Cycloglob 50mg Tablet

Composition Cyclophosphamide (50mg)
Rx Prescription Required
Pack strip of 10 tablets
Storage Store in a refrigerator (2 – 8°C). Do not freeze.
Chemical Class Nitrogen Mustard Compounds
Action Class Alkylating Agents
Habbit Forming
Manufacturer Globela Pharma Pvt Ltd
Manufacturer address 357, G.I.D.C. Road No.3,Sachin, Surat – 394 230 ,Gujarat, India

Cycloglob 50mg Tablet is used in the treatment of different kinds of cancers. It is also used to treat kidney disease known as nephrotic syndrome in children after other treatments have not worked. It may be also used to treat other conditions, as determined by the doctor.

Cycloglob 50mg Tablet should be taken with food preferably in morning but at the same time every day to get the most benefit. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include vomiting, nausea, hair loss, fever, and blood in urine. If they do not go away or get worse, tell your doctor. There may be ways of preventing or reducing these effects. It is very strong medicine and some people may develop serious side effects while taking it. This medicine may lower your ability to fight infections and lead to problems with your blood, liver or kidneys. Your doctor will advise you regular blood tests to check for these. It is advised that you drink extra fluids so that you pass more urine. This will help prevent bladder and kidney problems and keep your kidneys working well.

Before taking it, tell your doctor if you have liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. It may harm your baby. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Cancer

Nephrotic syndrome

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Cycloglob 50mg Tablet is to be taken with food.

Cycloglob 50mg Tablet is an anti-cancer medication. It is an alkylating agent which works by damaging the genetic material (DNA and RNA) of the cancer cells, thereby stopping their growth and multiplication. This is how it works against cancer.

Q: What if you forget to take this medicine?
A:

Cycloglob 50mg Tablet helps in the treatment of cancer.

Drink plenty of fluids or urinate frequently to prevent urinary problems while taking this medication.

Take it with food if you experience irritation of the stomach, preferably in the morning.

Your doctor may get regular blood tests to monitor your blood counts while on treatment with this medication.

You are more likely to get sick or heal slower while taking this medication. Talk to your doctor before getting any vaccines.

Contact your doctor immediately if you experience difficulty in urinating or blood in urine while on treatment with this medication.

Do not take Cycloglob 50mg Tablet if you are pregnant or breastfeeding.

Use effective contraception method to prevent pregnancy while taking this medicine.

Cycloglob 50mg Tablet helps in the treatment of cancer.

Drink plenty of fluids or urinate frequently to prevent urinary problems while taking this medication.

Take it with food if you experience irritation of the stomach, preferably in the morning.

Your doctor may get regular blood tests to monitor your blood counts while on treatment with this medication.

You are more likely to get sick or heal slower while taking this medication. Talk to your doctor before getting any vaccines.

Contact your doctor immediately if you experience difficulty in urinating or blood in urine while on treatment with this medication.

Do not take Cycloglob 50mg Tablet if you are pregnant or breastfeeding.

Use effective contraception method to prevent pregnancy while taking this medicine.

Q. Can Cycloglob 50mg Tablet cause infertility?

Yes, Cycloglob 50mg Tablet can cause infertility in both men and women. It may interfere with the normal menstrual cycle in women and may stop sperm production in men. If you are considering becoming parents after the treatment please discuss this with your doctor. Talk to your doctor about cryopreservation (freezing) of sperm or eggs prior to treatment because of the possibility of irreversible infertility due to therapy with Cycloglob 50mg Tablet.

Q. Do I need to avoid sun exposure during treatment with Cycloglob 50mg Tablet?

No, there is no evidence that you need to avoid sun exposure while on Cycloglob 50mg Tablet. Skin and nail discoloration are reported rarely with Cycloglob 50mg Tablet.

Q. Can Cycloglob 50mg Tablet cause cancer?

Cancer medicines and radiation therapy can increase the risk of developing other cancers. These may not develop soon and may take a number of years after the completion of your treatment. The risk of developing cancer with Cycloglob 50mg Tablet is high in the urinary bladder. Other rare cancers that may occur with use of Cycloglob 50mg Tablet include Acute leukemia, Myelodysplastic syndrome, and cancer of the ureters.

