Aplaz 0.5mg Tablet
Aplaz 0.5mg Tablet may be taken with or without food. However, take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor as it has a high potential of habit-forming. If you have missed a dose, take it as soon as you remember it and finish the full course of treatment even if you feel better. You should not stop this medicine suddenly without talking to your doctor as it may increase the seizure frequency and can cause nausea, anxiety, flu-like symptoms, and muscle pain.
Aplaz 0.5mg Tablet
Basic Information
Important information about this medicine
About This Medicine
General information about this product
Aplaz 0.5mg Tablet is a prescription medicine used to treat epilepsy (seizures) and anxiety disorder. It helps to decrease the abnormal and excessive activity of the nerve cells and calms the brain.
Aplaz 0.5mg Tablet may be taken with or without food. However, take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor as it has a high potential of habit-forming. If you have missed a dose, take it as soon as you remember it and finish the full course of treatment even if you feel better. You should not stop this medicine suddenly without talking to your doctor as it may increase the seizure frequency and can cause nausea, anxiety, flu-like symptoms, and muscle pain.
Some common side effects of this medicine include fatigue, depression and impaired coordination. It may also cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. It is important to inform your doctor if you develop any unusual changes in mood or depression as this medicine may cause suicidal thoughts.
03Uses
Treatment of Anxiety disorder
Treatment of Epilepsy/Seizures
04How To Use
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Aplaz 0.5mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
05How It Works
Aplaz 0.5mg Tablet is a benzodiazepine. It works by increasing the action of a chemical messenger (GABA) which suppresses the abnormal and excessive activity of the nerve cells in the brain.
06What If You Miss A Dose?
If you miss a dose of Aplaz 0.5mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
07Benefits
In Treatment of Anxiety disorder
Aplaz 0.5mg Tablet stops your brain from releasing the chemicals that make you feel anxious so it can reduce the symptoms of excessive anxiety and worry. It can also reduce feelings of restlessness, tiredness, difficulty concentrating, feeling irritable and sleep problems that often come with Anxiety Disorder. It will therefore help you go about your daily activities more easily and be more productive. Keep taking this medicine even if you feel well. Stopping suddenly can cause serious problems.
In Treatment of Epilepsy/Seizures
Aplaz 0.5mg Tablet slows down electrical signals in the brain which cause seizures (fits). It can also help reduce symptoms such as confusion, uncontrollable jerking movements, loss of awareness, and fear or anxiety. The medicine can allow you to do some activities that you would otherwise be forbidden or scared to do (such as swimming and driving). It can take a few weeks for this medicine to work (because the dose has to be increased slowly) and during this time you may still have seizures. Do not stop using this medicine even if you feel well, until your doctor advises you to. Missing doses may trigger a seizure.show moreshow less
08Side Effects
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Memory impairment
Impaired coordination
Fatigue
Drowsiness
Dizziness
Depression
09Safety Information
Alcohol:UNSAFE
It is unsafe to consume alcohol with Aplaz 0.5mg Tablet.
Pregnancy:CONSULT YOUR DOCTOR
Aplaz 0.5mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding:SAFE IF PRESCRIBED
Aplaz 0.5mg Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Driving:UNSAFE
Aplaz 0.5mg Tablet may cause side effects which could affect your ability to drive.
Kidney:CAUTION
Aplaz 0.5mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Aplaz 0.5mg Tablet may be needed. Please consult your doctor.Use of Aplaz 0.5mg Tablet can cause excessive sleepiness in patients with end stage kidney disease.
Liver:CAUTION
Aplaz 0.5mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Aplaz 0.5mg Tablet may be needed. Please consult your doctor.
10Drug Tips
The addiction / habit-forming potential of this medicine is very high. Take it only as per the dose and duration advised by your doctor
It may cause dizziness. Do not drive or do anything that requires mental focus until you know how this medicine affects you.
Avoid consuming alcohol as it may increase dizziness and drowsiness.
Inform your doctor if you are pregnant, planning to conceive or breastfeeding.
Inform your doctor if you experience worsen anxiety, depression angry, or violent behavior and mania while taking this medicine.
Do not stop taking medication suddenly without talking to your doctor as that may lead to nausea, anxiety, agitation, flu-like symptoms, sweating, tremor, and confusion.
References
Sources and references
Stahl SM, editor. Clonazepam. In: Stahl’s Essential Pschopharmacology: Prescriber’s Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 137-41.
McNamara JO. Pharmacotherapy of the Epilepsies. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 598-99.
Porters RJ, Meldrum BS. Antiseizure Drugs. Sedative-Hypnotic Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 415.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 301-303.
Clonazepam. Roche; . view
Drugs and Lactation Database. Bethesda : National Library of Medicine ; 2006. Clonazepam. . view
Clonazepam. Boucherville, Québec: Sandoz Canada Inc.; 2018. view
Central Drugs Standard Control Organisation . view
