Combe Five Suspension for Injection

Composition Diphtheria Toxoid (30IU) + Tetanus Toxoid (60IU) + Pertussis Toxoid (4IU) + Hepatitis B Vaccine (rDNA) (12.5mcg) + Haemophilus Influenzae Type B Capsular Polysaccharide (11mcg)
Rx Prescription Required
Pack vial of 0.5 ml Suspension for Injection
Storage
Chemical Class
Action Class
Habbit Forming No
Manufacturer Biological E Ltd
Manufacturer address Biological E. Limited, Road No. 35,Jubilee Hills, Hyderabad, Telangana -500033

Combe Five Suspension for Injection is to be administered by a healthcare professional. It may cause redness, pain, and swelling at the site of injection. However, this is temporary and usually resolves on its own. Do not skip any doses and follow your doctor’s instructions carefully to get maximum benefit.

Combe Five Suspension for Injection is generally safe to use with minimal side effects. However, it may cause a few side effects such as fever, vomiting, headache, etc. Please consult your doctor if these do not subside or bother you. Your doctor will suggest ways to cope up with the side effects.

Before taking it, inform your doctor if you are suffering from any liver or kidney problems. Pregnant and breastfeeding mothers should consult their doctor before taking it.

Haemophilus influenzae Type b disease

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Combe Five Suspension for Injection is a vaccine.It helps develop immunity by initiating a mild infection. This type of infection does not cause illness, but it does stimulate the body’s immune system to produce antibodies to protect against any future infections.

Do not panic. If you miss a schedule of Combe Five Suspension for Injection, do consult your child’s doctor and get your child vaccinated as soon as possible.

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Q. Is diphtheria toxin an endotoxin?

No, diphtheria toxin is an exotoxin and not an endotoxin

Q. Is diphtheria toxin a protein?

Yes, diphtheria toxin is an extracellular protein of the bacteria Corynebacterium diphtheriae.

Q. What type of immunity does Tetanus Toxoid provide?

Tetanus Toxoid provides artificial active immunity. This type of immunity is generated when a dead or weakened version of the disease enters the body, causing an immune response which includes the production of antibodies. Vaccination with Tetanus Toxoid helps to prevent the deadly disease, tetanus.

Q. What is a booster dose or booster vaccine or booster shot?

A booster dose or booster vaccine or booster shot is an additional dose of a vaccine that may have to be administered periodically (usually once every few years) after completing the initial or primary vaccination against certain diseases. This helps to ‘boost’ your immunity against such diseases so that you are adequately protected against them.

Q. Is there a cure for tetanus?

There is no cure for tetanus once a person develops symptoms, just supportive treatment and management of complications can be done in a hospital setup. The best way to treat tetanus is its prevention through vaccination or immunization.

Q. How long does it take to show signs of tetanus after being exposed?

After being exposed, the incubation period varies from 3 to 21 days, with an average of eight days. The further the injury site is from the central nervous system, the longer the incubation period. The shorter the incubation period, the higher the risk of death.

Q. What are the symptoms of tetanus? How does Tetanus Toxoid work?

Tetanus symptoms involve tightening of muscles of the body and causing a locked jaw, thus making it impossible to breathe, open the mouth to eat or swallow. Tetanus Toxoid works by helping the body produce substances that resist infection from bacteria causing tetanus.

Q. Who should get Tetanus Toxoid?

Tetanus Toxoid should be given to everyone, even to children as early as 2 months of age. Booster doses are recommended for everyone almost every 10 years. Consult your doctor if you have any doubts regarding the vaccination.

Q. What if I miss a dose of Tetanus Toxoid?

If a scheduled vaccination booster dose of Tetanus Toxoid is missed, talk to your doctor and arrange another visit as soon as possible.

Q. Is Tetanus Toxoid a safe vaccine?

Various studies and trials have shown that Tetanus Toxoid is a safe and effective vaccine. Hence, it has been approved for use and recommended by various medical organizations and doctors all around the world. By preventing life-threatening diseases like tetanus, it has proven to be of immense benefit. Tetanus Toxoid is also well tolerated. Any side effects that may be seen with this vaccine are usually minor and tend to resolve quickly.

Q. Who all should get vaccinated with Hepatitis B Vaccine (rDNA)?

Everyone should get vaccinated with Hepatitis B Vaccine (rDNA). All infants, beginning at birth, all children aged up to 19 years who have not been vaccinated previously and persons with chronic liver disease, other than hepatitis B (e.g. cirrhosis, fatty liver disease, etc.) or those with HIV infection must also get this vaccination. Additionally, suspected sexual partners of hepatitis B-positive persons or victims of sexual assault (rape) or abuse are also advised to get vaccinated with Hepatitis B Vaccine (rDNA) to be protected against Hepatitis B infection.

Q. Is hepatitis B infection curable?

No. In most cases, the symptoms of hepatitis B infection is resolved within 4-8 weeks but person remain infected for lifetime. In some cases, however, symptoms may persist for a longer time (chronic infection)

Q. Is hepatitis B infection fatal or life-threatening?

Yes. Hepatitis B infection symptoms, if present for a longer time, may cause chronic infection, liver cirrhosis or liver cancer and can also be life threatening.

Q. Is hepatitis B infection contagious?

Yes. Hepatitis B virus infection is contagious.

Q. Does it spread through saliva or sharing of food?

Yes. Hepatitis spreads through contact with the body fluids including saliva, blood, semen etc. of the infected person.

Q. Does hepatitis B vaccine cause fever?

Mild fever may occur after hepatitis B vaccine administration. Contact your doctor if your fever worsens or does not go away.

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Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Vomiting

Unusual crying

Erythema (skin redness)

Restlessness

Loss of appetite

Injection site swelling

Injection site pain

Fever

Diarrhea

Allergic reaction

Alcohol:

There is no data available. Please consult doctor before consuming the drug.

Pregnancy:

There is no data available. Please consult doctor before consuming the drug.

Breast feeding:

There is no data available. Please consult doctor before consuming the drug.

Driving:

There is no data available. Please consult doctor before consuming the drug.

Kidney:SAFE IF PRESCRIBED

Combe Five Suspension for Injection is safe to use in patients with kidney disease. No dose adjustment of Combe Five Suspension for Injection is recommended.

Liver:SAFE IF PRESCRIBED

Combe Five Suspension for Injection is safe to use in patients with liver disease. No dose adjustment of Combe Five Suspension for Injection is recommended.

Diphtheria, Tetanus, Pertussis , Hepatitis Band Haemophilus Type b Conjugate Vaccine. Solan, Himachal Pradesh: Panacea Biotec Ltd.; 2009. view

Diphtheria, Tetanus, Pertussis , Hepatitis Band Haemophilus Type b Conjugate VaccineI.P. Genome Valley, Hyderabad: Bharat Biotech. view

Ministry of Health $ Family Welfare, Government of India. Frequently Asked Questions on Immunization. 2017. view

MSF Medical Guidelines. Diphtheria, Tetanus, Pertussis, Hepatitis B, Hib Vaccine. view

Caring for Kids. 5-in-1 or 6-in-1 vaccine. . view