Bavencio Injection

Composition Avelumab (200mg)
Rx Prescription Required
Pack vial of 10 ml Injection
Storage Store in a refrigerator (2 – 8°C). Do not freeze.
Chemical Class Peptides
Action Class Other Anticancer Agents
Habbit Forming
Manufacturer Merck Ltd
Manufacturer address L-2, J.R. Complex, Gate No. 4, Village Mandoli, Delhi-110 093, India

Bavencio Injection is a medicine used for treatment of urinary bladder cancer that has metastasized (spread to other parts) or has reached the advanced stage in adults and children aged above 12 years. It restores those immune responses in the body that stop cancer growth.

Bavencio Injection is given as an injection by a healthcare professional. For it to be effective, complete the course of the medicine and do not discontinue even if you get better until the course is completed.

Some common side effects of this medicine include fatigue, nausea, diarrhea, decreased appetite, and muscle pain amongst others. These are usually mild and go away with time. However, if they persist or get worse, let the doctor know.

Before receiving the medicine, you should let your doctor if you have ever had an allergic reaction to any medicine. Also tell your doctor if you have any problems with your heart, kidneys, or liver. Some other medicines may react with this medicine, so let your doctor know of all the medication you are taking. Pregnant or breastfeeding should consult their doctors first before receiving this medicine.

Treatment of Urinary bladder cancer

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Bavencio Injection is a type of immunotherapy. It activates the body’s immune system to fight cancer cells. Avelumab targets and blocks a protein (PD-L1) found on the surface of certain immune cells. Blocking PD-L1 activates the immune cells to find and kill cancer cells.

Q: What if you forget to take Bavencio Injection?
A: If you miss a dose of Bavencio Injection, consult your doctor.

Do not receive any immunization or vaccination without your doctor’s approval while taking Bavencio Injection.

You may be at risk of infection, so try to avoid crowds or people with colds, and immediately report fever or any other signs of infection to your health care provider.

Inform your doctor immediately if you notice signs or symptoms of skin rash, itchy skin, a rash with tiny spots and bumps, reddening of the skin.

To reduce nausea, take anti-nausea medications as prescribed by your doctor, and eat small, frequent meals.

Use contraceptives, and do not conceive a child (get pregnant) while taking Bavencio Injection. Barrier methods of contraception, such as condoms, are recommended.

Avoid sun exposure. Wear SPF 15 (or higher) sunblock and protective clothing.

Do not drive or use machines after you have received Bavencio Injection since you might feel tired or dizzy.

In Treatment of Urinary bladder cancer

Bavencio Injection helps to treat urinary bladder cancer. It kills the cancer cells by stimulating the immune system of our body. It prevents progression of the disease to advanced stages of cancer and also reduces the chances of recurrence of the cancer. It is given as an injection by a doctor or nurse and should not be self-administered.

Fatigue

Musculoskeletal (bone, muscle or joint) pain

Diarrhea

Nausea

Infusion site reaction

Rash

Decreased appetite

Peripheral edema

Urinary tract infection

High blood pressure

Mucositis

Hand-foot syndrome

Voice change

Decreased level of thyroid hormones

Liver toxicity

Coughing up blood

Breathlessness

Abdominal pain

Headache

Alcohol:CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Bavencio Injection. Please consult your doctor.

Pregnancy:CONSULT YOUR DOCTOR

Bavencio Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding:CAUTION

Bavencio Injection should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.

Driving:SAFE

Bavencio Injection does not usually affect your ability to drive.

Kidney:SAFE IF PRESCRIBED

Bavencio Injection is safe to use in patients with kidney disease. No dose adjustment of Bavencio Injection is recommended.

Liver:SAFE IF PRESCRIBED

Bavencio Injection is safe to use in patients with liver disease. No dose adjustment of Bavencio Injection is recommended.

Bavencio (Avelumab) [Product Information]; 2021. [Accessed 16 Nov. 2022] (online) Available from: View
Avelumab [Prescribing Information]. Rockland, MA: : EMD Serono, Inc.; 2022. [Accessed 16 Nov. 2022] (online) Available from: View
Avelumab [Summary of Product Characteristics]. Modugno, Italy: Merck Serono S.p.A.; 2020. [Accessed 16 Nov. 2022] (online) Available from: View