Biopanib 200mg Tablet

Biopanib 200mg Tablet is a protein kinase inhibitor used in the treatment of kidney cancer and soft tissue sarcoma.

Biopanib 200mg Tablet should be taken on an empty stomach, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Diarrhea and high blood pressure are the most common side effects of this medicine. Doctor may advise for regular monitoring of your blood pressure while on treatment. Drink plenty of fluids to overcome diarrhea or consult with your doctor if it bothers you. This medicine may reduce the number of blood cells in your blood, thereby, increasing the susceptibility to infections. Hence, inform your doctor if you experience fever, flu-like symptoms and shortness of breath.

Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Kidney cancer

Soft tissue sarcoma

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Biopanib 200mg Tablet is to be taken empty stomach.

Biopanib 200mg Tablet is an anti-cancer medication. It works by binding and inhibiting the enzyme receptors (tyrosine kinase) that are responsible for the proliferation of the cancerous cells. It also restricts the growth of new blood vessels within the tumor. This is how it works against cancer.

Q: What if you forget to take this medicine?
A:

Q. Is Biopanib 200mg Tablet a chemotherapy medicine?

Biopanib 200mg Tablet is not a conventional chemotherapy medicine. It belongs to a class of medicine called a protein kinase inhibitor. Biopanib 200mg Tablet works by preventing the activity of proteins that are involved in the growth and spread of cancer cells.

Q. How should I take Biopanib 200mg Tablet?

Biopanib 200mg Tablet should be taken orally by mouth once a day or as directed by your doctor. Swallow the tablets whole with water, do not break or crush the tablets. This affects the way the medicine is absorbed and may increase the chance of side effects.

Q. Can Biopanib 200mg Tablet be taken with food?

Biopanib 200mg Tablet should be taken on an empty stomach, at least 1 hour before or 2 hours after food. If it is taken with food, the dosage may need to be increased. Doing this will in turn cause more side effects.

Q. How will I know if Biopanib 200mg Tablet is helping me?

The duration for which you have to continue taking Biopanib 200mg Tablet varies from person to person. The doctor monitors you closely and will be able to better estimate how long the medicine needs to be taken. Do not stop taking it without telling your doctor. It needs to be taken as long as it is effective and you can tolerate it.

Q. Are there any food restrictions while I’m taking Biopanib 200mg Tablet?

Yes, it is best to avoid grapefruit and grapefruit juice while on Biopanib 200mg Tablet, as it may affect how the medicine works in your body. Ask your doctor about any additional foods you should avoid.

Q. How long I have to take Biopanib 200mg Tablet?

The duration for which you have to continue taking Biopanib 200mg Tablet varies from person to person. The doctor monitors you closely and will be able to better estimate how long the medicine needs to be taken. Do not stop taking it without telling your doctor. It needs to be taken as long as it is effective and you can tolerate it.

Q. What is the most important information I need to know about Biopanib 200mg Tablet?

Biopanib 200mg Tablet may cause severe or life-threatening liver damage. Inform your doctor if you have or had liver disease. If you experience any of the following symptoms such as discoloration of the skin or eyes (yellowing), dark urine, extreme tiredness, nausea, vomiting, loss of appetite, pain in the upper right part of the stomach, or unusual bleeding or bruising, call your doctor immediately. Your doctor may ask you to take some lab tests before you start taking Votrient. After you start taking Votrient, you may need to take those lab tests at weeks 3, 5, 7 and 9 and then at months 3 and 4. Your doctor may also prescribe additional tests if necessary. Periodic testing should then continue after 4 months.

Headache

Nausea

Vomiting

Musculoskeletal (bone, muscle or joint) pain

Fatigue

Change in color of hair

Diarrhea

High blood pressure

Decreased appetite

Weight loss

Taste change

Abnormal skin pigmentation

Hair discoloration

Tumor pain

Breathlessness

Alcohol:CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Biopanib 200mg Tablet. Please consult your doctor.

Pregnancy:CONSULT YOUR DOCTOR

Biopanib 200mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding:UNSAFE

Biopanib 200mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving:UNSAFE

Biopanib 200mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney:SAFE IF PRESCRIBED

Biopanib 200mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Biopanib 200mg Tablet is recommended.

Liver:CAUTION

Biopanib 200mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Biopanib 200mg Tablet may be needed. Please consult your doctor.Use of Biopanib 200mg Tablet is not advised in patients with moderate to severe liver disease.

Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1072-73.
Pazopanib. Research Triangle Park, North Carolina: GlaxoSmithKline; 2009 [revised Apr. 2012]. [Accessed 24 Jan. 2019] (online) Available from: View
Central Drugs Standard Control Organisation (CDSCO). [Accessed 26 Mar. 2019] (online) Available from: View