Arzi 1000mg Injection

Composition Dacarbazine (1000mg)
Rx Prescription Required
Pack vial of 1 Powder for Injection
Storage Store below 30°C
Chemical Class Triazene Derivative
Action Class Alkylating agent
Habbit Forming No
Manufacturer Miracalus Pharma Pvt Ltd
Manufacturer address 213, Shivai Dongre Industrial Premises, Andheri – Kurla Road, Andheri(E), Mumbai – 400 072, Maharashtra, India.

Arzi 1000mg Injection is given as an injection into a vein by the healthcare professional, but better if injected at the same time every day. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include nausea, vomiting, and decreased white blood cell count, and injection site pain,. If they do not go away or get worse, tell your doctor. There may be ways of preventing or reducing these effects. It is very strong medicine and some people may develop serious side effects while taking it. This medicine may lower your ability to fight infections and lead to problems with your blood, liver or kidneys. Inform your doctor if you notice unusual bleeding or bruising, lack of energy, loss of appetite, and yellowing of eyes. Your doctor will advise you regular blood tests to check for these.

Before taking it, tell your doctor if you have liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Malignant melanoma
Hodgkin’s disease

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Arzi 1000mg Injection is an anti-cancer medication. It works by damaging the genetic material (DNA and RNA) of the cancer cells. This stops their growth and multiplication.

If you miss a dose of Arzi 1000mg Injection, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Arzi 1000mg Injection is given as an injection into veins under the supervision of a doctor. 

Q. How is Arzi 1000mg Injection administered?

Arzi 1000mg Injection is administered as infusion or injection. Absorption by mouth is slow and varies, therefore, intravenous (given through vein) infusion or injection administration is preferred.

Q. Is Arzi 1000mg Injection a vesicant?

Arzi 1000mg Injection is a potent vesicant (it is corrosive), and it should be carefully administered to avoid the risk of extravasation (leaking into the tissues).

Q. What is Arzi 1000mg Injection used for?

Arzi 1000mg Injection is used to treat skin cancer that has spread to other parts of the body (malignant melanoma), cancer of the white blood cell (Hodgkin’s lymphoma) and advanced adult soft tissue sarcomas (cancer of soft tissues such as muscles, tendons, fat, and blood vessels).

Q. How effective is Arzi 1000mg Injection?

Arzi 1000mg Injection is effective if taken at recommended dosage and duration as advised by your doctor.

Q. Does Arzi 1000mg Injection cause hair loss?

Yes, hair loss is a common side effect of Arzi 1000mg Injection.

In Malignant melanoma

Malignant melanoma is a type of skin cancer that develops in melanocytes, the cells that produce the pigment called melanin. Melanin is the pigment that gives the skin its color. Malignant melanoma is the most deadly and aggressive kind of skin cancer. Arzi 1000mg Injection sticks to the genetic code, called DNA,of the cancer cells and kills them . It also prevents their growth and further spread. This helps to treat the cancer.

In Hodgkin’s disease

Hodgkin’s disease is a type of lymphoma, which is a blood cancer that starts in the lymphatic system. The lymphatic system helps the immune system get rid of waste and fight infections. Arzi 1000mg Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. Follow your doctor’s instructions carefully.show moreshow less

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Loss of appetite

Decreased white blood cell count

Injection site pain

Vomiting

Nausea

Alcohol:CAUTION

Caution is advised when consuming alcohol with Arzi 1000mg Injection. Please consult your doctor.

Pregnancy:CONSULT YOUR DOCTOR

Arzi 1000mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding:CONSULT YOUR DOCTOR

Arzi 1000mg Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving:UNSAFE

Arzi 1000mg Injection may cause side effects which could affect your ability to drive.Arzi 1000mg Injection may influence the ability to drive because of its central nervous system side effects.

Kidney:CAUTION

Arzi 1000mg Injection should be used with caution in patients with kidney disease. Dose adjustment of Arzi 1000mg Injection may be needed. Please consult your doctor.

Liver:CAUTION

Arzi 1000mg Injection should be used with caution in patients with liver disease. Dose adjustment of Arzi 1000mg Injection may be needed. Please consult your doctor.

Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1686-87.

Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 942.

Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 346-47.

Dacarbazine citrate. Wedel, Germany: medac GmbH; 1997 . view

Drugs.com. Dacarbazine Pregnancy and Breastfeeding Warnings. view

Drugs and Lactation Database. Bethesda : National Library of Medicine ; 2006. Dacarbazine. . view