Busulmax 2mg Tablet

Composition Busulfan (2mg)
Rx Prescription Required
Pack strip of 25 tablets
Storage Store below 30°C
Chemical Class Organosulfonic Acid Esters Derivative {Alkylating Agent
Action Class Alkylating agent
Habbit Forming No
Manufacturer GLS Pharma Ltd.
Manufacturer address R-4, Khirki Main Road, Malviya Nagar New Delhi- 110 017, (India)

Busulmax 2mg Tablet can be taken with or without food, but better to take it at the same time every day. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include decreased blood cells (red cells, white cells, and platelets), nausea, vomiting, and loss of appetite. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them.

Inform your doctor if you have a medical history, of bleeding disorders, heart or liver disease, radiation treatment or any infection. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using.  Inform your doctor immediately if you notice unusual bruising or bleeding or if you have dark, tarry, or bloody stools and sore throat. This medicine is known to reduce the number of blood cells in your blood thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with kidney, liver and heart function during treatment with this medicine. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Blood cancer (Chronic myeloid leukaemia)

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Busulmax 2mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

Busulmax 2mg Tablet is an anti-cancer medication. It works by damaging the genetic material (DNA and RNA) of the cancer cells. This stops their growth and multiplication.

If you miss a dose of Busulmax 2mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Take it at a same time every day, either with food or without food.

Do not skip any dose and complete the course as suggested by your doctor.

Use an effective method of birth control to avoid pregnancy while taking this medication.

Your doctor may get regular blood tests done to monitor the levels of blood cells in your blood.

Inform your doctor immediately if you notice unusual bruising or bleeding or if you have dark, tarry, or bloody stools and sore throat. 

Q. Does Busulmax 2mg Tablet cause hair loss?

Yes, Busulmax 2mg Tablet can cause hair loss.

Q. Is Busulmax 2mg Tablet a vesicant?

Yes. Busulmax 2mg Tablet is a vesicant (irritant).

In Blood cancer (Chronic myeloid leukaemia)

Blood cancer, also called leukemia, is a cancer of the blood-forming tissues, that decreases the body’s ability to fight infection. Busulmax 2mg Tablet kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Stomatitis (Inflammation of the mouth)

Insomnia (difficulty in sleeping)

Increased glucose level in blood

Headache

Fever

Diarrhea

Decreased potassium level in blood

Decreased magnesium level in blood

Loss of appetite

Vomiting

Nausea

Anxiety

Abdominal pain

Decreased blood cells (red cells, white cells, and platelets)

Alcohol:CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Busulmax 2mg Tablet. Please consult your doctor.

Pregnancy:CONSULT YOUR DOCTOR

Busulmax 2mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding:UNSAFE

Busulmax 2mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving:CONSULT YOUR DOCTOR

It is not known whether Busulmax 2mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

Kidney:SAFE IF PRESCRIBED

Busulmax 2mg Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Busulmax 2mg Tablet may not be needed in these patients. Please consult your doctor.

Liver:CONSULT YOUR DOCTOR

There is limited information available on the use of Busulmax 2mg Tablet in patients with liver disease. Please consult your doctor.

Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1685-86.

Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 171-72.

Drugs.com. Busulfan Pregnancy and Breastfeeding Warnings. view

Busulfan. Ireland: Aspen Pharma Trading Limited; 13 Jan. 1986 . view

Drugs and Lactation Database. Bethesda : National Library of Medicine ; 2006. Busulfan. . view