Composition Alemtuzumab (30mg)
Rx Prescription Required
Pack vial of 1 Injection
Storage Store below 30ยฐC
Chemical Class Monoclonal antibody (mAb)
Action Class CD52 Inhibitors
Habbit Forming No
Manufacturer Zydus Cadila
Manufacturer address Zydus Tower, Satellite Cross Roads,Ahmedabad โ 380015 Gujarat, India.

Campath 30mg Injection
Campath 30mg Injection is used in the treatment of blood cancer (chronic lymphocytic leukemia) and multiple sclerosis (MS). It marks the cancer cells for destruction by the body’s immune system. It also modulates the immune system to limit its attacks on the nervous system.
Basic Info
Description
Campath 30mg Injection is given under the supervision of a doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Rash, headache, and insomnia are some common side effects of this medicine. This medicine may reduce the number of blood cells (white blood cells) in your blood, thereby, increasing the susceptibility to infections or bleeding. Thus, inform your doctor immediately if you develop fever, chills, cough, mouth sores, or trouble breathing, and unusual bruising or bleeding, or blood in the urine. You will be checked regularly after giving the medication as it may cause fatal reactions such as chest pain, breathlessness, slow or irregular heartbeat.
Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Uses
Blood cancer (Chronic lymphocytic leukemia)
Multiple sclerosis (MS)
How To Use
Your doctor or nurse will give you this medicine. Kindly do not self administer.
MOA
Campath 30mg Injection is a monoclonal antibody. It flags the cancer cells for destruction by the body’s immune system. It also modulates the immune system to limit its attacks on the nervous system.
What If
If you miss a dose of Campath 30mg Injection, please consult your doctor.
Drug Tips
Campath 30mg Injection is given as an injection into the veins under the supervision of a doctor.
Faqs
Q. How will you know that Campath 30mg Injection is working?
Keep taking this medicine exactly as directed until your doctor tells you to stop. Regular scans will reveal whether your tumor is responding to the treatment. Your doctor will determine when those scans should be scheduled.
Q. What precautions should I take to reduce the chances of getting infected during treatment with Campath 30mg Injection?
Since Campath 30mg Injection lowers the number of white blood cells and platelets in your blood, it puts you at a risk of getting an infection or bleeding. In order to prevent, avoid people who have infections. Check with your doctor immediately if you think you may be getting an infection, or if you get a fever, chills, cough; be careful not to cut yourself when you are using sharp objects such as a razor or nail cutters; and use a toothbrush with soft bristles to prevent bleeding from gums.
Q. How to get relief from feelings of nausea during the treatment?
Eat smaller, more frequent meals to reduce the feeling of nausea. Avoid food that is salty, spicy, fried, or fatty. Sucking on lozenges and chewing gums may also help.Your doctor might prescribe you some anti-nausea medications to get immediate relief.
Q. I have noticed some changes in my skin, and hair after taking Campath 30mg Injection. What should I do?
Use a moisturizer to get relief from rashes, dry and itchy skin. While taking this medicine, the hair on your head may become brittle. You may also experience patchy hair loss or thinning. This tends to resolve once treatment is stopped.
Q. Are there any precaution for tingling sensation and numbness in my arms and legs?
This medicine causes tingling, numbness, pain, or burning sensation in your arms or legs. Be careful when moving around, as the numbness may make it harder to walk, feel your hands or feet, or increase your risk of falls. Talk to your doctor if you feel these symptoms. You may need to change your dose or schedule.
Q. What are some of the tests conducted before and during the treatment with Campath 30mg Injection?
Your doctor will prescribe blood tests to check your levels of blood cells and how well your liver and kidneys are working.
Q. Can Campath 30mg Injection be taken during pregnancy?
This treatment may harm a baby developing in the womb. It is important not to become pregnant or father a child while you are having treatment and for at least 6 months afterward. Talk to your doctor about effective contraception before starting the treatment.
Q. Is Campath 30mg Injection safe during breastfeeding?
Do not breastfeed while taking this medicine and for 4 months after the last dose. This is because Campath 30mg Injection might pass into breast milk and could therefore harm your baby.
Q. Can I take vaccination while on treatment with Campath 30mg Injection?
It is advisable not to receive any kind of immunization with live vaccine while taking this medicine and for up to 12 months afterward. The length of time depends on the treatment you are having. Ask your doctor how long you should avoid live vaccinations.
Q. When should I call my doctor right away?
Get medical help right away if you have swelling in your mouth or throat, trouble breathing, severe weakness, fast, slow, or irregular heartbeat, chest pain, and severe rash.
Benifits
In Blood cancer (Chronic lymphocytic leukemia)
Blood cancer, also called leukemia, is a cancer of the blood-forming tissues, that decreases the body’s ability to fight infection. Campath 30mg Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is an effective medicine but you should discuss the side effects and benefits of this medicine with your doctor. Let your doctor know if any of the side effects bothers you.
In Multiple sclerosis (MS)
Multiple sclerosis (MS) is a disease of the brain and spinal cord in which a personโs own immune system attacks the protective sheath (called myelin) of the nerves. This leads to symptoms such as vision loss, pain, fatigue and improper coordination. Campath 30mg Injection helps to suppress the bodyโs immune system, thereby reducing the progression of the disease. It reduces the inflammation of the damaged nerves, prevents further damage and stabilises your immune system. It improves muscle strength and helps the patients to walk better. This makes the patients more confident and enhances their quality of life.show moreshow less
Side Effects
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if youโre worried about them
Decreased white blood cell count (lymphocytes)
Hives
Flushing (sense of warmth in the face, ears, neck and trunk)
Itching
Fever
Fatigue
Decreased white blood cell count
Upper respiratory tract infection
Nausea
Insomnia (difficulty in sleeping)
Headache
Rash
Safety Profile
Alcohol:CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Campath 30mg Injection. Please consult your doctor.
Pregnancy:CONSULT YOUR DOCTOR
Campath 30mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding:CONSULT YOUR DOCTOR
Campath 30mg Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving:UNSAFE
Campath 30mg Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney:CONSULT YOUR DOCTOR
There is limited information available on the use of Campath 30mg Injection in patients with kidney disease. Please consult your doctor.
Liver:CONSULT YOUR DOCTOR
There is limited information available on the use of Campath 30mg Injection in patients with liver disease. Please consult your doctor.
Refferences
Krensky AM, Bennett WM, Vincenti F. Immunosuppressants, Tolerogens, and Immunostimulants. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilmanโs: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1018.
Lake DF, Briggs AD, Akporiaye ET. Immunopharmacology. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 977.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 35.
Alemtuzumab. Oxford, Oxfordshire: Genzyme Therapeutics; 2013 . view
Alemtuzumab. Kendall Street Cambridge, MA: Genzyme Corporation; 2001. view
Drugs and Lactation Database. Bethesda : National Library of Medicine ; 2006. Alemtuzumab. . view

