Amize 12.5 mg/5 mg Tablet is a combination of two medicines. It is used in the treatment of depression associated with anxiety. It helps in regulating mood and to reduce anxiety.
Amize 12.5 mg/5 mg Tablet is taken with or without food. However, it is advised to take it at a fixed time each day to maintain a consistent level of medicine in the blood. In case you miss a dose of this medicine, take it as soon as you remember. Never skip any dose and finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to the doctor as it may worsen your symptoms. Taking this medicine for a long time may require regular monitoring of blood and liver functions.
Some common side effects of this medicine include constipation, difficulty in urination, weight gain, confusion, orthostatic hypotension (sudden lowering of blood pressure on standing). This medicine may cause weight loss. In case of losing weight, consult a dietitian for dietary supplements or try to increase your food portion. Most of the common side effects tend to be mild. Your doctor may be able to suggest ways of preventing or reducing side effects if they bother you or do not go away. Serious side effects are rare. Remember to inform your doctor if you develop any unusual changes in mood as it may lead to suicidal thoughts.
Take caution while taking medicine if you are suffering from liver disease. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
Treatment of Depression
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Amize 12.5 mg/5 mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Amize 12.5 mg/5 mg Tablet is a combination of two medicines: Amitriptyline and Chlordiazepoxide, which treats depression. Amitriptyline is a tricyclic antidepressant which increases the levels of chemical messengers in the brain that help in regulating the mood and treat depression. Chlordiazepoxide is a benzodiazepine (BZD) which works by increasing the action of GABA, a chemical messenger which suppresses the abnormal and excessive activity of the nerve cells in the brain.
If you miss a dose of Amize 12.5 mg/5 mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Amize 12.5 mg/5 mg Tablet is prescribed for the treatment of depression.
It can take a week or two after starting this treatment before the effect begins to build up, and 4-6 weeks before you feel the full benefit. Do not stop taking it after a week or two, feeling it is not helping.
Do not stop taking Amize 12.5 mg/5 mg Tablet unless your doctor tells you to do so. Stopping treatment suddenly can cause problems and your doctor will probably want you to reduce your dose gradually when this becomes necessary.
Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress.
Inform your doctor if you are taking any other antidepressants.
Inform your doctor immediately if you get thoughts about harming yourself or ending your life.
Avoid alcohol while taking Amize 12.5 mg/5 mg Tablet.
If you have diabetes, you will be asked to monitor your blood glucose level regularly as Amize 12.5 mg/5 mg Tablet may affect the levels of sugar in your blood.
Amize 12.5 mg/5 mg Tablet is prescribed for the treatment of depression.
It can take a week or two after starting this treatment before the effect begins to build up, and 4-6 weeks before you feel the full benefit. Do not stop taking it after a week or two, feeling it is not helping.
Do not stop taking Amize 12.5 mg/5 mg Tablet unless your doctor tells you to do so. Stopping treatment suddenly can cause problems and your doctor will probably want you to reduce your dose gradually when this becomes necessary.
Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress.
Inform your doctor if you are taking any other antidepressants.
Inform your doctor immediately if you get thoughts about harming yourself or ending your life.
Avoid alcohol while taking Amize 12.5 mg/5 mg Tablet.
If you have diabetes, you will be asked to monitor your blood glucose level regularly as Amize 12.5 mg/5 mg Tablet may affect the levels of sugar in your blood.
Q. Are there any important warnings associated with use of Amize 12.5 mg/5 mg Tablet?
During the first few months of treatment, Amize 12.5 mg/5 mg Tablet may increase suicidal thoughts or actions in some patients. Patients having mood or behavioral disorder have a high risk of developing suicidal thoughts and actions. You should pay close attention and report your doctor of any such behavior or mood changes. Make sure that you visit the doctor for the scheduled follow-up appointments.
