Composition Aprepitant (150mg)
Rx Prescription Required
Pack vial of 1 Injection
Storage Store in a refrigerator (2 – 8ยฐC). Do not freeze.
Chemical Class Phenylmorpholine Derivative
Action Class NK1 Antagonists
Habbit Forming
Manufacturer Glenmark Pharmaceuticals Ltd
Manufacturer address Glenmark Pharmaceuticals Limited, B/2, Mahalaxmi Chambers, 22, Bhulabhai Desai Road, Mumbai โ 400 026.

Aprecap 150mg Injection
Aprecap 150mg Injection is a prescription medicine used to prevent nausea and vomiting caused by chemotherapy. It is also used in the prevention of postoperative nausea and vomiting in adults.
Basic Info
Description
Aprecap 150mg Injection is given by your doctor or nurse. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early, your symptoms may come back, and your condition may worsen. Let your doctor know about all other medications you are taking as some may affect, or be affected by this medicine.
The most common side effects are headache, hiccups, loss of appetite, fatigue, and constipation. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects. This medicine may also cause diarrhea, so it is beneficial to drink plenty of fluids while taking this medicine as it may help to prevent dehydration. It may also cause dizziness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can worsen your sleepiness.
Before taking this medicine, you should tell your doctor if you are pregnant, planning a pregnancy, or breastfeeding. You should tell your doctor if you have any kidney or liver diseases so that your doctor can prescribe a suitable dose for you.
Uses
Nausea and vomiting due to chemotherapy
How To Use
Your doctor or nurse will give you this medicine. Kindly do not self administer.
MOA
Aprecap 150mg Injection is an antiemetic medication. It works by blocking the action of a chemical messenger (neurokinin) in the brain that may cause nausea and vomiting during anti-cancer treatment (chemotherapy).
What If
If you miss a dose of Aprecap 150mg Injection, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Drug Tips
Aprecap 150mg Injectionย helps prevent nausea and vomiting caused by certain chemotherapy medicines.
Itย will not help if you already have nausea and vomiting.
Do not use it continuously for a long time.
It is recommended to take Aprecap 150mg Injection 1 hour before chemotherapy treatment (Day 1) and in the morning on Days 2 and 3.
Aprecap 150mg Injection may be unsafe to use if you are pregnant, planning a pregnancy, or breastfeeding.ย
Faqs
Q. Does Aprecap 150mg Injection help treat nausea and vomiting?
No, this medicine will not treat nausea or vomiting that has already started. Aprecap 150mg Injection is used with other medications to help prevent nausea and vomiting caused by cancer drug treatment (chemotherapy). It prevents the feeling of sickness by blocking the body’s natural substances that cause nausea and vomiting.
Q. What are some of the serious side-effects of Aprecap 150mg Injection?
Some of the serious side-effects of this medicine are rash, itching, skin peeling or blisters, difficulty breathing or swallowing.
Q. Does Aprecap 150mg Injection reduce the effectiveness of contraceptives?
This medicine can make hormonal birth control less effective, including birth control pills, injections, implants, skin patches, and vaginal rings. To prevent pregnancy while using Aprecap 150mg Injection, use a barrier form of birth control like condom, diaphragm, or cervical cap. Keep using the barrier form of birth control for 1 month after your last dose of aprepitant.
Q. Is Aprecap 150mg Injection given before or after chemotherapy?
Aprecap 150mg Injection is administered 1 hour before your chemotherapy on days 1, 2, and 3 of your treatment.
Q. Should I avoid any food and drinks while taking Aprecap 150mg Injection?
You can continue with your normal diet unless your doctor tells you otherwise. However, it is advisable to sip water regularly to prevent you from becoming dehydrated, eating small, simple but nourishing snacks every few hours rather than large meals, and sucking on hard candy or popsicles during chemotherapy to prevent nausea and vomiting.
Q. What should I avoid during chemotherapy?
During chemotherapy, it is advisable to avoid caffeine as it can make you feel dehydrated, avoid fatty fried, spicy, and overly sweet foods, as they may induce nausea, avoid alcohol and smoking. It is also advisable to avoid crowds or people with colds, as you may be at risk of infection as well as sun exposure to prevent rashes and dry skin.
Benifits
In Nausea and vomiting due to chemotherapy
Aprecap 150mg Injection blocks the action of chemicals in the body that can make you feel or be sick. It is often used to prevent nausea and vomiting that may be caused due to some medicines or cancer treatment. This medicine helps you recover more comfortably from cancer treatments such as radiation therapy or chemotherapy. It is also effective at preventing nausea and vomiting after an operation (in adults only). It is given as an injection by a doctor and should not be self-administered.
Side Effects
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if youโre worried about them
Diarrhea
Constipation
Fatigue
Loss of appetite
Hiccup
Dizziness
Headache
Safety Profile
Alcohol:CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Aprecap 150mg Injection. Please consult your doctor.
Pregnancy:CONSULT YOUR DOCTOR
Aprecap 150mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding:CONSULT YOUR DOCTOR
Aprecap 150mg Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving:UNSAFE
Aprecap 150mg Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney:SAFE IF PRESCRIBED
Aprecap 150mg Injection is safe to use in patients with kidney disease. No dose adjustment of Aprecap 150mg Injection is recommended.
Liver:SAFE IF PRESCRIBED
Aprecap 150mg Injection is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Aprecap 150mg Injection may not be needed in these patients. Please consult your doctor.
Refferences
McQuaid KR. Drugs Used in the Treatment of Gastrointestinal Diseases. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 1086.
MedlinePlus. Aprepitant. view
DailyMed. Aprepitant. view
Central Drugs Standard Control Organisation . view