Q. Is Cycloglob 50mg Tablet chemotherapy medicine?

Yes, Cycloglob 50mg Tablet is a chemotherapy medicine, it belongs to the class of alkylating agents. It works by killing cancer cells. It is also known as cytotoxic medicine.

Q. Can Cycloglob 50mg Tablet be used for non-cancer condition?

Yes, Cycloglob 50mg Tablet can be used to treat nephrotic syndrome (a disease that is caused by damage to the kidneys) in children whose disease has not improved, has gotten worse, or has come back after taking other medications. Along with that, it can be used in children who experienced intolerable side effects with other medications. However, in adults, the safety and effectiveness of Cycloglob 50mg Tablet for nephrotic syndrome has not been established.

Q. Can Cycloglob 50mg Tablet causes weight loss?

Yes, Cycloglob 50mg Tablet may cause weight loss because of reduced appetite. This reduction in weight could be due to underlying cancer. Consult your doctor, if weight loss is worrying you.

Q. Can Cycloglob 50mg Tablet cause infertility?

Yes, Cycloglob 50mg Tablet can cause infertility in both men and women. It may interfere with the normal menstrual cycle in women and may stop sperm production in men. If you are considering becoming parents after the treatment please discuss this with your doctor. Talk to your doctor about cryopreservation (freezing) of sperm or eggs prior to treatment because of the possibility of irreversible infertility due to therapy with Cycloglob 50mg Tablet.

Q. Do I need to avoid sun exposure during treatment with Cycloglob 50mg Tablet?

No, there is no evidence that you need to avoid sun exposure while on Cycloglob 50mg Tablet. Skin and nail discoloration are reported rarely with Cycloglob 50mg Tablet.

Q. Can Cycloglob 50mg Tablet cause cancer?

Cancer medicines and radiation therapy can increase the risk of developing other cancers. These may not develop soon and may take a number of years after the completion of your treatment. The risk of developing cancer with Cycloglob 50mg Tablet is high in the urinary bladder. Other rare cancers that may occur with use of Cycloglob 50mg Tablet include Acute leukemia, Myelodysplastic syndrome, and cancer of the ureters.

Q. Is Cycloglob 50mg Tablet chemotherapy medicine?

Yes, Cycloglob 50mg Tablet is a chemotherapy medicine, it belongs to the class of alkylating agents. It works by killing cancer cells. It is also known as cytotoxic medicine.

Q. Can Cycloglob 50mg Tablet be used for non-cancer condition?

Yes, Cycloglob 50mg Tablet can be used to treat nephrotic syndrome (a disease that is caused by damage to the kidneys) in children whose disease has not improved, has gotten worse, or has come back after taking other medications. Along with that, it can be used in children who experienced intolerable side effects with other medications. However, in adults, the safety and effectiveness of Cycloglob 50mg Tablet for nephrotic syndrome has not been established.

Q. Can Cycloglob 50mg Tablet causes weight loss?

Yes, Cycloglob 50mg Tablet may cause weight loss because of reduced appetite. This reduction in weight could be due to underlying cancer. Consult your doctor, if weight loss is worrying you.

Hair loss

Nausea

Infection

Diarrhea

Vomiting

Decreased white blood cell count (neutrophils)

Decreased white blood cell count (lymphocytes)

Myelosuppression

Cystitis

Microhematuria

Alcohol:UNSAFE

It is unsafe to consume alcohol with Cycloglob 50mg Tablet.

Pregnancy:CONSULT YOUR DOCTOR

Cycloglob 50mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding:UNSAFE

Cycloglob 50mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving:UNSAFE

Cycloglob 50mg Tablet may cause side effects which could affect your ability to drive.Cycloglob 50mg Tablet may cause undesirable effects (e.g., dizziness, blurred vision, visual impairment) which could affect the ability to drive.

Kidney:CAUTION

Cycloglob 50mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Cycloglob 50mg Tablet may be needed. Please consult your doctor.

Liver:CAUTION

Cycloglob 50mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Cycloglob 50mg Tablet may be needed. Please consult your doctor.

Lake DF, Briggs AD, Akporiaye ET. Immunopharmacology. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 975.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 335-38.
Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 26 Mar. 2019] (online) Available from: View
Cyclophosphamide monohydrate. Norfolk, UK: Baxter Healthcare Ltd.; 2004 [revised 9 Dec. 2016]. [Accessed 26 Mar. 2019] (online) Available from: View