Alkem Manitol 20% Infusion

Alkem Manitol 20% Infusion is a medicine used in the treatment of acute renal (kidney) failure, cerebral edema (accumulation of excessive fluid in the brain) and to reduce the pressure inside the eyes in a condition called glaucoma.

Alkem Manitol 20% Infusion works by removing excess water and also relieves inflammation in the affected areas. It may be used alone or in combination with other medicines. It is administered as an injection under the supervision of a medical professional and should not be self administered. Take this medicine in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember.

Some common side effects of this medicine include nausea, vomiting, headache, and dehydration. You may also notice some injection site reactions such as pain, redness or swelling. However, these are temporary and usually subside on their own after some time. Please consult your doctor if these do not subside or bother you. Regular monitoring by blood tests may be required while using this medicine.

Acute renal failure

Cerebral edema (accumulation of excessive fluid in the brain)

Glaucoma

Your doctor or nurse will give you this medicine. Kindly do not self-administer.

Alkem Manitol 20% Infusion is an inert substance with high osmotic pressure. It draws water into the kidney, which in turn increases the amount of urine production. Alkem Manitol 20% Infusion is also used to lower the pressure inside the eye or swelling around the brain.

Q: What if you forget to take Alkem Manitol Infusion?
A: If you miss a dose of Alkem Manitol 20% Infusion, please consult your doctor.n

It is given as an injection into the veins by a doctor or healthcare professional.

Your doctor may get regular blood tests done to monitor sodium and potassium level, kidney function, and lung function while you are taking this medicine.

Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

It is given as an injection into the veins by a doctor or healthcare professional.

Your doctor may get regular blood tests done to monitor sodium and potassium level, kidney function, and lung function while you are taking this medicine.

Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Nausea

Vomiting

Headache

Dehydration

Injection site reactions (pain, swelling, redness)

Alcohol:CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Alkem Manitol 20% Infusion. Please consult your doctor.

Pregnancy:CONSULT YOUR DOCTOR

Alkem Manitol 20% Infusion may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding:SAFE IF PRESCRIBED

Alkem Manitol 20% Infusion is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Driving:SAFE

Alkem Manitol 20% Infusion does not usually affect your ability to drive.

Kidney:SAFE IF PRESCRIBED

Alkem Manitol 20% Infusion is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Alkem Manitol 20% Infusion may not be needed in these patients. Please consult your doctor.

Liver:CONSULT YOUR DOCTOR

There is limited information available on the use of Alkem Manitol 20% Infusion in patients with liver disease. Please consult your doctor.

Ives HE. Diuretic Agents. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 263.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 836-37.
Mannitol. Thetford, Norfolk: Baxter Healthcare Ltd.; 2003 [revised Jan. 2017]. [Accessed 25 Mar 2019] (online) Available from: View