Amis 400 Tablet is a prescription medicine used in the treatment of schizophrenia, a mental disorder that can result in hallucinations or delusions and also adversely affects a person’s ability to think and behave.
Amis 400 Tablet may be taken with or without food, preferably before bedtime. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember. Do not skip any doses and finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to your doctor as it may worsen your symptoms.
Some common side effects of this medicine include nausea, vomiting, and dryness in the mouth. Initially, this medicine may cause a sudden drop in blood pressure when you change positions, so it is better to rise slowly if you have been sitting or lying down. It also causes dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. This medicine can lead to weight gain and may increase your blood sugar and cholesterol levels. However, modifying your lifestyle by having a healthy diet and exercising regularly can reduce this side effect.
Schizophrenia
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Amis 400 Tablet may be taken with or without food, but it is better to take it at a fixed time.
Amis 400 Tablet is an atypical antipsychotic. It works by modulating the action of certain chemical messengers in the brain that affect thoughts.
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Amis 400 Tablet helps treat schizophrenia.
Take it at bedtime to avoid feeling sleepy during the day.
Use caution while driving or doing anything that requires concentration as Amis 400 Tablet can cause dizziness and sleepiness.
To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
Do not consume alcohol while on treatment with this medicine as it may worsen the side effects.
It may cause increased weight, blood sugar, cholesterol, and triglycerides (fat) levels. Eat healthy and exercise regularly.
Inform your doctor if you are pregnant, planning to conceive or breastfeeding.
Do not stop taking Amis 400 Tablet without talking to your doctor first as it may cause worsening of symptoms.
Q. Does Amis 400 Tablet make you sleepy?
Yes, Amis 400 Tablet may make you sleepy, drowsy, less alert, and may even blur your vision. If you experience these symptoms you should not drive or operate heavy machinery.
Q. When should I take Amis 400 Tablet?
The time of taking the medicine will be suggested by your doctor depending upon your dose. Doses up to 300 mg can be taken anytime of the day but preferably at the same time each day. Doses more than 300 mg can be taken half in the morning and half in the evening. You can take the medicine during or between meals.
Q. What does Amis 400 Tablet do to the brain?
Amis 400 Tablet belongs to antipsychotic class of medicines. It acts against dopamine receptors in the brain. Dopamine is a neurotransmitter which helps in regulating mood and behavior. Schizophrenia is associated with an overactivity of dopamine in the brain, and this overactivity may cause delusions and hallucinations. Amis 400 Tablet prevents this excessive activity of dopamine in the brain which helps in treating symptoms of schizophrenia.
Q. Does Amis 400 Tablet help with anxiety?
No, there is no data to support the use of Amis 400 Tablet in the treatment of anxiety. On the contrary, anxiety is a common side effect of Amis 400 Tablet.
Q. Can I stop taking Amis 400 Tablet after some time?
No, you should keep taking Amis 400 Tablet as long as your doctor has advised. Do not stop the medication even if you feel better. Stopping it suddenly may worsen your condition or symptoms may come back. Talk to your doctor who will gradually reduce your dose.
Q. Who should not take Amis 400 Tablet?
You should not take Amis 400 Tablet if you are under 15 years of age, allergic to it, have breast cancer or a tumor known as prolactinoma. Avoid taking Amis 400 Tablet if you are breastfeeding, have tumor of adrenal glands (pheochromocytoma), or if you are taking certain medicines like levodopa, medicines to treat heart rhythm disorders, etc.
Q. Is Amis 400 Tablet addictive?
No, there is no evidence to say that Amis 400 Tablet causes addiction. Also, its use is not known to have any tendency for abuse.
Q. What are the withdrawal symptoms of Amis 400 Tablet?
Suddenly stopping Amis 400 Tablet may cause withdrawal symptoms which include nausea, vomiting, sweating, difficulty sleeping, extreme restlessness, muscle stiffness or abnormal movements, or your original condition may come back. Therefore, it is advised to gradually reduce the dose of Amis 400 Tablet.
In Schizophrenia
Schizophrenia is a mental disorder in which a person’s thinking ability, feelings and behavior become abnormal. Amis 400 Tablet helps restore the chemical imbalances in the brain that are responsible for such changes. It improves thoughts, behavior and enhances the quality of life. Take it as prescribed by the doctor and follow your doctor’s instructions carefully.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Increased prolactin level in blood
Parkinsonism
Akathisia (inability to stay still)
Dystonia (involuntary muscle contractions)
Decreased blood pressure
Weight gain
Constipation
Dryness in mouth
Vomiting
Nausea
Alcohol:UNSAFE
It is unsafe to consume alcohol with Amis 400 Tablet.
Pregnancy:CONSULT YOUR DOCTOR
Amis 400 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding:CONSULT YOUR DOCTOR
Amis 400 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving:UNSAFE
Amis 400 Tablet may cause side effects which could affect your ability to drive.You may feel less alert, drowsy or sleepy while taking this medicine. This may affect your driving ability.
Kidney:CAUTION
Amis 400 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Amis 400 Tablet may be needed. Please consult your doctor.Use of Amis 400 Tablet is not recommended in patients with severe kidney disease.
Liver:SAFE IF PRESCRIBED
Amis 400 Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Amis 400 Tablet may not be needed in these patients. Please consult your doctor.
Stahl SM, editor. Amisulpride. In: Stahl’s Essential Pschopharmacology: Prescriber’s Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 17-22.
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