Amitryptyline 10mg Tablet

Amitryptyline 10mg Tablet is normally taken before bedtime because it can make you feel sleepy. It can be taken with or without food. The dose and how often you need to take it will be decided by your doctor so that you get the right amount to control your symptoms. The initial dose should be increased with great caution under close supervision. This medicine may not work straight away and it could be several weeks before you get the full effects.
How long you need to use it will depend on what you are taking it for, but it is important to continue taking this medication even if you feel well. Do not stop taking the medicine suddenly without talking to your doctor. Stopping the medicine suddenly can worsen your conditions or cause other symptoms. Your dose may be modified or gradually decreased before stopping the medication.

The most common side effects of this medicine include nausea, constipation, sweating, dry mouth, sleepiness, tremor, dizziness, headache, speech disorder, accommodation disorder, palpitations, increased heart rate, orthostatic hypotension, and nasal congestion. It may also make you aggressive or confused and can lead to weight gain in some people. This medicine is not addictive, but you can experience additional side effects (withdrawal symptoms) if you stop taking it suddenly. Most of the common side effects tend to be mild. Your doctor may be able to suggest ways of preventing or reducing side effects if they bother you or do not go away. Serious side effects associated with this medicine are rare.

Treatment of Depression
Neuropathic pain
Treatment of Migraine

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Amitryptyline 10mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

Amitryptyline 10mg Tablet contains Amitriptyline, a tricyclic antidepressant. It has anticholinergic and sedative properties. It prevents the reuptake, and hence the inactivation of neurotransmitters called noradrenaline and serotonin, that are present at the nerve terminals in our brain. Reuptake prevention of these monoamine neurotransmitters potentiate their action in the brain. This appears to be associated with the antidepressant activity and helps in regulating the mood. It also stops the transmission of pain signals from nerves to the brain thereby relieving neuropathic pain (pain from damaged nerves).

If you miss a dose of Amitryptyline 10mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

It may take 4 to 6 weeks for Amitryptyline 10mg Tablet to start working. Keep taking it as prescribed.

It may cause sleepiness. Take it at bedtime and do not drive or do anything requiring concentration until you know how it affects you.

Avoid consuming alcohol when taking Amitryptyline 10mg Tablet as it may cause excessive sleepiness.

Monitor your weight during the treatment as this medicine can cause weight gain and increased appetite.

It may cause sudden drop in your blood pressure. Rise slowly if you have been sitting or lying down.

Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.

Pay close attention to any changes, especially sudden changes, in mood, behaviors, thoughts, or feelings. This is very important when an antidepressant medicine is started or when the dose is changed.

Pay close attention to any changes, especially sudden changes, in mood, behaviors, thoughts, or feelings. This is very important when an antidepressant medicine is started or when the dose is changed.

Q. What other lifestyle changes should I make to get maximum benefit of Amitryptyline 10mg Tablet?

Antidepressants, including Amitryptyline 10mg Tablet, are just one of several approaches to treat depression. Certain lifestyle changes can help you get maximum benefit of Amitryptyline 10mg Tablet and help you recover fast. Keeping active and eating a healthy diet can make a significant difference to how quickly you recover from depression. Think positively and try to discuss your thoughts with others to reduce stress. Practice yoga or take up a hobby. Ensure that you have a sound sleep to calm your mind. Stay away from smoking or alcohol consumption as these will only worsen your depression. Take your medicines as prescribed even if you start feeling better.

Q. Is there anything I need to be careful about while on therapy with Amitryptyline 10mg Tablet?

Amitryptyline 10mg Tablet may cause drowsiness and dizziness, especially in the beginning of the treatment. So, avoid driving or using machinery until you know how the medicine affects you. Also, it is not advisable to drink alcohol during treatment with this medicine as it might increase sleepiness.

Q. Can the use of Amitryptyline 10mg Tablet affect my sex life?

Yes, Amitryptyline 10mg Tablet can affect sex life in both men and women. It may cause decreased sexual desire or you may experience discomfort during intercourse. Men may experience inability to develop or maintain an erection during sexual activity and may be unable to have an orgasm. If you notice these symptoms, do not stop taking the medicine but consult your doctor.

Q. I have been taking Amitryptyline 10mg Tablet for depression since a week and recently I have been wanting to harm myself. What should I do? Is it because of the medicine?

You should immediately consult your doctor or go to the hospital. Your suicidal tendencies may have increased because of your disease or the medicine. Generally, Amitryptyline 10mg Tablet takes about 2 weeks to show its effect but may take longer. Therefore, when you start taking Amitryptyline 10mg Tablet, you may have thoughts about killing or harming yourself. This is more common in people who previously had suicidal tendencies or are young adults (less than 25 years old). However, the effect of medicine is different for every individual.

Q. Can Amitryptyline 10mg Tablet cause urinary problems?

Yes, Amitryptyline 10mg Tablet can cause urinary problems. It is more commonly seen in elderly patients who are more than 65 years old. The patient may face difficulty in passing urine which can further lead to a urinary tract infection. Consult your doctor immediately if you develop these symptoms.