Q. Can I stop taking Amize 12.5 mg/5 mg Tablet when my symptoms are relieved?
No, you should continue to take Amize 12.5 mg/5 mg Tablet, even if you feel well. If you stop Amize 12.5 mg/5 mg Tablet suddenly, serious withdrawal symptoms may occur. Consult your doctor if the symptoms are relieved, he might decrease your dose gradually.
Q. How to manage weight gain associated with the use of Amize 12.5 mg/5 mg Tablet?
There are reports which suggest that the use of Amize 12.5 mg/5 mg Tablet can cause weight gain. If you maintain good eating habits and exercise regularly, you might not gain any weight. An important to remember is that it is easier to prevent weight gain than losing increased weight.
Q. What are the instructions for storage and disposal of Amize 12.5 mg/5 mg Tablet?
Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
Q. Can the use of Amize 12.5 mg/5 mg Tablet cause sleepiness?
Yes, Amize 12.5 mg/5 mg Tablet can make you feel sleepy. Avoid driving, operating machinery, working at heights or participating in potentially dangerous activities till you know how this medicine affects you.
Q. Can the use of Amize 12.5 mg/5 mg Tablet affect my sexual life?
The use of Amize 12.5 mg/5 mg Tablet can affect the sexual life of both men and women. Most commonly caused problems are decreased sexual desire, erectile dysfunction (inability to develop or maintain erection during the sexual activity) and inability to reach orgasm. It can also cause a decrease in satisfaction and cause discomfort while having sex. If you experience these problems, discuss with your doctor.
Q. Can I drink alcohol while taking Amize 12.5 mg/5 mg Tablet?
No, do not drink alcohol while you are taking Amize 12.5 mg/5 mg Tablet. Drinking alcohol can increase the severity of drowsiness or sleepiness caused by Amize 12.5 mg/5 mg Tablet.
Q. Can the use of Amize 12.5 mg/5 mg Tablet change the color of urine?
Yes, Amize 12.5 mg/5 mg Tablet can the change the color of the urine to blue or green. This change of color is expected while using Amize 12.5 mg/5 mg Tablet, and it is not harmful. Your urine color becomes normal once you stop taking Amize 12.5 mg/5 mg Tablet.
Q. How long does Amize 12.5 mg/5 mg Tablet take to work?
Everybody responds differently to the treatment. In general, it can take several weeks to feel the full benefits of Amize 12.5 mg/5 mg Tablet, although some people will start to feel better sooner. When taking Amize 12.5 mg/5 mg Tablet, it is important to give it time to work.
In Treatment of Depression
Amize 12.5 mg/5 mg Tablet works by affecting the balance of certain chemicals (such as serotonin) in the brain. It helps improve mood and feelings of wellbeing, relieve anxiety and tension, helps you sleep better, and increase your energy level. It is an effective antidepressant but may cause drowsiness. You need to take it regularly as it is prescribed for it to be most effective and should not stop taking it suddenly.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Memory impairment
Depression
Uncoordinated body movements
Increased heart rate
Dryness in mouth
Blurred vision
Tiredness
Orthostatic hypotension (sudden lowering of blood pressure on standing)
Confusion
Weight gain
Difficulty in urination
Constipation
Alcohol:UNSAFE
It is unsafe to consume alcohol with Amize 12.5 mg/5 mg Tablet.
Pregnancy:CONSULT YOUR DOCTOR
Amize 12.5 mg/5 mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding:CONSULT YOUR DOCTOR
Amize 12.5 mg/5 mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving:UNSAFE
Amize 12.5 mg/5 mg Tablet may cause side effects which could affect your ability to drive.As Amize 12.5 mg/5 mg Tablet may make you feel drowsy or affect your concentration and this may affect your ability to drive.
Kidney:SAFE IF PRESCRIBED
Amize 12.5 mg/5 mg Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Amize 12.5 mg/5 mg Tablet may not be needed in these patients. Please consult your doctor.
Liver:CAUTION
Amize 12.5 mg/5 mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Amize 12.5 mg/5 mg Tablet may be needed. Please consult your doctor.
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