Bio-Azapin 50mg Tablet

Composition Azathioprine (50mg)
Rx Prescription Required
Pack strip of 10 tablets
Storage Store below 30°C
Chemical Class Nucleoside Analog, and Purines
Action Class Immunosuppressant- Purine analogs
Habbit Forming
Manufacturer Bios Labs Pvt Ltd
Manufacturer address 206 Marurti Nandan Complex Rajkot Gujrat

Bio-Azapin 50mg Tablet belongs to a group of medicines called immunosuppressants. It is used with other medicines to prevent your body from rejecting an organ (such as a kidney, heart, or liver) after a transplant. It is also used in the treatment of rheumatoid arthritis.

The dose of Bio-Azapin 50mg Tablet and how often you need to take it will depend on whether you have had a transplant or are being treated for rheumatoid arthritis. Follow your doctor’s instructions on this. You can take it with or without food. Take the medicine regularly to get the most benefit and keep taking it even if you feel well. If you stop taking it, the risk of organ rejection may increase, and if you’re using it for rheumatoid arthritis, your symptoms may not improve.

The most common side effects of Bio-Azapin 50mg Tablet are nausea and reduction of white blood cells and bone marrow function. Because it suppresses your immune system, you may catch infections easily. There is also an increased risk of developing some cancers for this reason. You should ask your doctor about side effects that may require urgent medical attention.

Bio-Azapin 50mg Tablet can cause birth defects and miscarriages, so do not take it if you are pregnant, planning to become pregnant, or breastfeeding. You should talk to your doctor before taking this medicine if you have any signs of infection or any unexpected bruising or bleeding. Let your doctor also know what other medications you are taking, as some may interact with this medicine and affect the way it works. You will have regular tests to check for any changes in the number of your blood cells.

Treatment of Rheumatoid arthritis

Prevention of organ rejection in transplant patients

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Bio-Azapin 50mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

Bio-Azapin 50mg Tablet is an immunosuppressant. It reduces the action of the body’s defense system (the immune system) and prevents rejection of the transplanted organ. It also blocks the action of certain chemical messengers that are responsible for inflammation, swelling, and redness associated with certain joint diseases.

Q: What if you forget to take Bio-Azapin Tablet?
A: If you miss a dose of Bio-Azapin 50mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

You may have to take additional medications along with Bio-Azapin 50mg Tablet for better relief of symptoms.

Avoid contact with people who have a cold, flu, or other contagious illness. Notify your doctor if you have any signs of infection, such as a fever or sore throat.

Inform your doctor if you are pregnant, planning to conceive, or breastfeeding.

Q. What is Bio-Azapin 50mg Tablet prescribed for? How does it work?

Bio-Azapin 50mg Tablet is an immunosuppressant, which means that it acts by suppressing the immune defense system of the body. Your immune defense system helps to protect you against infections. However, sometimes your immune defense system can become overactive and can cause illness. Bio-Azapin 50mg Tablet is used in combination with other medicines to treat the conditions caused by this abnormal activity of the immune system. It is used to prevent the rejection of transplanted organs, like the kidney, heart, or liver. It is also used to treat rheumatoid arthritis.

Q. How long do I need to take Bio-Azapin 50mg Tablet?

The duration varies from person to person, as it is prescribed depending on the patient’s medical condition.

Q. Is breastfeeding safe during Bio-Azapin 50mg Tablet treatment?

No, breastfeeding should be avoided while on Bio-Azapin 50mg Tablet, since it may harm the baby and cause serious side effects.

Q. I have just started taking Bio-Azapin 50mg Tablet. What are the long-term side effects? Is there anything I should be looking out for?

Being an immunosuppressant, Bio-Azapin 50mg Tablet can increase the chances of severe infections and decrease blood cell counts, and malignancy. You should inform your doctor immediately if you notice any infection or fever, unexpected bruising or bleeding, black tarry stools, or blood in the urine or stools. Let your doctor know if you notice any new skin sore or lump, new marks on the skin, or any change in the marks that were previously present.

Q. Do I need any special tests while I am on Bio-Azapin 50mg Tablet?

Bio-Azapin 50mg Tablet reduces the production of white blood cells, making you more vulnerable to infections, and can sometimes affect the liver. These side effects can be monitored by regular blood tests. Therefore, during the first 8 weeks of the treatment, your doctor may recommend weekly blood tests to monitor complete blood counts, including platelet counts. The frequency can later be reduced to monthly or at least once every 3 months.

Q. Can Bio-Azapin 50mg Tablet cause cancer?

Bio-Azapin 50mg Tablet may increase the chance of developing certain cancers like skin cancer, cancer of the lymph system (lymphoma), cancer of soft tissues (sarcomas), and cervical cancer. To prevent the risk of skin cancer, avoid prolonged exposure to sunlight and wear protective clothing, sunglasses, and sunscreen. Tell your doctor immediately if you notice any changes in your skin or any lumps or masses anywhere on your body.

In Treatment of Rheumatoid arthritis

Bio-Azapin 50mg Tablet works by blocking the action of some chemicals which cause inflammation. It can help reduce pain, stiffness, and swelling in your joints and slow down the progression of bone and joint damage. This will help you do normal daily activities more easily and thus improve your quality of life. This medicine should be taken at the same time each day to get maximum benefits. Keep taking it even if you feel well because it is preventing future harm as well as improving your symptoms.

Viral infection

Fungal infection

Bacterial infection

Decreased white blood cell count

Bone marrow disorder

Increased bleeding tendency

Nausea

Alcohol:CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Bio-Azapin 50mg Tablet. Please consult your doctor.

Pregnancy:CONSULT YOUR DOCTOR

Bio-Azapin 50mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding:UNSAFE

Bio-Azapin 50mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving:CONSULT YOUR DOCTOR

It is not known whether Bio-Azapin 50mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

Kidney:CAUTION

Bio-Azapin 50mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Bio-Azapin 50mg Tablet may be needed. Please consult your doctor.Use of Bio-Azapin 50mg Tablet is not recommended in patients with serious kidney disease.

Liver:CAUTION

Bio-Azapin 50mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Bio-Azapin 50mg Tablet may be needed. Please consult your doctor.Use of Bio-Azapin 50mg Tablet is not recommended in patients with severe liver disease. Regular monitoring of liver function tests is advisable while you are taking this medicine.

Krensky AM, Bennett WM, Vincenti F. Immunosuppressants, Tolerogens, and Immunostimulants. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 1013-14.
Furst DE, Ulrich RW, Varkey-Altamirano C. Nonsteroidal Anti-Inflammatory Drugs, Disease Modifying Antirheumatic Drugs, Nonopioids Analgesics, & Drugs Used in Gout. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 629-30.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 113-15.
Azathioprine [Prescribing Information]. San Diego, California: Prometheus Laboratories Inc.; 2014. [Accessed 06 Apr. 2019] (online) Available from: View
Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 03 Apr. 2019] (online) Available from: View
Azathioprine [Product Information]. Parsippany, NJ: Ascend Laboratories, LLC; 2021. [Accessed 09 Jun, 2023] (online) Available from: View
Mohammadi O, Kassim TA. Azathioprine. [Updated 2023 May 1]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023. [Accessed 09 Jun, 2023] (online) Available from: View
Azathioprine [EMC Label]. Luton, UK: Tillomed Laboratories Ltd.; 2025. [Accessed 25 Feb. 2025] (online) Available from: View