Composition Carboplatin (10mg/ml)
Rx Prescription Required
Pack vial of 15 ml Injection
Storage Store below 30°C
Chemical Class Platinum Analogs
Action Class Platinum-Based Alkylating Agents
Habbit Forming
Manufacturer Alkem Laboratories Ltd
Manufacturer address Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai – 400 013.
Carbokem Nova 150 Injection
Carbokem Nova 150 Injection is used in the treatment of ovarian cancer and small cell lung cancer. It shows its working by stopping or slowing down the growth of cancer cells.
Basic Info
Description
Carbokem Nova 150 Injection is used in the treatment of ovarian cancer and small cell lung cancer. It shows its working by stopping or slowing down the growth of cancer cells.
Carbokem Nova 150 Injection is given as an injection into veins under the supervision of a doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Nausea, vomiting, fatigue, and increased liver enzyme are some common side effects of this medicine. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections or bleeding. Inform your doctor if you notice fever, sore throat, chills, unusual bleeding or bruising, and dark urine. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels.
You must inform your doctor if you experience allergic reactions with injection such as skin rash, itching, and trouble breathing. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Uses
Ovarian cancer
Small cell lung cancer
How To Use
Your doctor or nurse will give you this medicine. Kindly do not self administer.
MOA
Carbokem Nova 150 Injection is an anti-cancer medication. It works by damaging the genetic material (DNA and RNA) of the cancer cells which stops their growth and multiplication.
What If
Q: What if you forget to take Carbokem Nova Injection?
A: If you miss a dose of Carbokem Nova 150 Injection, please consult your doctor.
Drug Tips
It is given as an injection into the veins under the supervision of a doctor.
Faqs
Q. Is Carbokem Nova 150 Injection cell cycle specific?
No, Carbokem Nova 150 Injection is not a cell cycle specific anticancer medication
Q. Is Carbokem Nova 150 Injection FDA approved?
Yes Carbokem Nova 150 Injection is an FDA approved drug
Q. Is it a platinum based drug?
Yes carboplatin is a platinum based drug and is effectively used in combination with other drug
Q. Does Carbokem Nova 150 Injection cause neuropathy/ hearing loss/ hair loss/ weight gain/ constipation/ leukemia?
Yes Carbokem Nova 150 Injection is known to cause side effects like neuropathy, hearing loss, hair loss, weight gain, and constipation. Please inform your doctor about any side-effect that you may observe on taking this drug. Infertility while on therapy may be caused as a side effect of this drug but it may be reverse after stopping the therapy. Yes Carbokem Nova 150 Injection may cause leukemia if it is used for a long duration.
Q. Is Carbokem Nova 150 Injection a generic?
Yes, Carbokem Nova 150 Injection is a generic platinum-based compound
Q. Is Carbokem Nova 150 Injection vesicant/cardio-toxic/ anthracycline?
No Carbokem Nova 150 Injection is not cardio-toxic/ anthracycline/vesicant
Q. Is Carbokem Nova 150 Injection used for breast cancer?
It is used to treat advanced stage breast cancer
Q. Is Carbokem Nova 150 Injection available in pill form?
No Carbokem Nova 150 Injection is not available in pill form
Benifits
In Ovarian cancer
Ovarian cancer is a cancer that begins in the female organs that produce eggs (ovaries). This type of cancer is usually detected very late and can be fatal too. It usually spreads to the pelvis and stomach. Carbokem Nova 150 Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is an effective medicine but has some side effects that may be bothersome. So, you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.
Side Effects
Nausea
Vomiting
Anemia (low number of red blood cells)
Fatigue
Low blood platelets
Increased liver enzymes
Decreased white blood cell count (neutrophils)
Stomatitis (Inflammation of the mouth)
Peripheral neuropathy (tingling and numbness of feet and hand)
Diarrhea
Safety Profile
Alcohol:CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Carbokem Nova 150 Injection. Please consult your doctor.
Pregnancy:CONSULT YOUR DOCTOR
Carbokem Nova 150 Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding:UNSAFE
Carbokem Nova 150 Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving:UNSAFE
Carbokem Nova 150 Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney:CAUTION
Carbokem Nova 150 Injection should be used with caution in patients with kidney disease. Dose adjustment of Carbokem Nova 150 Injection may be needed. Please consult your doctor.Use of Carbokem Nova 150 Injection is not recommended in patients with severe kidney disease. Regular monitoring of kidney function tests may be advised while you are taking this medicine.
Liver:SAFE IF PRESCRIBED
Carbokem Nova 150 Injection is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Carbokem Nova 150 Injection may not be needed in these patients. Please consult your doctor.
Refferences
Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1689.
Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 944.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 205-207.
Carboplatin. Maidenhead: Hospira UK Limited; 20 Jul. 2005 [revised Nov. 2018]. [Accessed 26 Mar. 2019] (online) Available from: View
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