Composition Nimotuzumab (50mg)
Rx Prescription Required
Pack vial of 1 Injection
Storage Store in a refrigerator (2 – 8ยฐC). Do not freeze.
Chemical Class Monoclonal antibody (mAb)
Action Class EGFR (ErbB1 or HER1) inhibitors- Monoclonal antibody
Habbit Forming No
Manufacturer Biocon
Manufacturer address 20th KM, Hosur Road, Electronic City, Bangalore, India – 560 100

Biomab 50mg Injection
Biomab 50mg Injection is used in the treatment of head and neck cancer and cancer of colon and rectum. It helps to mark the cancer cells for destruction by the body’s immune system.
Basic Info
Description
Biomab 50mg Injection is given as an injection under the supervision of a doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. Do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include weakness, vomiting, dizziness, and diarrhea. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. Inform your doctor if you experience sudden difficulty in breathing, shortness of breath, fever, or chills. Regular blood tests are required to check your blood cells along with heart, liver, and electrolyte levels.
Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Uses
Head and neck cancer
Cancer of colon and rectum
How To Use
Your doctor or nurse will give you this medicine. Kindly do not self administer.
MOA
Biomab 50mg Injection is a monoclonal antibody that specifically binds to receptors on cancer cells. Thus it flags the cancer cells for destruction by the body’s immune system.
What If
If you miss a dose of Biomab 50mg Injection, please consult your doctor.
Drug Tips
Biomab 50mg Injection is given as in injection or infusion under the supervision of a doctor only.
Do not skip any dose and complete the course as suggested by your doctor.
Use an effective method of birth control to avoid pregnancy while taking this medication.
Your doctor may get regular blood tests done to monitor your blood cell count (CBC), electrolyte levels. liver and kidney function.
It is advisable to drink plenty of water to stay hydrated while taking this medicine.
Inform your doctor if you experience chills, fever, shortness of breath and difficulty breathing during the treatment.ย
Faqs
Information not available at the moment. Please check back later.
Benifits
In Head and neck cancer
Head and neck cancer includes cancer of the mouth, nose, sinuses or throat. Biomab 50mg Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol or smoking while having this treatment and drink plenty of water to stay hydrated.
In Cancer of colon and rectum
Cancer of the colon and rectum, also known as colorectal cancer (CRC) or bowel cancer, is the development of cancer from two parts of the large intestine, namely, the colon or rectum. In this type of cancer, the person may notice symptoms such as blood in the stool, a change in bowel movements, weight loss, and fatigue. Biomab 50mg Injection treats and also lowers the risk of developing further cancerous growths (polyps) and bowel cancer. It kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is an effective medicine, but has some bothersome side effects. Consult your doctor if you have any concerns.show moreshow less
Side Effects
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if youโre worried about them
Diarrhea
Blood in urine
Dizziness
Vomiting
Weakness
Safety Profile
Alcohol:CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Biomab 50mg Injection. Please consult your doctor.
Pregnancy:CONSULT YOUR DOCTOR
Biomab 50mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding:CONSULT YOUR DOCTOR
Information regarding the use of Biomab 50mg Injection during breastfeeding is not available. Please consult your doctor.
Driving:CONSULT YOUR DOCTOR
It is not known whether Biomab 50mg Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney:CONSULT YOUR DOCTOR
There is limited information available on the use of Biomab 50mg Injection in patients with kidney disease. Please consult your doctor.
Liver:CONSULT YOUR DOCTOR
There is limited information available on the use of Biomab 50mg Injection in patients with liver disease. Please consult your doctor.
Refferences
Ramakrishnan MS, Eswaraiah A, Crombet T, et al. Nimotuzumab, a promising therapeutic monoclonal for treatment of tumors of epithelial origin. MAbs. 2009;1:41-8. view

