Brexclob-GM Cream

Brexclob-GM Cream is a combination medicine used in the treatment of various types of skin infections. It minimizes symptoms of inflammation such as redness, swelling, and itching by acting against the infection-causing microorganisms.

Brexclob-GM Cream is only meant for external use and should be used as advised by your doctor. A thin layer of the medicine should be applied only to the affected areas of the skin with clean and dry hands. If it gets into your eyes, nose, mouth, or vagina rinse with water. It may take several days to weeks for your symptoms to improve, but you should keep using this medicine regularly. The course of the treatment should be completed to ensure better efficacy of the medicine. If your condition does not improve or gets worse, you should talk to your doctor.The most common side effect of this medicine includes itching, dryness, redness, and burning sensation at the application site. These are usually self-limiting. Serious side effects are rare. You must consult the doctor if you experience any allergic reaction (rashes, itching, swelling, shortness of breath, etc.).Before taking this medicine, it is important to tell your doctor if you are taking or have recently taken any other medicines for the same disease or other diseases. Pregnant and breastfeeding women should take this medicine with proper consultation and caution. If you are a known allergic to the medicine, you must refrain from using this medicine. You should consult the doctor about prescribing an alternative medicine for your condition.

Treatment of Skin infections

This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the cream. Wash your hands after applying, unless hands are the affected area.

Brexclob-GM Cream is a combination of three medicines: Clobetasol, Miconazole and Neomycin, which treats skin infections. Clobetasol is a steroid medicine. It blocks the production of certain chemical messengers (prostaglandins) that make the skin red, swollen and itchy. Miconazole is an antifungal which stops the growth of fungi by preventing them from forming their own protective covering. Neomycin is an antibiotic. It stops bacterial growth by preventing the synthesis of essential proteins required by the bacteria to carry out vital functions.

If you miss a dose of Brexclob-GM Cream, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Brexclob-GM Cream must be applied as a thin layer on the affected area as prescribed by your doctor.

Do not use this medicine more often or for longer than advised by your doctor.

Before each application, wash the affected area with soap and water and dry well. 

Avoid getting it in the eyes, mouth or nose. Rinse with cold water if you accidentally get it in these areas.

Do not cover the area being treated with airtight dressings such as bandages unless directed by a doctor, as this may increase the risk of side effects.

Inform your doctor if the treated skin area does not improve after 2-4 weeks of treatment.

Q. Can I stop using Brexclob-GM Cream when my symptoms are relieved?

No, do not stop using Brexclob-GM Cream without consulting your doctor. Use Brexclob-GM Cream in the dose and duration prescribed by the doctor. Usually, your condition will improve within a few days. If the condition worsens or does not improve within seven days, treatment and diagnosis should be re-evaluated. However, if the treatment is recommended to be continued for a longer duration, it should be done under medical supervision.

Q. What precautions should I take while using Brexclob-GM Cream?

Brexclob-GM Cream should be used carefully only over the affected area, avoiding the medicine from getting into the eyes. Do not apply a bandage or dressing on the area being treated, as this will increase the absorption of the medicine and increase the risk of side effects. This medicine should only be used for the condition it is prescribed for. Do not use it for any other condition without consulting your doctor. Do not give it to other people even if their condition appears to be the same.

Q. How to use Brexclob-GM Cream?

Brexclob-GM Cream should be used as advised by the doctor or as per the instructions on the label of the medicine. Apply a thin layer of it to cover the affected areas. The dose would depend on the condition for which it is prescribed. Wash your hands after using Brexclob-GM Cream unless it is used for treating infection of the hands. Avoid contact with the eyes.

Q. What would happen if I use a higher than the recommended dose of Brexclob-GM Cream for long periods?

Brexclob-GM Cream should be used only for the dose and duration as advised by the doctor. This medicine contains a steroid, clobetasol which when used in higher doses and for longer periods can get absorbed in the blood and cause adrenal suppression and Cushing’s syndrome. It can cause weight gain, high blood pressure and rounding of the face. Its application can cause a change in color of skin at the site of application. Veins beneath the skin become visible due to the thinning and weakening of the skin. There could be an increased hair growth. If you experience an increased severity of your symptoms, please consult your doctor for re-evaluation.

Q. What are the contraindications associated with the use of Brexclob-GM Cream?

Use of Brexclob-GM Cream is considered to be harmful for patients with known allergy to any of the components or excipients of this medicine. Its use should be avoided in case of any primary infected skin lesions caused by infection with fungi, bacteria or yeast, viral infections (herpes or chickenpox). Its use should also be avoided in treating acne or rosacea. Consult your doctor before using it for any condition.

Q. What are the instructions for the storage of Brexclob-GM Cream?

Brexclob-GM Cream should be stored at or below room temperature, away from direct heat or sunlight. Do not freeze. Also, keep it away from the reach of pets and children.

In Treatment of Skin infections

Brexclob-GM Cream is a combination of medicines used to treat skin infections caused by microorganisms such as bacteria and fungi. It kills and stops the growth of infection-causing microorganisms, thereby clearing the infection and relieving the symptoms. It also blocks the release of chemicals that cause symptoms such as itching, redness, and swelling. Therefore this medicine relieves the inflammation due to these infections.You should use Brexclob-GM Cream for as long as it is prescribed, even if your symptoms disappear, otherwise they may come back. Depending on the type of infection you are treating, this may be several weeks. Even after your infection is completely cured, you may have to apply it occasionally to prevent the symptoms from returning.

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Thinning of skin

Application site reactions (burning, irritation, itching and redness)

Alcohol:

No interaction found/established

Pregnancy:CONSULT YOUR DOCTOR

Brexclob-GM Cream may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding:SAFE IF PRESCRIBED

Brexclob-GM Cream is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Driving:

No interaction found/established

Kidney:

No interaction found/established

Liver:

No interaction found/established

Clobetasol Propionate + Neomycin Sulphate + Miconazole Nitrate. GlaxoSmithKline; 25 May 2016. view

Miconazole Nitrate + Clobetasol Propionate + Neomycin Sulphate Creams. view

Clobetasol. Uxbridge, Middlesex: GlaxoSmithKline UK; 1993 . view

Miconazole. Schorndorf, Germany: Catalent Germany Schorndorf; 1974 . view

PubChem. Neomycin. view

Clobetasol. Melville, New York: Fougera Pharmaceuticals Inc.; 1994. view

ScienceDirect. Miconazole. view

ScienceDirect. Neomycin. view