Alcarb 450 Injection is used in the treatment of ovarian cancer and small cell lung cancer. It shows its working by stopping or slowing down the growth of cancer cells.
Alcarb 450 Injection is given as an injection into veins under the supervision of a doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Nausea, vomiting, fatigue, and increased liver enzyme are some common side effects of this medicine. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections or bleeding. Inform your doctor if you notice fever, sore throat, chills, unusual bleeding or bruising, and dark urine. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels.
You must inform your doctor if you experience allergic reactions with injection such as skin rash, itching, and trouble breathing. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Ovarian cancer
Small cell lung cancer
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Alcarb 450 Injection is an anti-cancer medication. It works by damaging the genetic material (DNA and RNA) of the cancer cells which stops their growth and multiplication.
If you miss a dose of Alcarb 450 Injection, please consult your doctor.
It is given as an injection into the veins under the supervision of a doctor.
Q. Is Alcarb 450 Injection cell cycle specific?
No, Alcarb 450 Injection is not a cell cycle specific anticancer medication
Q. Is Alcarb 450 Injection FDA approved?
Yes Alcarb 450 Injection is an FDA approved drug
Q. Is it a platinum based drug?
Yes carboplatin is a platinum based drug and is effectively used in combination with other drug
Q. Does Alcarb 450 Injection cause neuropathy/ hearing loss/ hair loss/ weight gain/ constipation/ leukemia?
Yes Alcarb 450 Injection is known to cause side effects like neuropathy, hearing loss, hair loss, weight gain, and constipation. Please inform your doctor about any side-effect that you may observe on taking this drug. Infertility while on therapy may be caused as a side effect of this drug but it may be reverse after stopping the therapy. Yes Alcarb 450 Injection may cause leukemia if it is used for a long duration.
Q. Is Alcarb 450 Injection a generic?
Yes, Alcarb 450 Injection is a generic platinum-based compound
Q. Is Alcarb 450 Injection vesicant/cardio-toxic/ anthracycline?
No Alcarb 450 Injection is not cardio-toxic/ anthracycline/vesicant
Q. Is Alcarb 450 Injection used for breast cancer?
It is used to treat advanced stage breast cancer
Q. Is Alcarb 450 Injection available in pill form?
No Alcarb 450 Injection is not available in pill form
In Ovarian cancer
Ovarian cancer is a cancer that begins in the female organs that produce eggs (ovaries). This type of cancer is usually detected very late and can be fatal too. It usually spreads to the pelvis and stomach. Alcarb 450 Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is an effective medicine but has some side effects that may be bothersome. So, you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.
In Small cell lung cancer
Small cell lung cancer is a fast-growing type of lung cancer commonly caused by smoking that starts with small tumors in the lungs but eventually spreads to the other parts of the body as well. Alcarb 450 Injection helps treat such types of cancer and may be given alone or in combination with other medicines. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.show moreshow less
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Diarrhea
Peripheral neuropathy (tingling and numbness of feet and hand)
Stomatitis (Inflammation of the mouth)
Decreased white blood cell count (neutrophils)
Increased liver enzymes
Low blood platelets
Fatigue
Anemia (low number of red blood cells)
Vomiting
Nausea
Alcohol:CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Alcarb 450 Injection. Please consult your doctor.
Pregnancy:CONSULT YOUR DOCTOR
Alcarb 450 Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding:UNSAFE
Alcarb 450 Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving:UNSAFE
Alcarb 450 Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney:CAUTION
Alcarb 450 Injection should be used with caution in patients with kidney disease. Dose adjustment of Alcarb 450 Injection may be needed. Please consult your doctor.Use of Alcarb 450 Injection is not recommended in patients with severe kidney disease. Regular monitoring of kidney function tests may be advised while you are taking this medicine.
Liver:SAFE IF PRESCRIBED
Alcarb 450 Injection is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Alcarb 450 Injection may not be needed in these patients. Please consult your doctor.
Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1689.
Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 944.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 205-207.
U.S. National Library of Medicine. Carboplatin. view
Carboplatin. Maidenhead: Hospira UK Limited; 20 Jul. 2005 . view
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