Defogen 1mg Tablet

Composition Estriol (1mg)
Rx Prescription Required
Pack strip of 10 tablets
Storage Store below 30°C
Chemical Class Estrogens Derivatives
Action Class Estrogens
Habbit Forming
Manufacturer Incepta Pharma
Manufacturer address Parshvnath Tower, Subhash Chowk, Mem Nagar, Ahmedabad-302002 (Gujarat)

Defogen 1mg Tablet is a female hormone that is identical to estrogen. It is used as a hormone replacement therapy (HRT) to treat symptoms associated with menopause (hot flushes, vaginal dryness and itching), estrogen deficiency (hypoestrogenism), and thinning of bones (osteoporosis).

In some cases, Defogen 1mg Tablet is also used to treat breast cancer and prostate cancer along with other anticancer medicines. The medicine is to be swallowed with water. It can be taken with or without food, but remember to take it at a fixed time each day for better efficacy. The dose and duration will be decided by your doctor so that you get the right amount to control your symptoms. If you have missed a dose, take it as soon as you remember it. Do not skip any dose and finish the full course of treatment. The treatment should not be stopped abruptly without consulting your doctor as this may affect the potency of this medicine.

The most common side effects of this HRT are headache, breast pain, irregular vaginal bleeding or spotting, abdominal cramps or bloating, nausea, vomiting, and hair loss. Some of the warning signs and symptoms that need immediate medical attention are breast lumps, unusual vaginal bleeding, dizziness and faintness, severe headaches, chest pain, shortness of breath, pains in your legs, etc.

Before taking this medicine, it is important to tell your doctor if you are taking or have recently taken any other medicines for the same disease or other diseases. Before you initiate with this HRT, you must consult the doctor if you have a history of unexplained vaginal bleeding or if you have ever had a blood clot in your legs or your lungs. If you are pregnant or breastfeeding, you should tell your doctor before taking this medicine. Your doctor may suggest you some diagnostic or laboratory tests to know the effects and side effects of this medicine on your body.

Treatment of Prostate cancer

Hormone replacement therapy

Prevention of Breast cancer

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Defogen 1mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

Defogen 1mg Tablet contains a hormone called estrogen (female sex hormone). It works by replacing estrogen that is normally produced by the body.

Q: What if you forget to take this medicine?
A:

You have been prescribed Defogen 1mg Tablet as a part of hormone replacement therapy to relieve symptoms of menopause.

It may also be used for preventing osteoporosis in postmenopausal women who are at high risk of fractures.

Take it at the same time everyday to help you remember to take it.

Inform your doctor if you experience any unusual vaginal bleeding or spotting, abnormal vaginal discharge or vaginal discomfort while taking Defogen 1mg Tablet.

It may increase the risk of breast cancer. Have regular breast examinations.

Stop taking this medicine and inform your doctor immediately if you notice unexplained swelling and pain in your limbs, shortness of breath, chest pain, or changes in vision. These could be symptoms of a blood clot in a vein

Q. What is Defogen 1mg Tablet and what is it used for?

Defogen 1mg Tablet tablet contains a medicine called Estriol which is an estrogen hormone. It helps in treating estrogen deficiency symptoms like hot flushes (red and warm face), vaginal dryness in women.  It is also used to prevent osteoporosis (thinning and weakening of bone) in postmenopausal women, who are at high risk of fractures and can not take other preventive medicines for osteoporosis.

Q. When and how to take Defogen 1mg Tablet?

Take Defogen 1mg Tablet as per the advise by your doctor. However, you must try to take Defogen 1mg Tablet tablet at the same time of each day, to ensure the consistent levels of medicine in your body.

Q. What if I miss to take Defogen 1mg Tablet?

If you miss a dose, you should take it as soon as possible. If the dose was missed by more than 12 hours, you should not take the missed dose and simply continue the usual dosing schedule.

Q. What are the most common side effects which I may experience while taking Defogen 1mg Tablet?

The common side effects associated with Defogen 1mg Tablet are lower abdominal pain, periods pain, breast tenderness, endometrial hyperplasia (thickening of uterus lining) and vaginal discharge. Most of these symptoms are temporary. However, if they persist, check with your doctor as soon as possible.

In Treatment of Prostate cancer

Prostate cancer is a common type of cancer in males, but it is highly treatable in the early stages. It starts in the prostate gland, which is located between the penis and the bladder. Defogen 1mg Tablet helps treat prostate cancer by decreasing or stopping the growth of cancer cells. This further gives relief from the symptoms of prostate cancer such as difficulty in passing urine. Take Defogen 1mg Tablet as prescribed by your doctor.

Headache

Breast pain

Irregular vaginal bleeding

Abdominal cramp

Bloating

Hair loss

Nausea

Vomiting

Weight loss

Alcohol:CAUTION

Caution is advised when consuming alcohol with Defogen 1mg Tablet. Please consult your doctor.

Pregnancy:UNSAFE

Defogen 1mg Tablet is highly unsafe to use during pregnancy. Seek your doctor’s advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.

Breast feeding:UNSAFE

Defogen 1mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving:SAFE

Defogen 1mg Tablet does not usually affect your ability to drive.

Kidney:CAUTION

Defogen 1mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Defogen 1mg Tablet may be needed. Please consult your doctor.

Liver:CAUTION

Defogen 1mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Defogen 1mg Tablet may be needed. Please consult your doctor.

Masters SB. Hypothalmic & Pituitary Hormones. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 701-702.
ScienceDirect. Estriol. [Accessed 03 Apr. 2019] (online) Available from: View
Estriol [Prescribing Information]. Madison, NJ: Intervet International B.V.; 2020. [Accessed 10 June 2024] (online) Available from: View