Bdsure 11.25mg Injection

Composition Leuprolide (11.25mg)
Rx Prescription Required
Pack vial of 1 Injection
Storage Store in a refrigerator (2 – 8°C). Do not freeze.
Chemical Class GNRH Analogue
Action Class GNRH agonists/analogue
Habbit Forming No
Manufacturer BDR Pharmaceuticals Internationals Pvt
Manufacturer address 407-408, Sharda Chambers, New Marine Lines, Mumbai 400 020 (Maharashtra), New Marine Lines, Marine Lines, Mumbai, Maharashtra 400020

Bdsure 11.25mg Injection is given as an injection under the skin by a qualified medical professional.  Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Decreased libido, increased sweating, fatigue, muscle weakness, and hot flashes are some very common side effects of this medicine. The long-term use of medicine may cause weakened bones and a reduction in bone mineral density. You are advised to take vitamin D and calcium supplements while taking this medicine. It might cause menstrual periods to stop for a period of 7- 12 weeks, inform your doctor if menstrual bleeding continues even during the treatment.

Before taking this medicine, inform your doctor if you have a history of drinking alcohol, smoking, and osteoporosis. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Treatment of Prostate cancer
Treatment of Endometriosis
Treatment of Uterine fibroids
Treatment of Precocious puberty (premature puberty)

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Bdsure 11.25mg Injection reduces the amount of sex hormones (testosterone in men and estrogen in women). It works by decreasing the blood levels of testosterone in males. Bdsure 11.25mg Injection also acts by shutting off hormones made by the ovaries (female reproductive organs), so the estrogen (one of the hormones that causes females to have periods) level is lowered.

If you miss a dose of Bdsure 11.25mg Injection, please consult your doctor.

Bdsure 11.25mg Injection helps in the treatment of locally advanced or metastatic prostate cancer.

It may also be used to treat endometriosis and uterine fibroids.

It is given as an injection either under the skin or into a muscle.

It may cause dizziness and visual disturbances. Don’t drive or do anything that requires mental focus until you know how it affects you.

It will cause menstrual periods to stop. Periods will resume 7-12 weeks after the final injection. Consult your doctor if you experience menstrual bleed despite treatment. 

Use non-hormonal methods of contraception such as condoms to prevent pregnancy during treatment, as this medicine may be harmful to a developing baby.

Long term treatment may lead to bone loss and a higher risk of bone fractures, especially if you are a heavy drinker, a smoker, or have a family history of osteoporosis.

Q. Is Bdsure 11.25mg Injection a chemotherapy medicine?

No, Bdsure 11.25mg Injection is not a chemotherapy medicine. Bdsure 11.25mg Injection is a synthetic hormone analogue medicine which is used for the treatment of hormone-dependent conditions in men and women.

Q. Does Bdsure 11.25mg Injection stop periods?

Yes, the periods tend to stop while taking Bdsure 11.25mg Injection injections as this medicine alters the reproductive hormones in females. Sometimes, there can be vaginal bleeding in few cases. If this occurs, please contact your doctor to get yourself assessed and follow the direction of your doctor.

Q. Is Bdsure 11.25mg Injection a hormonal medicine and can it be given in pregnancy?

Yes, Bdsure 11.25mg Injection is a hormonal medicine which alters the reproductive hormones when given in females. This medication is not recommended for use in women who are or may become pregnant because this can harm the fetus in the womb. Using this medicine during pregnancy may also lead to abortion of the baby. Do inform your doctor if you are pregnant or are planning to get pregnant before starting this medication.

Q. Can taking Bdsure 11.25mg Injection affect my bones?

Yes, there are chances of Bdsure 11.25mg Injection affecting your bones. Using Bdsure 11.25mg Injection may cause a decrease in bone mineral density and make the bones weaker. In women, bone density should be assessed before starting the treatment. Special care and monitoring should be done in women with increased risk of osteoporosis. If at all needed, additional medicines may be given to prevent the development of osteoporosis in patients with decreased bone mineral density.

Q. Can Bdsure 11.25mg Injection cause diabetes or increased blood sugar?

Yes, Bdsure 11.25mg Injection may cause an increase in blood sugar levels, worsening the blood glucose control in patients with diabetes. It can even increase the risk of developing diabetes. Therefore, you must monitor the blood glucose and/or glycosylated hemoglobin (HbA1c) from time to time to keep a track of the glucose control and inform your doctor in case you develop any problem. Diabetic patients when prescribed this medication should monitor the sugar levels more frequently while taking this treatment.

In Treatment of Prostate cancer

Prostate gland is a small walnut-sized gland that produces a fluid called seminal fluid that nourishes and transports sperms in males. The most common symptom of prostate cancer is difficulty with urination, but sometimes there are no symptoms at all. Bdsure 11.25mg Injection decreases or stops the growth of cancer cells by decreasing the amount of testosterone (natural hormone in males) in men. This also relieves difficulty in passing urine and makes it easier for you to urinate.

In Treatment of Endometriosis

Endometriosis is a condition where tissue like the lining of the womb starts to grow in other places. The main symptoms include pain in your lower stomach or back, period pain, pain during and after sex, constipation, diarrhea and feeling sick. It can also make it difficult to get pregnant. Bdsure 11.25mg Injection works by preventing the lining of your womb and any endometriosis tissue from growing too quickly. This will help relieve the symptoms you may have. This medicine needs to be taken regularly to be effective and you may need other medicines or procedures to help control endometriosis.

In Treatment of Uterine fibroids

Uterine fibroids are non-cancerous growths of the uterus that often appear during childbearing years. Bdsure 11.25mg Injection helps control the symptoms associated with uterine fibroids such as excessive menstrual bleeding, lower back pain, and also reduces the size of the existing fibroids. It blocks the action of the enzyme responsible for the growth of the broids. As a result, they decrease in size and also stop growing further.

In Treatment of Precocious puberty (premature puberty)

When puberty (change of a child’s body to adult structure and size) begins before age 8 in girls and before age 9 in boys, it is considered precocious puberty. Bdsure 11.25mg Injection helps delay this early onset of adulthood and limits the onset of precocious puberty. However, this medicine is given by a doctor and should not be self-administered. Follow your doctor’s instructions carefully for the most benefit.show moreshow less

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Hot flashes

Injection site reaction

Bone pain

Erectile dysfunction

Muscle weakness

Fatigue

Increased sweating

Testicular atrophy

Decreased libido

Alcohol:CAUTION

Caution is advised when consuming alcohol with Bdsure 11.25mg Injection. Please consult your doctor.

Pregnancy:UNSAFE

Bdsure 11.25mg Injection is highly unsafe to use during pregnancy. Seek your doctor’s advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.

Breast feeding:CONSULT YOUR DOCTOR

Information regarding the use of Bdsure 11.25mg Injection during breastfeeding is not available. Please consult your doctor.

Driving:UNSAFE

Bdsure 11.25mg Injection may cause side effects which could affect your ability to drive.Do not drive or operate machinery if you experience drowsiness, dizziness or visual disturbances whilst being treated with Bdsure 11.25mg Injection.

Kidney:CONSULT YOUR DOCTOR

There is limited information available on the use of Bdsure 11.25mg Injection in patients with kidney disease. Please consult your doctor.

Liver:CONSULT YOUR DOCTOR

There is limited information available on the use of Bdsure 11.25mg Injection in patients with liver disease. Please consult your doctor.

Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 959.

Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 787-88.

Leuprorelin acetate. Wooburn Green, High Wycombe: Takeda UK Ltd.; 2011 . view

Leuprolide Leuprorelin acetate. Fort Collins: TOLMAR Inc.; 2002 . view