Crizalk 250mg Capsule

Composition Crizotinib (250mg)
Rx Prescription Required
Pack box of 60 capsules
Storage Store below 30°C
Chemical Class Piperidine and Aminopyridine Derivative
Action Class Tyrosine Kinase Inhibitors (TKIs)
Habbit Forming
Manufacturer Pfizer Ltd
Manufacturer address The Capital, 1802, 18th Floor , Plot No. C-70, â??Gâ?? Block , Bandra Kurla Complex, Bandra East , Mumbai â?? 400051.

Crizalk 250mg Capsule is used in the treatment of non-small cell lung cancer that is locally advanced or has spread to other areas of the body.

Crizalk 250mg Capsule should be taken with food or without food, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Nausea, vomiting, edema (swelling), and diarrhea are some common side effects of this medicine. Some serious side effects that might occur which need doctor consultation include severe stomach pain, fever, chills, shortness of breath, fast heartbeat, partial or complete loss of vision or changes in bowel habits. Your doctor may perform some blood tests during the treatment to check for liver function.

Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Non-small cell lung cancer

Take this medicine in the dose and duration as advised by your doctor. Crizalk 250mg Capsule may be taken with or without food, but it is better to take it at a fixed time.

Crizalk 250mg Capsule is an anti-cancer medication. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells.

Q: What if you forget to take Crizalk Capsule?
A: If you miss a dose of Crizalk 250mg Capsule, skip it and continue with your normal schedule. Do not double the dose.

Crizalk 250mg Capsule helps in the treatment of non-small cell lung cancer that is locally advanced, or has spread to other areas of the body.

Take it at the same time each day, with or without food.

Diarrhea, nausea and vomiting may occur with Crizalk 250mg Capsule. Stay hydrated and inform your doctor if it persists.

It may cause dizziness or blurring of vision. Don’t drive or do anything requiring concentration until you know how it affects you.

Inform your doctor if you experience severe stomach pain, fever, chills, shortness of breath, fast heartbeat, partial or complete loss of vision or changes in bowel habits.

Your doctor may want you to have regular blood tests to monitor your liver function while you are having treatment with this medicine.

Do not take Crizalk 250mg Capsule if you are pregnant or breastfeeding. Use reliable methods of contraception to prevent pregnancy while taking this medicine.

Crizalk 250mg Capsule helps in the treatment of non-small cell lung cancer that is locally advanced, or has spread to other areas of the body.

Take it at the same time each day, with or without food.

Diarrhea, nausea and vomiting may occur with Crizalk 250mg Capsule. Stay hydrated and inform your doctor if it persists.

It may cause dizziness or blurring of vision. Don’t drive or do anything requiring concentration until you know how it affects you.

Inform your doctor if you experience severe stomach pain, fever, chills, shortness of breath, fast heartbeat, partial or complete loss of vision or changes in bowel habits.

Your doctor may want you to have regular blood tests to monitor your liver function while you are having treatment with this medicine.

Do not take Crizalk 250mg Capsule if you are pregnant or breastfeeding. Use reliable methods of contraception to prevent pregnancy while taking this medicine.

Q. How is Crizalk 250mg Capsule administered?

Crizalk 250mg Capsule is generally administered in the form of capsules to be taken orally.

Q. What is Crizalk 250mg Capsule used for?

Crizalk 250mg Capsule is used for treating non small-cell lung cancer caused due to a mutation or defect in a gene called as anaplastic lymphoma kinase in cancer cells in patients who have not responded to previous therapies.

Q. How does Crizalk 250mg Capsule work?

Crizalk 250mg Capsule works by inhibiting an enzyme called as tyrosine kinase that transmits the signal for growth and spread of cancer cells.

Dizziness

Fatigue

Edema (swelling)

Decreased appetite

Vision disorder

Gastrointestinal toxicity

Increased transaminase level in blood

Upper respiratory tract infection

Neuropathy

Abnormal blood cell count

Alcohol:CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Crizalk 250mg Capsule. Please consult your doctor.

Pregnancy:CONSULT YOUR DOCTOR

Crizalk 250mg Capsule is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding:CONSULT YOUR DOCTOR

Crizalk 250mg Capsule is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving:UNSAFE

Crizalk 250mg Capsule may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney:CAUTION

Crizalk 250mg Capsule should be used with caution in patients with severe kidney disease. Dose adjustment of Crizalk 250mg Capsule may be needed. Please consult your doctor.

Liver:CAUTION

Crizalk 250mg Capsule should be used with caution in patients with liver disease. Dose adjustment of Crizalk 250mg Capsule may be needed. Please consult your doctor.Use of Crizalk 250mg Capsule may not be advised in patients with the severe liver disease.

Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 331.
Crizotinib. Dublin, Ireland: Pfizer Ireland Pharmaceuticals; Aug. 2011. [Accessed 26 Mar. 2019] (online) Available from: View
Crizotinib. Bruxelles Belgium: Pfizer Europe; 23 Oct. 2012 [revised Feb. 2019]. [Accessed 26 Mar. 2019] (online) Available from: View
Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from: View