Cetrovian 0.25mg Injection

Composition Cetrorelix (0.25mg)
Rx Prescription Required
Pack vial of 1 Injection
Storage Store in a refrigerator (2 – 8°C). Do not freeze.
Chemical Class Polypeptides
Action Class Gonadotropin-releasing hormone (GnRH) Antagonists
Habbit Forming
Manufacturer Nivian Pharma LLP
Manufacturer address 3rd Floor, Prabhu Vijay, V M Road, Vile Parle West Mumbai Mumbai City MH 400056 IN

Cetrovian 0.25mg Injection is an anti-gonadotropin-releasing hormone medicine. It is used in the treatment of infertility in females. It restricts eggs to release directly and prevents premature ovulation.

Cetrovian 0.25mg Injection is injecting directly into the skin under the supervision of a doctor. Do not self administer the injection. Your doctor or nurse may help you to know the best way to inject the medicine at home. The dose and how often you take it depends on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. You should take this medicine for as long as it is prescribed for you.

The most common side effects of this medicine include injection site reaction (redness, itching, and irritation), nausea and vomiting.  To overcome irritation at the injection site, use a different part of belly every day to inject the medicine. Some side effects may mean you should inform your doctor immediately include dizziness, faint, abdominal pain, and vomiting.

Before taking this medicine, tell your doctor if you have ever had liver or kidney disease or if you are breastfeeding to a baby. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works.

Female infertility

Prostate cancer

Your doctor or nurse will give you this medicine. Kindly do not self administer.

In females undergoing treatment for infertility, sometimes premature ovulation can lead to the release of eggs which are not ready for fertilisation. Cetrovian 0.25mg Injection blocks the action of a natural hormone and prevents premature release of the eggs from the ovary.

Q: What if you forget to take Cetrovian Injection?
A: If you miss a dose of Cetrovian 0.25mg Injection, please consult your doctor.n

Cetrovian 0.25mg Injection helps prevent premature ovulation in women undergoing assisted reproduction treatments such as IVF.

It is given as an injection under the skin (subcutaneously), preferably of the upper leg.

Inform your doctor immediately if you get very dizzy, faint, vomit, or have diarrhea while using this medicine. These could be symptoms of ovarian hyperstimulation syndrome (OHSS).

Do not use this medicine if you are already pregnant or breastfeeding.

Q. What is Cetrovian 0.25mg Injection and for what it is used for?

Cetrovian 0.25mg Injection is an injectable preparation, which contains the active substance Ganirelix. It is used in women undergoing certain fertility treatments. It acts by blocking the release of luteinizing hormone (LH) thus preventing eggs from being released too early and gives the eggs time to grow properly. It is usually used in combination with other medicines.

Q. How and in what dose can it be used?

It is given as an injection, only at the hospital or clinic by the medical healthcare professional. The patient may be monitored regularly for the follicular development. The treatment duration depends on the ovarian response of the patient.

Q. What may be the possible side effects associated with it?

The most common side effect is local site reaction (redness of skin with or without swelling). You may also feel a headache or nausea. However, these effects are temporary, if these persist consult with your doctor. In addition, conditions like ovarian hyperstimulation syndrome (OHSS), and multiple births or birth defect, may also be associated with the use of this medicine.

Nausea

Ovarian hyperstimulation syndrome

Injection site reactions (pain, swelling, redness)

Itching

Irritation

Vomiting

Lower abdominal pain

Alcohol:CAUTION

Caution is advised when consuming alcohol with Cetrovian 0.25mg Injection. Please consult your doctor.

Pregnancy:UNSAFE

Cetrovian 0.25mg Injection is highly unsafe to use during pregnancy. Seek your doctor’s advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.

Breast feeding:UNSAFE

Cetrovian 0.25mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving:SAFE

Cetrovian 0.25mg Injection does not usually affect your ability to drive.

Kidney:CAUTION

Cetrovian 0.25mg Injection should be used with caution in patients with kidney disease. Dose adjustment of Cetrovian 0.25mg Injection may be needed. Please consult your doctor.However, the use of Cetrovian 0.25mg Injection is not recommended in patients with severe kidney disease.

Liver:CAUTION

Cetrovian 0.25mg Injection should be used with caution in patients with liver disease. Dose adjustment of Cetrovian 0.25mg Injection may be needed. Please consult your doctor.

Masters SB. Hypothalmic & Pituitary Hormones. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 655.
FDA. Ganirelix Acetate Injection. [Accessed 29 Jan. 2019] (online) Available from: View
Cetrorelix acetate. Rockland, Massachusetts: EMD Serono, Inc.; 2008. [Accessed 08 Feb. 2019] (online) Available from: View