?
A:

Adpaxil 260mg/43.4ml Injection is an anti-cancer medication used for the treatment of breast cancer, pancreatic cancer, and non-small cell lung cancer.

It is given as an intravenous (IV) injection into your vein, usually over 1 hour and every three weeks.

Do not take Adpaxil 260mg/43.4ml Injection if you are pregnant or breastfeeding. Use reliable methods of contraception to prevent pregnancy while taking this medicine.

Your doctor may get regular blood tests done to monitor your blood cells and liver function during treatment with this medicine.

Inform your doctor if you notice unexplained bruising or bleeding, sore throat, mouth ulcers, high temperature (fever) or other signs of infection.

Talk to your doctor if you have sudden weight gain or if you have swelling in your arms and legs that doesn’t go away.

Q. Is Adpaxil 260mg/43.4ml Injection generic/ taxane/ FDA approved/cytotoxic?

Yes, Adpaxil 260mg/43.4ml Injection is generic/ taxane/ FDA approved/ cytotoxic

Q. Is Adpaxil 260mg/43.4ml Injection a vesicant?

Adpaxil 260mg/43.4ml Injection is usually a vesicant (irritant)

Q. Is Adpaxil 260mg/43.4ml Injection light sensitive/ hydrophobic/ cardiotoxic?

Yes, Adpaxil 260mg/43.4ml Injection is light sensitive/ hydrophobic/ cardiotoxic

Q. Does Adpaxil 260mg/43.4ml Injection cause hair loss?

Yes, Adpaxil 260mg/43.4ml Injection may cause hair loss as a side effect. Please inform your doctor about any side effect while you are on Adpaxil 260mg/43.4ml Injection therapy

Q. What is Adpaxil 260mg/43.4ml Injection derived from?

Adpaxil 260mg/43.4ml Injection is derived from bark of the Pacific yew, Taxus brevifolia.

In Breast cancer

Adpaxil 260mg/43.4ml Injection helps to treat breast cancer and it may be used alone or in combination with other medicines or treatment modalities like chemotherapy. It relieves the symptoms of breast cancer such as breast lumps, bloody discharge from nipples or changes in the shape or texture of the breast. Adpaxil 260mg/43.4ml Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. Discuss with your doctor if any of the side effects bother you.

Nausea

Vomiting

Weakness

Low blood platelets

Rash

Upper respiratory tract infection

Urinary tract infection

Bleeding

Anemia (low number of red blood cells)

Flushing (sense of warmth in the face, ears, neck and trunk)

Hair loss

Decreased blood pressure

Peripheral neuropathy (tingling and numbness of feet and hand)

Diarrhea

Decreased white blood cell count (neutrophils)

Alcohol:UNSAFE

It is unsafe to consume alcohol with Adpaxil 260mg/43.4ml Injection.

Pregnancy:CONSULT YOUR DOCTOR

Adpaxil 260mg/43.4ml Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding:UNSAFE

Adpaxil 260mg/43.4ml Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving:UNSAFE

Adpaxil 260mg/43.4ml Injection may cause side effects which could affect your ability to drive.As there is no reason why you cannot continue driving between courses of Adpaxil 260mg/43.4ml Injection but you should remember that this medicine contains some alcohol and it may be unwise to drive

Kidney:SAFE IF PRESCRIBED

Adpaxil 260mg/43.4ml Injection is safe to use in patients with kidney disease. No dose adjustment of Adpaxil 260mg/43.4ml Injection is recommended.However, talk to your doctor if you have any underlying kidney disease.

Liver:CAUTION

Adpaxil 260mg/43.4ml Injection should be used with caution in patients with liver disease. Dose adjustment of Adpaxil 260mg/43.4ml Injection may be needed. Please consult your doctor.Use of Adpaxil 260mg/43.4ml Injection is not recommended in patients with severe liver disease.

Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1707-709.
Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 949.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1044-46.
Paclitaxel. Hurley, Maidenhead: Hospira UK Ltd.; 2005 [revised Dec. 2016]. [Accessed 24 Jan. 2019] (online) Available from: View
Paclitaxel. Summit, New Jersey: Celgene Corporation; 2005 [revised Oct. 2012]. [Accessed 26 Mar. 2019] (online) Available from: View
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Paclitaxel. [Updated 2020 Jan 20]. [Accessed 18 Feb. 2020] (online) Available from: View