Cycram 500mg Injection

Composition Cyclophosphamide (500mg)
Rx Prescription Required
Pack vial of 1 Injection
Storage Store in a refrigerator (2 – 8°C). Do not freeze.
Chemical Class Nitrogen Mustard Compounds
Action Class Alkylating agent
Habbit Forming No
Manufacturer Vhb Life Sciences Inc
Manufacturer address 50-AB, Government Industrial Estate, Charkop Naka, Kandivali West , Mumbai – 400067, Maharashtra, India

Cycram 500mg Injection is given as an injection into a vein by the healthcare professional, but better if injected at the same time every day. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include vomiting, nausea, hair loss, fever, and blood in urine. If they do not go away or get worse, tell your doctor. There may be ways of preventing or reducing these effects. It is very strong medicine and some people may develop serious side effects while taking it. This medicine may lower your ability to fight infections and lead to problems with your blood, liver or kidneys. Your doctor will advise you regular blood tests to check for these. It is advised that you drink extra fluids so that you pass more urine. This will help prevent bladder and kidney problems and keep your kidneys working well.

Before taking it, tell your doctor if you have liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Cancer
Nephrotic syndrome

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Cycram 500mg Injection is an anti-cancer medication. It is an alkylating agent which works by damaging the genetic material (DNA and RNA) of the cancer cells, thereby stopping their growth and multiplication. This is how it works against cancer.

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Cycram 500mg Injection helps in the treatment of cancer.

It is injected into the vein by a doctor or healthcare professional.

Drink plenty of fluids or urinate frequently to prevent urinary problems while taking this medication.

Your doctor may get regular blood tests to monitor your blood counts while on treatment with this medication.

You are more likely to get sick or heal slower while taking this medication. Talk to your doctor before getting any vaccines.

Contact your doctor immediately if you experience difficulty in urinating or blood in urine while on treatment with this medication.

Do not take Cycram 500mg Injection if you are pregnant or breastfeeding.

Use effective contraception method to prevent pregnancy while taking this medicine.

Q. Can Cycram 500mg Injection cause infertility?

Yes, Cycram 500mg Injection can cause infertility in both men and women. It may interfere with the normal menstrual cycle in women and may stop sperm production in men. If you are considering becoming parents after the treatment please discuss this with your doctor. Talk to your doctor about cryopreservation (freezing) of sperm or eggs prior to treatment because of the possibility of irreversible infertility due to therapy with Cycram 500mg Injection.

Q. Do I need to avoid sun exposure during treatment with Cycram 500mg Injection?

No, there is no evidence that you need to avoid sun exposure while on Cycram 500mg Injection. Skin and nail discoloration are reported rarely with Cycram 500mg Injection.

Q. Can Cycram 500mg Injection cause cancer?

Cancer medicines and radiation therapy can increase the risk of developing other cancers. These may not develop soon and may take a number of years after the completion of your treatment. The risk of developing cancer with Cycram 500mg Injection is high in the urinary bladder. Other rare cancers that may occur with use of Cycram 500mg Injection include Acute leukemia, Myelodysplastic syndrome, and cancer of the ureters.

Q. Is Cycram 500mg Injection chemotherapy medicine?

Yes, Cycram 500mg Injection is a chemotherapy medicine, it belongs to the class of alkylating agents. It works by killing cancer cells. It is also known as cytotoxic medicine.

Q. Can Cycram 500mg Injection be used for non-cancer condition?

Yes, Cycram 500mg Injection can be used to treat nephrotic syndrome (a disease that is caused by damage to the kidneys) in children whose disease has not improved, has gotten worse, or has come back after taking other medications. Along with that, it can be used in children who experienced intolerable side effects with other medications. However, in adults, the safety and effectiveness of Cycram 500mg Injection for nephrotic syndrome has not been established.

Q. Can Cycram 500mg Injection causes weight loss?

Yes, Cycram 500mg Injection may cause weight loss because of reduced appetite. This reduction in weight could be due to underlying cancer. Consult your doctor, if weight loss is worrying you.

In Cancer

Cycram 500mg Injection helps to treat certain kinds of cancer. It may be used alone or in combination with other medicines to treat cancer in various parts of the body. Cycram 500mg Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

In Nephrotic syndrome

Nephrotic syndrome is a kidney disorder that causes your body to pass too much protein in your urine accompanied with excessive swelling over various parts of the body such as around the eyes and in the feet and ankles. Cycram 500mg Injection works by suppressing the immune system thereby reducing inflammation and swelling that occur in nephrotic syndrome. It reduces the protein in the urine and also helps in getting rid of the extra fluid, thereby relieving the swelling over different parts of the body. This helps to restore the normal kidney function and prevents further damage to the kidneys.show moreshow less

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Decreased white blood cell count (neutrophils)

Diarrhea

Blood in urine

Fever

Hair loss

Nausea

Vomiting

Alcohol:UNSAFE

It is unsafe to consume alcohol with Cycram 500mg Injection.

Pregnancy:CONSULT YOUR DOCTOR

Cycram 500mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding:UNSAFE

Cycram 500mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving:UNSAFE

Cycram 500mg Injection may cause side effects which could affect your ability to drive.Cycram 500mg Injection may cause undesirable effects (e.g., dizziness, blurred vision, visual impairment) which could affect the ability to drive.

Kidney:CAUTION

Cycram 500mg Injection should be used with caution in patients with severe kidney disease. Dose adjustment of Cycram 500mg Injection may be needed. Please consult your doctor.

Liver:CAUTION

Cycram 500mg Injection should be used with caution in patients with liver disease. Dose adjustment of Cycram 500mg Injection may be needed. Please consult your doctor.

Lake DF, Briggs AD, Akporiaye ET. Immunopharmacology. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 975.

Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 335-38.

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