Q. If my pain is not relieved, can I take more than the recommended dose?

No, you should use Amitryptyline 10mg Tablet strictly as prescribed by the doctor. If the dose exceeds, you may develop drowsiness, confusion, difficulty in speech, dry mouth, tiredness, difficulty in walking, fever, difficulty in breathing, blue discoloration of the skin and decreased heartbeat. Your pain may not be relieved because Amitryptyline 10mg Tablet takes about 2 weeks to show its effect, but it may take longer in some cases. The duration of treatment can differ from individual to individual. Consult your doctor if your symptoms are not relieved.

Q. Does Amitryptyline 10mg Tablet cause any effect on pregnancy or the newborn?

Do not take Amitryptyline 10mg Tablet during pregnancy unless recommended by the doctor. If you take this medicine during the last trimester of the pregnancy, the newborn may develop symptoms such as irritability, rigidity, irregular body movements, irregular breathing, poor drinking, loud crying, difficulty in urinating and constipation.

Q. I have been prescribed Amitryptyline 10mg Tablet for pain. When will I start feeling better?

You may start feeling better after 2 weeks of starting Amitryptyline 10mg Tablet. However, it may take 4-6 weeks to see the full benefits of the medicine.

Q. Can I stop taking Amitryptyline 10mg Tablet when my pain is relieved?

No, do not stop taking Amitryptyline 10mg Tablet even if the pain is relieved. You should use Amitryptyline 10mg Tablet as advised by the doctor. Stopping the medicine suddenly may cause unpleasant symptoms like headache, feeling unwell, sleeplessness and irritability. Consult your doctor for the duration of the treatment since the dose of Amitryptyline 10mg Tablet needs to be reduced gradually.

Q. How long does Amitryptyline 10mg Tablet take to work?

You may see an improvement in your symptoms after a couple of weeks, although it usually takes between 4 and 6 weeks before you feel the benefits. Do not stop taking Amitryptyline 10mg Tablet after 1 or 2 weeks just because you feel it is not helping your symptoms. Give the medicine at least 6 weeks to work.

Q. How will Amitryptyline 10mg Tablet make me feel?

Antidepressants like Amitryptyline 10mg Tablet help to gradually lift your mood. You may notice that you sleep better and are less anxious. You may worry less about little things that used to bother you. Amitryptyline 10mg Tablet will not make you feel excessively or unusually happy. It will help you feel like yourself again.

In Treatment of Depression

Amitryptyline 10mg Tablet works by affecting the balance of certain chemicals (such as serotonin) in the brain. It helps improve mood and feelings of well-being, relieve anxiety and tension, helps you sleep better, and increase your energy level. Amitryptyline 10mg Tablet is readily absorbed and starts action within approximately 6 hours of taking it orally (by mouth). It is an effective antidepressant but may cause drowsiness. You need to take it regularly as it is prescribed for it to be most effective and should not stop taking it suddenly.

In Neuropathic pain

Amitryptyline 10mg Tablet helps in relieving neuropathic pain caused by nerve damage in certain conditions. These may include painful diabetic neuropathy, post-herpetic neuralgia, or spinal cord disease. It works by affecting chemicals in the brain called neurotransmitters. By relieving pain, it helps improve your quality of life.

In Treatment of Migraine

Amitryptyline 10mg Tablet helps prevent migraines by changing the way that your nerves receive pain signals. By preventing and reducing the frequency of headaches, it can help you carry out your daily activities and have a better quality of life.show moreshow less

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Difficulty in paying attention

Palpitations

Accomodation disorder

Speech disorder

Tremor

Nausea

Headache

Dizziness

Sweating

Sleepiness

Nasal congestion (stuffy nose)

Aggressive behavior

Weight gain

Increased heart rate

Orthostatic hypotension (sudden lowering of blood pressure on standing)

Dryness in mouth

Constipation

Alcohol:UNSAFE

It is unsafe to consume alcohol with Amitryptyline 10mg Tablet.

Pregnancy:CONSULT YOUR DOCTOR

Amitryptyline 10mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding:CONSULT YOUR DOCTOR

Amitryptyline 10mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving:UNSAFE

Amitryptyline 10mg Tablet may cause side effects which could affect your ability to drive.Amitryptyline 10mg Tablet may impair your alertness which may affect your ability to drive.

Kidney:SAFE IF PRESCRIBED

Amitryptyline 10mg Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Amitryptyline 10mg Tablet may not be needed in these patients. Please consult your doctor.

Liver:CAUTION

Amitryptyline 10mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Amitryptyline 10mg Tablet may be needed. Please consult your doctor.Use of Amitryptyline 10mg Tablet is not recommended in patients with severe liver disease.

Stahl SM, editor. Amitriptyline. In: Stahl’s Essential Pschopharmacology: Prescriber’s Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 25-30.

Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 58-59.

Amitriptyline. Princeton: Sandoz Inc; 2014. view

Drugs and Lactation Database. Bethesda : National Library of Medicine ; 2006. Amitriptyline. . view

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