Advent 400mg/57mg Tablet DT

Treatment of Resistant Tuberculosis (TB)

Treatment of Bacterial infections

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Montu 10mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

Advent 400mg/57mg Tablet DT is an antibiotic. It has two active agents, amoxycillin and clavulanic acid. Amoxycillin works by preventing the formation of the bacterial protective covering (cell wall) essential for the survival of the bacteria. Whereas, clavulanic acid serves a special purpose of inhibiting an enzyme (beta-lactamase) that is produced by resistant bacteria. This makes the combination of amoxycillin and clavulanic acid an effective line of treatment for many types of infections.

Q: What if I forget to give Advent 400mg/57mg Tablet DT to my child?
A: You can give the missed dose as soon as you remember unless advised otherwise by the doctor. Skip the missed dose if it is almost time for the next dose. Do not give a double dose to catch up and follow the prescribed dosing schedule.

Your child must complete the entire course of antibiotics. Stopping too soon may cause the bacteria to multiply again, become resistant, or cause another infection.

Your child may have a bitter taste in the mouth after the intake of Advent 400mg/57mg Tablet DT. Eating citrus fruit or sipping plenty of water or fruit juice may help.

Encourage your child to drink plenty of water in case diarrhea develops as a side effect.

Never give Advent 400mg/57mg Tablet DT until and unless prescribed by the doctor. You must also never share your child’s medicine with anyone else even if they show similar symptoms.

Do not give Advent 400mg/57mg Tablet DT to treat common cold and flu-like symptoms caused by viruses.

Never save medicine for future illnesses. It cannot be said whether the same medicine will work on future infections.

Check ‘expiry’ before giving Advent 400mg/57mg Tablet DT to your child. Immediately discard all the expired medicines.

Stop Advent 400mg/57mg Tablet DT immediately if your child develops an itchy rash, facial swelling, or breathing difficulty. Report to the doctor without any delay.

Q. Can other medicines be given at the same time as Advent 400mg/57mg Tablet DT?

Advent 400mg/57mg Tablet DT can sometimes interact with other medicines or substances. Tell your doctor about any other medicines your child is taking before starting Advent 400mg/57mg Tablet DT. Also, check with your child’s doctor before giving any medicine to your child.

Q. Can I get my child vaccinated while on treatment with Advent 400mg/57mg Tablet DT?

Antibiotics usually do not interfere with the ingredients in vaccines or cause a bad reaction in a child who has just been vaccinated. However, children taking antibiotics should not get vaccinated until they recover from the illness. As soon as your child feels better, the vaccine can be given.

Q. Which lab tests may my child undergo while taking Advent 400mg/57mg Tablet DT on a long-term basis?

With prolonged therapy, the doctor may monitor kidney and liver function tests periodically to keep a check on your child’s condition.

Q. Can I give a higher than the recommended dose of Advent 400mg/57mg Tablet DT to my child?

No, giving a higher than recommended dose of this medicine can increase the risks of side effects. If your child experiences increased severity of symptoms, please consult your doctor for re-evaluation.

Q. Can I stop giving Advent 400mg/57mg Tablet DT to my child when the symptoms are relieved?

No, do not stop giving this medicine to your child unless the full course of the treatment is complete, even if you feel better. The symptoms may improve before the infection is completely cured. Hence, continue giving the medicine for the due course as it may still be showing beneficial effects.

Q. Can the use of Advent 400mg/57mg Tablet DT cause diarrhea?

Yes, Advent 400mg/57mg Tablet DT may cause diarrhea. It is an antibiotic that kills harmful bacteria. In addition to that, the medicine may also affect the helpful bacteria in your child’s stomach and cause diarrhea. In case of diarrhea, encourage your child to drink plenty of water or other fluids. Talk to your doctor if diarrhea persists and you notice any signs of dehydration, like less frequency of urination with dark colored and strong-smelling urine. Do not give any other medicine to your child without consulting a doctor.

Q. Do all viral common colds result in secondary bacterial infection?

Most of the time, bacterial infections do not follow viral infections. In fact, giving antibiotics in viral infection can increase your child’s risk of developing side effects. So, use antibiotics only after consulting with your child’s doctor.

Q. The mucus coming out of my child’s nose is yellow-green. Is it a sign of a bacterial infection?

Yellow or green mucus in the nose does not mean that antibiotics are needed. During a common cold, it is normal for mucus to thicken up and change from clear to yellow or green. Symptoms often last for 7-10 days.

Q. Is there any sign which shows that my child needs immediate medical attention?

You must call your child’s doctor right away if your child experiences serious allergic reactions (breathing problems, skin rashes), gastrointestinal infections (diarrhea), and liver damage (weakness, paleness, vomiting). Though rare, these side effects are serious and need an expert’s attention.

In Treatment of Resistant Tuberculosis (TB)

In multidrug-resistant (MDR) tuberculosis, the causative bacteria produce an enzyme called beta-lactamase. This enzyme breaks down the antibiotics and makes them ineffective. As a result, the bacteria become resistant to the antibiotic being used for treatment. Advent 400mg/57mg Tablet DT comprises two active ingredients, amoxycillin and clavulanic acid. While clavulanic acid stops the enzyme from rendering amoxycillin ineffective, amoxycillin works towards killing the tuberculosis-causing bacteria. This makes the combination of amoxycillin and clavulanic acid an effective treatment for resistant tuberculosis.

Abdominal pain

Allergy

Vomiting

Nausea

Diarrhea

Mucocutaneous candidiasis

Kidney:CAUTION

Advent 400mg/57mg Tablet DT should be used with caution in patients with kidney disease. Dose adjustment of Advent 400mg/57mg Tablet DT may be needed. Please consult your doctor.

Liver:CAUTION

Advent 400mg/57mg Tablet DT should be used with caution in patients with liver disease. Dose adjustment of Advent 400mg/57mg Tablet DT may be needed. Please consult your doctor.Consult with your child’s doctor before giving Advent 400mg/57mg Tablet DT to your child in case of a severe form of liver disease.

National Health Service. Co-amoxiclav. [Accesses 13 Jan. 2021] (online) Available from: View