Bleostar Injection

Composition Bleomycin (15IU)
Rx Prescription Required
Pack vial of 1 Injection
Storage Store in a refrigerator (2 – 8°C). Do not freeze.
Chemical Class Antitumor Antibiotics
Action Class Cytotoxic Alkaloids
Habbit Forming
Manufacturer Chandra Bhagat Pharma Pvt Ltd
Manufacturer address 501, The Bureau, R C MARG, Nr.Chembur Naka, Chembur East, Mumbai – 400071

Bleostar Injection is a medicine used for treatment of cancer in various parts of the body such as cervical, cancer of the mouth, nasopharynx and paranasal sinuses, larynx, esophagus, and skin. It works by interfering with the growth of cancer cells, which are eventually destroyed.

Bleostar Injection may be used alone or with other medicines as part of combination therapy. It is given under the supervision of a healthcare professional and should not be self-administered. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. You should avoid drinking alcohol as it may increase your risk of liver damage.

The most common side effects of this medicine include fever, loss of appetite, loss of hair, weight loss, nausea, inflammation of the lungs (interstitial pneumonia), shortness of breath or cough. If they do not go away or get worse, tell your doctor. There may be ways of preventing or reducing these effects. It is very strong medicine and some people may develop serious side effects while taking it. This medicine may lower your ability to fight infections and lead to problems with your blood, liver or kidneys. Your doctor will advise you regular blood tests to check for these.

Before taking it, tell your doctor if you have stomach, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. It may harm your baby. You and your partner should avoid becoming pregnant or fathering a child for several months after your treatment with it has stopped. Your doctor may perform several tests such as blood tests, X-rays and physical examinations both before and during treatment with this medicine.

Skin cancer

Cancer of mouth, nasopharynx and paranasal sinuses, larynx, oesophagus

Cervical cancer

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Bleostar Injection is an anti-cancer medication. It works by damaging the genetic material (DNA) of the cancer cells and stops their growth and multiplication.

Q: What if you forget to take this medicine?
A:

Bleostar Injection is given as an injection into the veins, muscles or under the skin by the healthcare provider.

Do not skip any dose and complete the course as suggested by your doctor.

Use an effective method of birth control to avoid pregnancy while taking this medication.

You may need to have blood tests to monitor your blood cells, liver function and kidney function during treatment.

Inform your doctor immediately if you experience coughing, shortness of breath and cracking sound while breathing.

Q. What does Bleostar Injection treat?

Bleostar Injection is used to treat squamous cell cancers, certain types of blood cancers, skin cancers and cancer of the thyroid, bladder, lungs, abdomen or genitals.

Q. Does Bleostar Injection cause pulmonary fibrosis, nausea or hair loss?

Yes. Bleostar Injection may cause pulmonary fibrosis, nausea and hair loss. If you notice any such symptoms, please consult your doctor.

Q. How does Bleostar Injection cause pulmonary fibrosis?

Pulmonary fibrosis (scarring of the tissue of the lungs) is one of the side effects of Bleostar Injection. It is reportedly caused by lack of an enzyme that metabolises Bleostar Injection in the lungs.

In Cervical cancer

Bleostar Injection is an anti-cancer medicine that is used to kill cancerous cells in various kinds of cancer such as cervical cancer, cancer of mouth, nasopharynx and paranasal sinuses, larynx, oesophagus and skin cancer. It may be given alone or in combination with other medicines. It has a lot of side effects and you must discuss the risks and benefits with your doctor before starting treatment with this medicine. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

Fever

Hair loss

Interstitial pneumonia

Loss of appetite

Low blood platelets

Nail discoloration

Nausea

Pulmonary fibrosis

Rigors

Scratch dermatitis

Skin pigmentation

Stomatitis (Inflammation of the mouth)

Vomiting

Weight loss

Alcohol:CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Bleostar Injection. Please consult your doctor.

Pregnancy:CONSULT YOUR DOCTOR

Bleostar Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding:CONSULT YOUR DOCTOR

Bleostar Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving:UNSAFE

Bleostar Injection may cause side effects which could affect your ability to drive.As with $med_name, few people have reported that they feel tired or weak after the treatment so it may affect your driving ability.

Kidney:CAUTION

Bleostar Injection should be used with caution in patients with kidney disease. Dose adjustment of Bleostar Injection may be needed. Please consult your doctor.

Liver:SAFE IF PRESCRIBED

Bleostar Injection is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Bleostar Injection may not be needed in these patients. Please consult your doctor.

Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1716-18.
Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 952-53.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 149-50.
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Bleomycin. [Updated 2018 Dec 3]. [Accessed 18 Feb. 2020] (online) Available from: View