Apllinol 300mg Tablet
Apllinol 300mg Tablet should be taken after food. You should keep taking it as recommended by your doctor even when you are not having a gout attack. If you stop, your symptoms may get worse because more crystals form in your joints and kidneys. You can help yourself by making some changes to your diet and drinking plenty of fluids.
Apllinol 300mg Tablet
Basic Information
Important information about this medicine
About This Medicine
General information about this product
Apllinol 300mg Tablet is a medicine used to treat and prevent gout. Gout happens when there is too much uric acid in your body and it forms into crystals that can appear around your joints and kidneys and cause pain. This medicine helps to keep uric acid levels low.
Apllinol 300mg Tablet should be taken after food. You should keep taking it as recommended by your doctor even when you are not having a gout attack. If you stop, your symptoms may get worse because more crystals form in your joints and kidneys. You can help yourself by making some changes to your diet and drinking plenty of fluids.
Some of the common side effects of this medicine are rash, nausea, and diarrhea. Your doctor may help with ways to reduce or prevent these symptoms. Some people may get a severe allergic reaction that needs urgent medical attention. Talk to your doctor straight away if you get symptoms of liver disease including nausea that does not stop, yellowing skin or eyes, or dark urine.
To make sure it is safe for you, before taking this medicine, let your doctor know if you have or have had heart failure, heart problems, stroke, kidney or liver disease, or thyroid problems. Do not use this medicine if you are pregnant or breastfeeding. Check with your doctor. You will be asked for regular blood tests to check that your liver is working properly.
03Uses
Treatment of Gout
04How To Use
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Apllinol 300mg Tablet is to be taken with food.
05How It Works
Apllinol 300mg Tablet is a xanthine oxidase inhibitor. It works by decreasing blood uric acid, which is the chemical that causes gout.
06What If You Miss A Dose?
If you miss a dose of Apllinol 300mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
07Benefits
In Treatment of Gout
Apllinol 300mg Tablet is used to prevent and treat gout. Gout is caused by too much uric acid in your body. When the level becomes too high, crystals may form in and around certain joints and your kidneys. This can cause sudden and severe pain, redness, warmth, and swelling. This medicine works by preventing crystals from forming and reducing the levels of uric acid in your blood. This makes it less likely that you will suffer the symptoms and make them milder if you do have them. It is usually for long-term treatment and should be taken regularly until the dose is completed.
08Side Effects
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Nausea
Diarrhea
Skin rash
09Safety Information
Alcohol:CAUTION
Caution is advised when consuming alcohol with Apllinol 300mg Tablet. Please consult your doctor.
Pregnancy:CONSULT YOUR DOCTOR
Apllinol 300mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding:SAFE IF PRESCRIBED
Apllinol 300mg Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Driving:UNSAFE
Apllinol 300mg Tablet may cause side effects which could affect your ability to drive.Occasionally drowsiness, dizziness or vertigo, ataxia and visual disturbances, may occur when taking Apllinol 300mg Tablet. This may affect your driving ability.
Kidney:CAUTION
Apllinol 300mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Apllinol 300mg Tablet may be needed. Please consult your doctor.
Liver:CAUTION
Apllinol 300mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Apllinol 300mg Tablet may be needed. Please consult your doctor.
10Drug Tips
Your doctor has prescribed Apllinol 300mg Tablet to reduce episodes of gout attack.
Take Apllinol 300mg Tablet with food to avoid stomach upset.
Take plenty of fluids (2-3 litres) daily while on Apllinol 300mg Tablet.
Notify your doctor if you develop a rash. This could be a sign of allergy and should go away on discontinuing Apllinol 300mg Tablet.
When you first start taking this medicine, you might have more gout attacks. Do not stop Apllinol 300mg Tablet on having an acute attack of gout as that could make an attack worse.
Your doctor may check your liver function before starting treatment and regularly thereafter. Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain.
Do not consume alcohol while taking this medicine as it may cause your gout to flare up.
References
Sources and references
Furst DE, Ulrich RW, Varkey-Altamirano C. Nonsteroidal Anti-Inflammatory Drugs, Disease Modifying Antirheumatic Drugs, Nonopioids Analgesics, & Drugs Used in Gout. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 638-39.
Grosser T, Smyth E, FitzGerald GA. Anti-Inflammatory, Antipyretic, and Analgesic Agents; Pharmacotherapy of Gout. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 996-97.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 40-42.
Drugs.com. Allopurinol Pregnancy and Breastfeeding Warnings. view
Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr . 2004;80:S189-S198. view
