Composition Ketoconazole (2% w/v)
Rx
Pack bottle of 50 ml Shampoo
Storage Store below 30ยฐC
Chemical Class Azole derivatives {Imidazoles}
Action Class Fungal ergosterol synthesis inhibitor
Habbit Forming No
Manufacturer Cipla Ltd
Manufacturer address Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013

Danfree 2% Shampoo
Danfree 2% Shampoo is an antifungal medicine used to treat fungal infections of the skin. It works by killing the fungus that causes the infections. It kills fungi by destroying the fungal cell membrane.
Basic Info
Description
Danfree 2% Shampoo should be used in the dose and duration as prescribed by your doctor. This medicine should be used regularly to get the most benefit from it. Do not use more than you need, it will not clear your condition faster and may only increase the side effects. Do not use it for longer than your doctor has told you to and let him or her know if your condition does not improve after 2 to 4 weeks of treatment. Make sure not to leave it on the scalp for more than 5 minutes.
The most common side effects of using this medicine include dryness, hair discoloration, and abnormal hair texture. These are not usually serious, but you should call your doctor if you think you might have a severe allergic reaction. Signs of this include rash, swelling of the lips, throat or face, swallowing or breathing problems, feeling dizzy or faint, and nausea. Get emergency help if this happens. Avoid direct contact with your eyes. In the case of direct contact, wash your eyes with water, and seek immediate medical attention.
It is not likely that other medicines you take by mouth or injection will affect the way this medicine works, but talk to your doctor before using it if you have recently used another cream that contains a steroid or had an allergic reaction to another antifungal medicine. This medicine should only be used if it is clearly needed if you are pregnant or breastfeeding. Ask your doctor if it is safe.
Uses
Treatment of Fungal infections
How To Use
Use it as advised by your doctor or check the label for directions before use.
MOA
Danfree 2% Shampoo is an antifungal medication. It kills and stops the growth of the fungi by destroying its cell membrane, thereby treating your skin infection.
What If
If you miss a dose of Danfree 2% Shampoo, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Drug Tips
Danfree 2% Shampoo is used for the treatment and prevention of fungal infections of the skin and scalp such as dandruff.
Leave the shampoo on for three to five minutes before rinsing.
Take care to avoid getting it in your eyes. If accidental exposure occurs, rinse immediately with plenty of water.
Your usual shampoo can be used as necessary between treatment with Danfree 2% Shampoo.
Faqs
Q. What is Danfree 2% Shampoo? What is it used for?
Danfree 2% Shampoo is an antifungal medication used to control scaling, flaking and itching caused by dandruff. Dandruff is caused by excessive growth of Pityrosporum orbiculare (Malassezia furfur), which is part of normal skin flora. It is also used to treat irregular white or brown patches which occur on the body and sometimes appear after being in the sun (tinea/pityriasis versicolor). Regular application of Danfree 2% Shampoo on the scalp relieves itching and discomfort in people suffering from dandruff.
Q. How often should I use Danfree 2% Shampoo?
If you are using it to treat dandruff, you should use it only twice weekly and if you are using it to prevent dandruff, then use it once weekly. Do not use Danfree 2% Shampoo more often than directed.
Q. How should I apply Danfree 2% Shampoo?
You should first wash your hair or affected area thoroughly with water. Then apply a small amount of Danfree 2% Shampoo on the scalp. Massage properly to form lather. Leave it for 3-5 minutes, then thoroughly rinse with water. If you have long and thick hair, you can wash with your usual shampoo first and then use Danfree 2% Shampoo.
Q. Can Danfree 2% Shampoo be used in kids?
No, Danfree 2% Shampoo is not approved for kids and the safety in the children is yet to be known. Refrain from self-medicating this medication in children or yourself and consult your doctor for advice.
Q. I have started using Danfree 2% Shampoo. By when can I expect to start seeing the improvements?
The symptoms of the infection, such as itching or soreness, should improve within a few days of treatment. However, the signs such as redness and scaling may take longer to disappear. Do not stop applying this medicine before the duration advised by your doctor, even if you feel better.
Q. Can Danfree 2% Shampoo affect vision if it gets into the eye while washing hair?
Be careful while washing your hair and do not let the shampoo get into the eye. However, if it accidentally enters the eye, do not worry and wash your eyes gently with water.
Q. Is Danfree 2% Shampoo an antibacterial agent?
No, Danfree 2% Shampoo is not an antibacterial agent. It is an antifungal medicine which is used for the treatment of dandruff. Pityrosporum orbiculare (Malassezia furfur) is a fungus which plays an important role in the development of dandruff. Danfree 2% Shampoo being an antifungal agent is very effective against the fungal infection causing the dandruff.
Q. What if someone accidentally swallows Danfree 2% Shampoo?
Danfree 2% Shampoo is meant for external use only and you should use it carefully so that it does not get into the mouth. Accidental swallowing is normally harmless but if you are worried, you should contact your doctor immediately.
Benifits
In Treatment of Fungal infections
Danfree 2% Shampoo is an antifungal medicine. It works by killing and stopping the growth of fungus that is causing the infection. It helps treat infections of the scalp and hairThe dose and duration of treatment will depend on what you are being treated for. Make sure you complete the full course of treatment. This will ensure that the infection is completely cured and prevent it from returning.
Side Effects
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if youโre worried about them
Abnormal hair texture
Hair discoloration
Dryness
Safety Profile
Alcohol:
No interaction found/established
Pregnancy:
No interaction found/established
Breast feeding:
No interaction found/established
Driving:
No interaction found/established
Kidney:
No interaction found/established
Liver:
No interaction found/established
Refferences
Schimmer BP, Funder JW. ACTH, Adrenal Steroids, and Pharmacology of the Adrenal Cortex. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilmanโs: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1233.
Bennett JE. Antifungal Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilmanโs: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. p. 1576.
Chrousos GP. Adrenocorticosteroids & Adrenocortical Antagonists. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 693.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 758-59.

