Daunoplus 20mg Injection is used for the treatment of blood cancer (leukemia). It works by interfering with the growth of cancer cells, which are eventually destroyed.
Daunoplus 20mg Injection is given under the supervision of a healthcare professional and should not be self-administered. It might be given as a single therapy or in combination with some other medication. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. You should avoid drinking alcohol as it may increase your risk of liver damage.
The most common side effects of this medicine include nausea, vomiting, low platelet count, ulcer, loss of appetite and difficulty while breathing. If they do not go away or get worse, tell your doctor. There may be ways of preventing or reducing these effects. It is very strong medicine and some people may develop serious side effects while taking it. This medicine may lower your ability to fight infections and lead to problems with your blood, liver or kidneys. Your doctor will advise you regular blood tests to check for these.
Before taking it, tell your doctor if you have liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. It may harm your baby. You and your partner should avoid becoming pregnant or fathering a child for several months after your treatment with it has stopped. Your doctor may perform several tests such as blood tests, ECG, and physical examinations both before and during treatment with this medicine.
Blood cancer
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Daunoplus 20mg Injection is an anti-cancer medication. It works by damaging the genetic material (DNA) of the cancer cells and stops their growth and multiplication.
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Daunoplus 20mg Injection is given as an injection into the vein under the supervision of a doctor.
Do not skip any dose and complete the course as suggested by your doctor.
Use an effective method of birth control to avoid pregnancy while taking this medication.
Your doctor may get regular blood tests done to monitor your electrolyte levels, liver function, blood cell count in your blood.
You may be monitored with ECG before and after starting the treatment.
Let your doctor know if you experience fever, chills and some kind of infection during the treatment.
Q. Is Daunoplus 20mg Injection a vesicant?
Yes. Daunoplus 20mg Injection is a vesicant (irritant) and can cause severe tissue damage upon extravasation (leaking of injected Daunoplus 20mg Injection into the surrounding tissues from the site of administration) when injected.
Q. What is Daunoplus 20mg Injection used for?
Daunoplus 20mg Injection is used in combination with other cancer medications to subside the progression of different types of blood cancers such as cancer of the white blood cells (acute myeloid and acute lymphocytic leukemia).
Q. How is Daunoplus 20mg Injection administered?
Daunoplus 20mg Injection comes as a solution or powder to be added to fluid and injected into a vein (intravenous) along with other chemotherapy medications. It is given as an injection by a cancer specialized doctor (oncologist) who is experienced in giving chemotherapy medications for cancer in a hospital or a clinic.
Q. How often is Daunoplus 20mg Injection given?
The frequency and duration of Daunoplus 20mg Injection treatment depends on the other chemotherapy medications you are taking, how well your body responds to them, and the type of cancer you have. Your doctor will decide the dose and frequency for you based on different parameters. For any doubts, consult your doctor.
Q. How does Daunoplus 20mg Injection work?
Daunoplus 20mg Injection is an anti-cancer drug which belongs to the class of medicines called anthracycline cytotoxic antibiotics. The exact mechanism for its clinical effects is not clear; however multiple mechanisms directly interfering with important DNA processes and cell division are thought to be responsible for slowing or stopping the growth of cancer cells.
In Blood cancer
Blood cancer, also called leukemia, is a cancer of the blood-forming tissues, that decreases the body’s ability to fight infection. Daunoplus 20mg Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Breathing problems
Stomatitis (Inflammation of the mouth)
Febrile neutropenia
Mucosal inflammation
Diarrhea
Chills
Anemia (low number of red blood cells)
Fatigue
Decreased blood cells (red cells, white cells, and platelets)
Fever
Hair loss
Decreased white blood cell count
Loss of appetite
Abdominal pain
Ulcer
Low blood platelets
Vomiting
Nausea
Alcohol:CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Daunoplus 20mg Injection. Please consult your doctor.
Pregnancy:CONSULT YOUR DOCTOR
Daunoplus 20mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding:UNSAFE
Daunoplus 20mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving:UNSAFE
Daunoplus 20mg Injection may cause side effects which could affect your ability to drive.
Kidney:CAUTION
Daunoplus 20mg Injection should be used with caution in patients with kidney disease. Dose adjustment of Daunoplus 20mg Injection may be needed. Please consult your doctor.Use of Daunoplus 20mg Injection is not recommended in patients with severe kidney disease.
Liver:CAUTION
Daunoplus 20mg Injection should be used with caution in patients with liver disease. Dose adjustment of Daunoplus 20mg Injection may be needed. Please consult your doctor.Use of Daunoplus 20mg Injection is not recommended in patients with severe liver disease.
Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 952.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 362-63.
Daunorubicin hydrochloride. Surrey, UK: Zentiva; 1994 . view
Drugs.com. Daunorubicin Pregnancy and Breastfeeding Warnings. view
Central Drugs Standard Control Organisation . view
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