Composition Brinzolamide (1%)
Rx Prescription Required
Pack bottle of 5 ml Ophthalmic Suspension
Storage Store in a refrigerator (2 – 8ยฐC). Do not freeze.
Chemical Class Thienothiazines Derivative
Action Class Carbonic Anhydrase Inhibitors (CAIs)
Habbit Forming
Manufacturer Sunways India Pvt Ltd
Manufacturer address 1002-1003, 10th Floor, Windfall, Sahar Plaza, J.B.Nagar, Andheri-Kurla Road, Andheri (East), Mumbai-400059. Maharashtra, India.

Brio Eye Drop
Brio Eye Drop is a medicine used to reduce increased pressure in the eye, in people with glaucoma or ocular hypertension(high pressure in the eye). If the pressure in your eye is too high it can damage your sight. Brio Eye Drop works by decreasing the amount of fluid inside the eye.
Basic Info
Description
Brio Eye Drop is a medicine used to reduce increased pressure in the eye, in people with glaucoma or ocular hypertension(high pressure in the eye). If the pressure in your eye is too high it can damage your sight. Brio Eye Drop works by decreasing the amount of fluid inside the eye.
Never use Brio Eye Drop if the seal is broken before you use it for the first time. Wash your hands before using it and shake the bottle well before each use. If you wear contact lenses, make sure you remove them before instilling them and wait for at least 15 minutes before putting them back. Do not stop using this medicine without asking your doctor. Otherwise, the pressure in your eye will not be controlled and this could damage your sight.
The most common side effects are blurred vision and a bitter taste in your mouth. Sometimes people experience more general effects such as shortness of breath, dizziness, tiredness, or heart palpitations. If your vision is blurred or you have other changes in sight for a time, do not drive until your vision is clear.
Do not use this medicine if you have severe kidney problems or are allergic to medicines called sulphonamides. Talk to your doctor before taking it if you have liver problems, dry eyes, or cornea problems. This medicine is not recommended for women who are pregnant or breastfeeding. Do not use other eye medications unless your doctor tells you to.
Uses
Glaucoma
Ocular hypertension
How To Use
This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Hold the dropper close to the eye without touching it. Gently squeeze the dropper and place the medicine inside the lower eyelid. Wipe off the extra liquid.
MOA
Brio Eye Drop is a carbonic anhydrase inhibitor. It works by decreasing the production of aqueous humour (fluid in the eye), thereby lowering the increased eye pressure.
What If
Q: What if you forget to take Brio Ophthalmic Suspension?
A: If you miss a dose of Brio Eye Drop, use it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Drug Tips
Brio Eye Drop helps lower high pressure in the eye and reduce the risk of vision loss.
For best results, put one drop 2-3 times daily in the affected eye(s).
Apply pressure on the corner of the eye (close to the nose) for about 1 minute, immediately after instilling the drop. This minimizes the risk of side effects.
Do not touch the tip of the dropper to any surface, or to your eye, to avoid contaminating the eye drops.
Remove contact lenses before using Brio Eye Drop, and wait at least 15 minutes before re-inserting them.
When applying multiple eye medications, wait for at least 5-15 minutes before delivering the next medication in the same eye to avoid dilution of the medicine.
Brio Eye Drop helps lower high pressure in the eye and reduce the risk of vision loss.
For best results, put one drop 2-3 times daily in the affected eye(s).
Apply pressure on the corner of the eye (close to the nose) for about 1 minute, immediately after instilling the drop. This minimizes the risk of side effects.
Do not touch the tip of the dropper to any surface, or to your eye, to avoid contaminating the eye drops.
Remove contact lenses before using Brio Eye Drop, and wait at least 15 minutes before re-inserting them.
When applying multiple eye medications, wait for at least 5-15 minutes before delivering the next medication in the same eye to avoid dilution of the medicine.
Faqs
Q. What is the right way to use Brio Eye Drop?
Always wash your hands before (and after) using Brio Eye Drop. This prevents you from passing the infection from one eye to the other. Remove the cap just before using your medicine and replace it as soon as you have finished. Avoid touching the nozzle of the bottle with your fingers. Tilt your head back and gently pull down your lower eyelid with a clean finger. Hold the bottle over the eye and allow a single drop to fall into the space between your lower lid and your eye. Close your eye and gently press your finger over the inside corner of your eye (over the eyelid) for about a minute. This helps prevent the drop from draining out of the eye. Repeat in your other eye if your doctor has told you to do this.
Q. How many times should I use Brio Eye Drop in a day?
Ideally, you should use the drops regularly, three times a day, or as prescribed by your doctor.
Q. Does Brio Eye Drop cause blurred vision?
When you instill the eye drops for the first time, it can make your eyes watery and may sometimes cause blurred vision. If this happens, it will quickly clear. Make sure you can see clearly again before you drive, or use tools or machines.
Q. I am experiencing headaches after the start of the treatment with Brio Eye Drop. Is this normal?
Although rare, headache is one of the side-effects of Brio Eye Drop. You may ask your doctor to recommend a suitable painkiller. If the headache continues, speak with your doctor.
Q. When should I seek a doctorโs advice?
You should contact your doctor immediately if you develop swelling in the eyelids, eye pain, dry eye(s), foreign body sensation in the eyes, headache, and discharge from the eyes. Also, inform your doctor if you had or have any scheduled eye surgery.
Q. Can I use Brio Eye Drop if I wear contact lenses?
If you usually wear contact lenses, do not wear them while you’re using Brio Eye Drop. You can re-insert the lens 15 minutes after using Brio Eye Drop. Contact your doctor if there is any eye irritation that persists.
Q. Can I use any other eye drop along with Brio Eye Drop?
Always consult your doctor before using any other eye drops along with Brio Eye Drop. It is advisable to give a gap of atleast 10-15 minutes between the two medications.
Q. In which conditions the use of Brio Eye Drop should be avoided?
Use of Brio Eye Drop should be avoided in patients who are allergic to it or any of its components. However, if you are not aware of any allergy or if you are using this medicine for the first time, consult your doctor.
Benifits
In Ocular hypertension
Brio Eye Drop belongs to a group of medicines called carbonic anhydrase inhibitors. It is used to reduce pressure in your eyes. If the pressure in your eye is too high, it can damage your sight. You should only use it in the affected eye and take it regularly as prescribed by your doctor. If you stop taking it, the pressure in your eye will not be controlled. This could lead to a loss of sight.
Side Effects
Blurred vision
Bitter taste
Safety Profile
Alcohol:
No interaction found/established
Pregnancy:CONSULT YOUR DOCTOR
Brio Eye Drop may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding:CONSULT YOUR DOCTOR
Brio Eye Drop is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving:UNSAFE
Brio Eye Drop may cause blurring of your vision for a short time just after its use. Do not drive until your vision is clear.
Kidney:
No interaction found/established
Liver:
No interaction found/established
Refferences
Brinzolamid. Camberley, Surrey: Novartis Pharmaceuticals UK Ltd.; 2000 [revised 22 Jun. 2018]. [Accessed 28 Jan. 2019] (online) Available from: View
Brinzolamide ophthalmic. Fort Worth, Texas: Alcon Laboratories Inc.; 2006. [Accessed 06 Feb. 2019] (online) Available from: View
Central Drugs Standard Control Organisation (CDSCO). [Accessed 03 Apr. 2019] (online) Available from: View

