Bonotiode Injection

Composition Teriparatide (750mcg)
Rx Prescription Required
Pack penfill of 3 ml Injection
Storage Store in a refrigerator (2 – 8°C). Do not freeze.
Chemical Class Parathyroid Hormone Analogs
Action Class Bone formation stimulator -PTH analogue
Habbit Forming No
Manufacturer LG Lifesciences
Manufacturer address LG Life Sciences India Pvt. Ltd., Unit No. 201, 2nd Floor, BPTP Park Centra, Sec 30, Gurgaon 122001, Haryana, India

Bonotiode Injection should be injected under the skin or given by a healthcare professional. You should use it regularly and at the same time each day to get the maximum benefit from it. Usually, it is recommended to take it for a maximum period of 2 years. However, follow the doctor’s advice and complete the course even if you feel better. It should be stored in the refrigerator at a temperature of  2°C to 8°C.

Some common side effects of this medicine include joint pain, injection site reactions (such as pain, swelling, and redness) and leg cramps. consult with your doctor if any of these bother you or do not go away. 

Before taking this medicine, let your doctor know if you have kidney stones or any other kidney problems, as it can cause an increase in the amount of calcium in blood or urine. Pregnant and breastfeeding mothers should also consult with their doctors before taking this medicine. Your doctor may advise a bone scan to monitor the progress of your treatment.

Osteoporosis

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Bonotiode Injection is a synthetic form of a natural human hormone called parathyroid hormone (PTH). It works by increasing the number and activity of bone-forming cells (osteoblasts). This strengthens the bones and minimizes the risk of fractures.

If you miss a dose of Bonotiode Injection, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Bonotiode Injection should be injected every day under the skin (subcutaneous injection) of the thigh or abdomen.

Do not take it for more than 2 years.

You may have low blood pressure and dizziness during the initial few days.

If you feel dizzy (light-headed) after injection, sit or lie down until you feel better.

Tell your doctor immediately if you experience nausea, vomiting, constipation, low energy, or muscle weakness. These may be signs of high calcium levels in your blood.

Tell your doctor if you are breastfeeding, pregnant or plan to become pregnant.

Q. Is Bonotiode Injection a steroid?

No, Bonotiode Injection is not a steroid. However, this medicine may be used to treat osteoporosis caused by long-term use of steroids. Generally, this medicine is used to treat osteoporosis in women of postmenopausal age group and in men who have increased risk of fracture.

Q. Can I take this medication in long term for osteoporosis?

Bonotiode Injection should not be taken for longer than 2-year course. It is important to inform the doctor if you have taken this medication in the past, as you should not receive more than one treatment of 24 months course more than once in your lifetime.

Q. How is Bonotiode Injection stored at home?

Always keep this medicine stored in a refrigerator at a temperature of about 2°C to 8°C. Be cautious, the temperature should not decrease further as freezing may cause the medicine to get damaged and can lead to loss of activity. Therefore, avoid placing the Bonotiode Injection pens close to the ice compartment of the refrigerator. If properly stored this medication can be used up to 28 days after the first injection. If the pen is not empty within 28 days please discard it safely.

Q. Who should not use Bonotiode Injection?

The doctor will decide whether the medicine is required for a patient or not. There are few conditions in which the use of Bonotiode Injection should be avoided such as in patients with kidney impairment, Paget’s disease, any type of bone cancers or unexplained high levels of serum calcium. It should also be avoided by children, young adult or growing age, pregnant or lactating females. Hence, before starting the medication inform the doctor about any medical condition and the medication you are taking. This will help the doctor to design a proper therapy for you.

In Osteoporosis

Osteoporosis is a common condition that weakens bones, making them fragile and more likely to break. Bonotiode Injection helps treat osteoporosis in men as well as in women after menopause. It slows down the rate at which bone is broken down in your body. This maintains bone density and reduces your risk of breaking a bone. The injection is given by a doctor or nurse and should not be self-administered. You can help improve the strength of your bones by doing regular exercise (especially weight-bearing exercise), eating healthy foods containing calcium and Vitamin D and reducing your consumption of alcohol and tobacco. Supplements of calcium and Vitamin D3 are also effective.

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Leg cramps

Nausea

Injection site reactions (pain, swelling, redness)

Joint pain

Alcohol:CAUTION

Caution is advised when consuming alcohol with Bonotiode Injection. Please consult your doctor.

Pregnancy:CONSULT YOUR DOCTOR

Bonotiode Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding:CONSULT YOUR DOCTOR

Information regarding the use of Bonotiode Injection during breastfeeding is not available. Please consult your doctor.

Driving:UNSAFE

Bonotiode Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney:CAUTION

Bonotiode Injection should be used with caution in patients with kidney disease. Dose adjustment of Bonotiode Injection may be needed. Please consult your doctor.Use of Bonotiode Injection is not recommended in patients with severe kidney disease.

Liver:CONSULT YOUR DOCTOR

There is limited information available on the use of Bonotiode Injection in patients with liver disease. Please consult your doctor.

Bikle DD. Agents That Affects Bone Mineral Homoestasis. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 766.

Friedman PA. Agents Affecting Mineral Ion Homeostasis and Bone Turnover. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1300

Teriparatide. Indianapolis, Indiana: Lilly France; 2008. view

Central Drugs Standard Control Organisation . view