Berirab P Injection

Berirab P Injection is given as an injection by a doctor or nurse. It must always be used in combination with a rabies vaccine. Post-exposure prophylaxis consists of a regimen of one dose of immunoglobulin and full courses of rabies vaccination. This should be given as soon as possible after exposure. Both active (vaccine) and passive immunization (Immunoglobulin) prevent the rabies virus from infiltrating the central nervous system, but become ineffective once the virus has crossed into the central nervous system. Berirab P Injection is administered only once in a lifetime.

The most common side effects include pain, anaphylactic reaction, angioedema (swelling of deeper layers of skin), injection site stiffness, soreness, and tenderness. They do not normally last very long. Sitting or lying down can sometimes help. Consult your doctor if any of the side effects persist or worry you.

Before having the injection, you should tell your doctor if you’ve ever had an allergic reaction to an immunoglobulin. Some other medicines may react with the human rabies immunoglobulin so talk to your doctor about other medications you are taking as well. You should consult your doctor first if you are pregnant or breastfeeding.

Prevention of Rabies

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Berirab P Injection is an inactivated vaccine (made from a dead virus). It helps develop immunity by forming antibodies, which are proteins that protect against infection caused by viruses present in the vaccine.

If you miss a dose of Berirab P Injection, please consult your doctor.

Berirab P Injection protects you against rabies after you have been bitten, scratched, or injured by a suspected animal with rabies.

It is given with the first dose of rabies vaccine, or not more than 7 days after the scratch or injury.

It is given by injection around the wound and into the muscle at the side of the thigh (intramuscular).

Q. What is Berirab P Injection? What is it used for?

Berirab P Injection is a solution containing a large amount of rabies antibodies. It is used to provide protection against rabies. It is given either along with the first dose of anti-rabies vaccine(ARV) or not more than 7 days later.

Q. How effective is Berirab P Injection?

Rabies is a 100% preventable disease. Proper wound management and simultaneous administration of Berirab P Injection combined with anti-rabies vaccine (ARV) is almost invariably effective in preventing rabies, even after high-risk exposure.

Q. Is Berirab P Injection necessary?

Berirab P Injection is not required for patients who have previously received a complete vaccination series of rabies.

Q. Is Berirab P Injection painful?

Whether Berirab P Injection is painful or not depends on your pain tolerance. During your initial treatment, a healthcare professional will put Berirab P Injection in the area where you were bitten. This can be painful. Therefore, a relatively greater amount of Berirab P Injection may be required to be placed in and around the wound site to ease out your pain and treat infection.

Q. Is Equine Rabies Immunoglobulin better than Berirab P Injection?

Equine Rabies Immunoglobulin is more economical as compared to Berirab P Injection i.e., human rabies immunoglobulin (HRIG). Hence, it is more affordable to patients in developing countries, like India. However, Equine Rabies Immunoglobulin has a high potential to cause anaphylaxis (a severe, potentially life-threatening allergic reaction), serum sickness and other allergic reactions and thus physicians are hesitant to use it.

In Prevention of Rabies

Rabies is a serious disease caused by the rabies virus transmitted through the saliva of infected animals. Berirab P Injection is used along with the rabies vaccine to prevent infection caused by the rabies virus. It works by giving your body the antibodies it needs to protect it against the rabies virus. This medicine is administered only once in a lifetime and should be used only in individuals who have never received the rabies vaccine before. It is to be administered only by or under the supervision of your doctor. You should not self administer this medicine.

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Tenderness

Soreness

Injection site stiffness

Angioedema (swelling of deeper layers of skin)

Anaphylactic reaction

Pain

Nephrotic syndrome

Alcohol:CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Berirab P Injection. Please consult your doctor.

Pregnancy:SAFE IF PRESCRIBED

Berirab P Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Breast feeding:CAUTION

Berirab P Injection should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.

Driving:SAFE

Berirab P Injection does not usually affect your ability to drive.

Kidney:SAFE IF PRESCRIBED

Berirab P Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Berirab P Injection may not be needed in these patients. Please consult your doctor.

Liver:SAFE IF PRESCRIBED

Berirab P Injection is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Berirab P Injection may not be needed in these patients. Please consult your doctor.

Human Rabies Immunoglobulin. Elstree, Hertfordshire; Bio Products Laboratory Limited; 1992 . view

Drugs.com. Human Rabies Immunoglobulin. view

Human Rabies Immunoglobulin. Marburg, Germany: Novartis Vaccines and Diagnostics GmbH; 2005 . view