Composition Carmustine (100mg)
Rx Prescription Required
Pack vial of 1 Injection
Storage Store below 30°C
Chemical Class Nitrogen Mustard Compounds
Action Class Alkylating agent
Habbit Forming No
Manufacturer Emcure Pharmaceuticals Ltd
Manufacturer address 255/2, Hinjawadi, Pune – 411057, India

Consium 100mg Injection
Consium 100mg Injection is used to treat cancer of lymphatic system, brain and certain types of cancers of bone marrow. It may also be used to treat other types of cancer. It can be used alone, or together with certain other medicines as part of combination chemotherapy.
Basic Info
Description
Consium 100mg Injection is generally administered by a doctor or a nurse. You should not self-administer this medicine at home. This dose and duration of the treatment will depend on what you are being treated and the severity of your condition. You should get the injection regularly for as long as the doctor has prescribed.
The most common side effects of this medicine include nausea, vomiting, constipation, depression, sleepiness, speech disorder, rash, hair loss, headache, weakness, fever, and pain. Other than this, some patients might notice thrombophlebitis, paralysis of one side of the body, convulsion, confusion, and brain swelling. It is very strong medicine and some people may develop serious side effects while taking it. This medicine may lower your ability to fight infections and lead to problems with your blood, lungs, liver, or kidneys. Your doctor will advise you regular blood tests to check for these.
Before taking it, tell your doctor if you have liver, lungs, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. It may harm your baby. You and your partner should avoid becoming pregnant or fathering a child for several months after your treatment with it has stopped.
Uses
Brain tumor
How To Use
Your doctor or nurse will give you this medicine. Kindly do not self administer.
MOA
Consium 100mg Injection is an anti-cancer medication. It works by damaging the genetic material (DNA and RNA) of the cancer cells. This stops their growth and multiplication.
What If
If you miss a dose of Consium 100mg Injection, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Drug Tips
Consium 100mg Injection is given as an injection into the veins under the supervision of a doctor.
Faqs
Q. Is Consium 100mg Injection safe?
Consium 100mg Injection is safe if taken at prescribed dose and duration as advised by your doctor.
Q. Is Consium 100mg Injection a vesicant?
Consium 100mg Injection is classified under irritants amongst chemotherapy drugs. However when administered at high doses it can act as vesicant.
Q. Does Consium 100mg Injection inhibit DNA replication?
Yes, Consium 100mg Injection works by preventing DNA replication.
Benifits
In Brain tumor
Brain tumor is an abnormal mass or collection of cells that may be cancerous (malignant) or non-cancerous (benign). Consium 100mg Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.
Side Effects
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Pain
Hemiplegia (paralysis of one side of the body)
Sleepiness
Hemiplegia (paralysis of one side of the body)
Thrombophlebitis
Brain swelling
Speech disorder
Depression
Convulsion
Hair loss
Infection
Confusion
Weakness
Constipation
Rash
Fever
Headache
Vomiting
Nausea
Safety Profile
Alcohol:CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Consium 100mg Injection. Please consult your doctor.
Pregnancy:CONSULT YOUR DOCTOR
Consium 100mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding:UNSAFE
Consium 100mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving:UNSAFE
Consium 100mg Injection may cause side effects which could affect your ability to drive.
Kidney:CONSULT YOUR DOCTOR
There is limited information available on the use of Consium 100mg Injection in patients with kidney disease. Please consult your doctor.However, the use of Consium 100mg Injection is not recommended in patients with severe kidney disease.
Liver:CONSULT YOUR DOCTOR
There is limited information available on the use of Consium 100mg Injection in patients with liver disease. Please consult your doctor.
Refferences
Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1686.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 211-13.
Carmustine. India: Emcure Pharmaceuticals; 2013. view
Carmustine. Princeton, New Jersey: Bristol-Myers Squibb; 2011. view
Central Drugs Standard Control Organisation . view
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