Celofos 2gm Injection

Celofos 2gm Injection is usually given as a slow infusion (drip) into a vein (intravenously) over several hours. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. It is advised that you drink extra fluids so that you pass more urine. This will help prevent bladder and kidney problems and keep your kidneys working well.

The most common side effects of this medicine include nausea, vomiting, anemia (low number of red blood cells), hair loss, decreased white blood cells count.  If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. It is very strong medicine and some people may develop serious side effects while taking it. This medicine may lower your ability to fight infections and lead to problems with your blood, liver or kidneys.

Before taking it, tell your doctor if you have liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. It may harm your baby. You and your partner should avoid becoming pregnant or fathering a child for several months after your treatment with it has stopped.

Pancreatic cancer
Ovarian cancer
Breast cancer
Non-small cell lung cancer
Testicular cancer
Blood cancer

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Celofos 2gm Injection is an anti-cancer medication. It works by damaging the genetic material (DNA and RNA) of the cancer cells. This stops their growth and multiplication.

If you miss a dose of Celofos 2gm Injection, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Celofos 2gm Injection is used in combination with other chemotherapy medicines, radiotherapy and surgery to treat cancer of blood, breast, lung, ovaries, pancreas, testes, and lymph nodes.

It is usually given as a slow infusion (drip) into a vein (intravenously) over several hours.

Drink plenty of fluids while taking this  medication to minimise damage to your bladder and kidneys.

It may cause dizziness and sleepiness. Don’t drive or do anything that requires mental focus until you know how it affects you.

Use effective measures to avoid pregnancy during treatment with this medicine and for at least 6 months after your last dose as it can be harmful to an unborn baby. 

Your doctor may have your blood tested regularly to monitor your kidney, liver function and levels of blood cells in your blood.

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In Pancreatic cancer

Pancreas are very essential for digestion of whatever you eat and also for metabolism of blood sugar levels as they produce the body’s natural insulin. This medicine will help to control pancreatic cancer, and will relieve the symptoms such as, lack of appetite or unexplained weight loss. Celofos 2gm Injection helps to stop the action of those chemicals that aid in pancreatic cancer growth and spread. It will help you live a longer and healthier life.

In Ovarian cancer

Ovarian cancer is a cancer that begins in the female organs that produce eggs (ovaries). This type of cancer is usually detected very late and can be fatal too. It usually spreads to the pelvis and stomach. Celofos 2gm Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is an effective medicine but has some side effects that may be bothersome. So, you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

In Breast cancer

Celofos 2gm Injection helps to treat breast cancer and it may be used alone or in combination with other medicines or treatment modalities like chemotherapy, to treat cancer in various parts of the body. It relieves the symptoms of breast cancer such as breast lumps, bloody discharge from nipples or changes in the shape or texture of the breast. Celofos 2gm Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. Discuss with your doctor if any of the side effects bother you.

In Non-small cell lung cancer

Non-small cell lung cancer is one of the major kinds of lung cancer and it affects both smokers as well as non-smokers. Celofos 2gm Injection helps treat non-small cell lung cancer and may be given alone or in combination with other medicines. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

In Testicular cancer

Testicular cancer is the cancer in the male organs called testicles, that make male hormones and sperm. The testicles are located inside a loose bag of skin (scrotum) underneath the penis. Celofos 2gm Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells in men. It is given as an injection by a doctor or nurse and should not be self-administered.

In Blood cancer

Blood cancer, also called leukemia, is a cancer of the blood-forming tissues, that decreases the body’s ability to fight infection. Celofos 2gm Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.show moreshow less

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

CNS toxicity

Blood in urine

Infection

Decreased white blood cell count

Hair loss

Anemia (low number of red blood cells)

Vomiting

Nausea

Alcohol:UNSAFE

It is unsafe to consume alcohol with Celofos 2gm Injection.

Pregnancy:CONSULT YOUR DOCTOR

Celofos 2gm Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding:UNSAFE

Celofos 2gm Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving:UNSAFE

Celofos 2gm Injection may cause side effects which could affect your ability to drive.

Kidney:CAUTION

Celofos 2gm Injection should be used with caution in patients with kidney disease. Dose adjustment of Celofos 2gm Injection may be needed. Please consult your doctor.

Liver:CAUTION

Celofos 2gm Injection should be used with caution in patients with liver disease. Dose adjustment of Celofos 2gm Injection may be needed. Please consult your doctor.

Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1683-84.

Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 688-90.

Ifosfamide. Deerfield, Illinois: Baxter Healthcare Corporation; 1988 . view

Drugs.com. Ifosfamide Pregnancy and Breastfeeding Warnings. view

Ifosfamide. Deerfield, Illinois: Baxter Healthcare Corporation. view