Composition Darbepoetin alfa (200mcg)
Rx Prescription Required
Pack prefilled syringe of 1 Injection
Storage Store in a refrigerator (2 – 8ยฐC). Do not freeze.
Chemical Class Amino Acids, Peptides Analogues
Action Class Erythropoiesis-Stimulating Agents (ESAs)
Habbit Forming
Manufacturer Dr Reddy’s Laboratories Ltd
Manufacturer address Dr. Reddy’s Laboratories Ltd., Village Malpur, P.O.Bhud, Baddi, Dist. Solan, H.P.

Cresp Onco 200 Injection
Cresp Onco 200 Injection is used in the treatment of anemia that may have occurred due to chronic kidney disease or chemotherapy. It works by stimulating the bone marrow to produce more red blood cells.
Basic Info
Description
Cresp Onco 200 Injection is used in the treatment of anemia that may have occurred due to chronic kidney disease or chemotherapy. It works by stimulating the bone marrow to produce more red blood cells.
Cresp Onco 200 Injection is a medicine that needs to be used with utmost care because it can lead to serious side effects. It is important that you seek treatment from a doctor who is experienced in providing this medical therapy. You should follow all the directions of the doctor strictly. It is given under the supervision of a healthcare professional.
Common side effects include abdominal pain, high blood pressure, rash, injection site pain, breathlessness, cough, and peripheral edema. Inform your doctor if there are symptoms of very high blood pressure, such as severe headache, problems with your eyesight, nausea, vomiting, or fits (seizures).
Your doctor may get your blood tests done regularly to monitor the levels of salts (electrolytes such as potassium), hemoglobin, and blood cells in your blood. You should stop taking it and consult with a doctor if you develop shortness of breath or a skin rash.
Before taking Cresp Onco 200 Injection, tell your doctor if you have heart disease, high blood pressure, or have had a seizure or stroke. If you are pregnant or breastfeeding, or plan to become pregnant, consult your doctor to make sure it is safe for you.
Uses
Treatment of Anemia due to cancer chemotherapy
Treatment of Anemia due to chronic kidney disease
How To Use
Your doctor or nurse will give you this medicine. Kindly do not self administer.
MOA
Cresp Onco 200 Injection is an erythropoiesis-stimulating agent (ESA). It works by stimulating the bone marrow (soft tissue inside the bones which produces red blood cells) to produce more red blood cells.
What If
Q: What if you forget to take Cresp Onco Injection?
A: If you miss a dose of Cresp Onco 200 Injection, consult your doctor.
Drug Tips
Cresp Onco 200 Injection helps in the treatment of anemia that may have occurred due to chronic kidney disease or cancer chemotherapy.
It is given as a single injection under your skin; additionally, it can be given intravenously.
Your doctor may get your blood tests done regularly to monitor the levels of hemoglobin in your blood.
Stop taking Cresp Onco 200 Injection and inform your doctor if you develop shortness of breath or a skin rash.
Faqs
Q. How long does it take for Cresp Onco 200 Injection to start working?
You will be able to notice an increase in the count of red blood cells (hemoglobin levels) in 2-6 weeks of starting Cresp Onco 200 Injection. If you have any other concerns, consult your doctor.
Q. Is Cresp Onco 200 Injection safe to use?
Cresp Onco 200 Injection is a medicine that needs to be used with utmost care because it can lead to serious side effects and even death of the patient. It is important that you seek treatment from a doctor who is experienced in providing Cresp Onco 200 Injection therapy. Follow all the directions strictly.
Q. Other than pure red cell aplasia (PRCA), can there be other reasons for not responding to Cresp Onco 200 Injection?
You may not respond to Cresp Onco 200 Injection if you have deficiencies of iron, folic acid, or vitamin B12. It is important that you take measures to correct these deficiencies. Other reasons behind not responding to the treatment could be bleeding, infections, inflammation, and bone marrow fibrosis. Therefore, consult our doctor regarding the same.
Q. Can Cresp Onco 200 Injection be used in children?
Yes, Cresp Onco 200 Injection is used to treat anemia due to chronic kidney disease in children who are above 1 year of age. The effectiveness of Cresp Onco 200 Injection and side effects seen in children are similar to adults. However, consult your doctor if you are not sure.
Q. Can Cresp Onco 200 Injection affect blood pressure?
Yes, Cresp Onco 200 Injection can affect blood pressure. During initial therapy with Cresp Onco 200 Injection, blood pressure should be monitored and those who have high blood pressure should take appropriate measures to control blood pressure. Your doctor may stop Cresp Onco 200 Injection if the blood pressure remains uncontrolled.
Q. Who should not take Cresp Onco 200 Injection?
Individuals who have cancer but have not been prescribed Cresp Onco 200 Injection by the doctor should not take it. Additionally, patients with uncontrolled hypertension (high blood pressure), patients with a history of anemia called pure red cell aplasia (PRCA) that starts after treatment with Cresp Onco 200 Injection or other erythropoietin medicines, and patients with a history of serious allergic reaction to this medicine should not take this medicine.
Benifits
In Treatment of Anemia due to cancer chemotherapy
Low red blood cell count is termed as anemia. Cancer treatment with chemotherapy often causes many side effects, one of the major ones being anemia. Cresp Onco 200 Injection stimulates the production of red blood cells in bone marrow and regulates the haemoglobin in the blood. This treats anemia in cancer patients receiving chemotherapy.
Side Effects
Abdominal pain
High blood pressure
Rash
Injection site pain
Breathlessness
Cough
Peripheral edema
Procedural hypotension (low blood pressure)
Convulsion
Thromboembolism
Angina (heart related chest pain)
Safety Profile
Alcohol:CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Cresp Onco 200 Injection. Please consult your doctor.
Pregnancy:CONSULT YOUR DOCTOR
Cresp Onco 200 Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding:CONSULT YOUR DOCTOR
Information regarding the use of Cresp Onco 200 Injection during breastfeeding is not available. Please consult your doctor.
Driving:SAFE
Cresp Onco 200 Injection does not usually affect your ability to drive.
Kidney:SAFE IF PRESCRIBED
Cresp Onco 200 Injection is safe to use in patients with kidney disease. No dose adjustment of Cresp Onco 200 Injection is recommended.
Liver:CAUTION
Cresp Onco 200 Injection should be used with caution in patients with liver disease. Dose adjustment of Cresp Onco 200 Injection may be needed. Please consult your doctor.
Refferences
Kaushansky K, Kipps TJ. Hematopoietic Agents: Growth Factors, Minerals, and Vitamins. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilmanโs: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1071-72.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 358-59.
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Darbepoetin alfa [Prescribing Information]. Thousand Oaks, California: Amgen Inc.; 2019. [Accessed 17 Jun. 2023] (online) Available from: View
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