Cabaxan Injection

Composition Cabazitaxel (60mg/ml)
Rx Prescription Required
Pack vial of 1.5 ml Injection
Storage Store below 30°C
Chemical Class Taxanes Derivatives
Action Class Alkaloids-cytotoxic agents
Habbit Forming No
Manufacturer Intas Pharmaceuticals Ltd
Manufacturer address Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad – 380009. Gujarat. India.

Cabaxan Injection is given under the supervision of a healthcare professional and should not be self-administered. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. You should avoid drinking alcohol as it may increase your risk of liver damage.

The most common side effects of this medicine include Low red blood cell count, low platelet count, diarrhea, back pain, and hair loss. If they do not go away or get worse, tell your doctor. There may be ways of preventing or reducing these effects. It is very strong medicine and some people may develop serious side effects while taking it. This medicine may lower your ability to fight infections and lead to problems with your blood, liver or kidneys. Your doctor will advise you regular blood tests to check for these.

Before taking it, tell your doctor if you have liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. It may harm your baby. You and your partner should avoid becoming pregnant or fathering a child for several months after your treatment with it has stopped. Your doctor may perform several tests such as blood tests, and physical examinations both before and during treatment with this medicine.

Prostate cancer

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Cabaxan Injection is an anti-cancer medication. It works by damaging the genetic material (DNA) of the cancer cells and stops their growth and multiplication.

If you miss a dose of Cabaxan Injection, please consult your doctor.

Cabaxan Injection is given as an infusion into a vein (IV infusion) under the supervision of a doctor only.

Do not skip any dose and complete the course as suggested by your doctor.

Use an effective method of birth control to avoid pregnancy while taking this medication.

You may need to have blood tests to monitor your blood cells, platelets count, liver function and kidney function during treatment.

Inform your doctor immediately if you notice unusual bruising or bleeding or if you have dark, tarry, or bloody stools and sore throat.

Q. Is Cabaxan Injection a vesicant or chemotherapeutic drug?

Cabaxan Injection is a chemotherapeutic drug (drug used for the management of cancer). It is, however, not a vesicant (drug which causes severe blisters on the skin).

In Prostate cancer

Prostate gland is a small walnut-sized gland that produces a fluid called seminal fluid that nourishes and transports sperms in males. The most common symptom of prostate cancer is difficulty with urination, but sometimes there are no symptoms at all. Cabaxan Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells in men. This also relieves difficulty in passing urine and makes it easier for you to urinate.

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Nausea

Decreased white blood cell count (neutrophils)

Breathing problems

Taste change

Cough

Constipation

Blood in urine

Stomatitis (Inflammation of the mouth)

Diarrhea

Anemia (low number of red blood cells)

Loss of appetite

Abdominal pain

Hair loss

Low blood platelets

Weakness

Back pain

Vomiting

Alcohol:UNSAFE

It is unsafe to consume alcohol with Cabaxan Injection.

Pregnancy:CONSULT YOUR DOCTOR

Cabaxan Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding:CONSULT YOUR DOCTOR

Cabaxan Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving:UNSAFE

Cabaxan Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney:SAFE IF PRESCRIBED

Cabaxan Injection is safe to use in patients with kidney disease. No dose adjustment of Cabaxan Injection is recommended.Caution is advised in patients with severe kidney disease and end stage kidney disease as the information available is limited for use of this medicine in these patients.

Liver:CAUTION

Cabaxan Injection should be used with caution in patients with liver disease. Dose adjustment of Cabaxan Injection may be needed. Please consult your doctor.Use of Cabaxan Injection is not recommended in patients with severe liver disease.

Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 176-78.

Cabazitaxel. Oxford, Oxfordshire: Genzyme Therapeutics; 2011 . view

Cabazitaxel. Bridgewater, New Jersey: Sanofi-aventis; 2010. view

Central Drugs Standard Control Organisation . view