Dermotrex 1% Gel

Composition Methotrexate (1% w/w)
Rx Prescription Required
Pack tube of 30 gm Gel
Storage Store below 30°C
Chemical Class Glutamic Acid Derivative
Action Class Antimetabolite- Methotrexate
Habbit Forming No
Manufacturer East West Pharma
Manufacturer address No. 10, 2nd Cross, Maravaneri, Salem – 636007, Tamil Nadu.

Dermotrex 1% Gel is only meant for external use and should be used as advised by your doctor. Your doctor will decide what dose is necessary and how often you need to use it. Do not stop using the medicine without first checking with your doctor. You should use it exactly as your doctor has advised.

The most common side effects of this medicine include nausea, vomiting, loss of appetite, and abdominal pain. If they do not go away or get worse, tell your doctor. There may be ways of preventing or reducing these effects. Before using it, tell your doctor if you have liver or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. It can cause harm to your baby.

Treatment of Rheumatoid arthritis
Treatment of Psoriasis

This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the gel. Wash your hands after applying, unless hands are the affected area.

Dermotrex 1% Gel is an immunosuppressant. In psoriasis, it works by slowing down the rapid growth of skin cells.

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Take it once a week, on the same day every week.

Always take folic acid as advised by your doctor. This will help lessen the side effects of this medicine.

It may take 6 to 8 weeks for Dermotrex 1% Gel to work. Keep taking the medication as prescribed.

Avoid drinking alcohol while taking this medicine as it may increase the risk of side effects.

It can be harmful to an unborn baby. Avoid pregnancy for at least 6 months after your last dose.

Drink plenty of liquids to stay hydrated while taking this  medication.

Q. Is Dermotrex 1% Gel effective?

Dermotrex 1% Gel is effective if used in the dose and duration advised by your doctor. Do not stop using it even if you see improvement in your condition. If you stop using Dermotrex 1% Gel too early, the symptoms may return or worsen.

Q. How to use Dermotrex 1% Gel?

Before using Dermotrex 1% Gel, clean and dry the affected area. Gently and thoroughly massage it into the skin. Be careful not to get the medication in your eyes or mouth. If Dermotrex 1% Gel gets in your eyes accidentally, wash with plenty of water and call your doctor if your eyes are irritated.

Q. What precautions do I need to take while using Dermotrex 1% Gel?

Be careful not to get Dermotrex 1% Gel into your eyes or mouth. If you happen to get it in your eyes, rinse off with plenty of water immediately and contact your doctor. You must not use Dermotrex 1% Gel if you are allergic to it or any of its ingredients. Tell your doctor if you notice any allergic reaction while using it for the first time. Inform your doctor if you are taking any medicines regularly to prevent any allergic reaction with other medicines. Do not cover the area being treated with Dermotrex 1% Gel with a bandage, as this may increase absorption of this medicine and increase the side effects. Do not use more than what is recommended to relieve your symptoms faster. Using more than what is advised will only increase the side effects. Let your doctor know if you are planning to conceive to avoid any harm to the baby. Pregnant and breastfeeding mothers should use Dermotrex 1% Gel only if prescribed by the doctor.

Q. What should I do if I forget to use Dermotrex 1% Gel?

If you forget to use Dermotrex 1% Gel, do not worry and continue using Dermotrex 1% Gel as soon as you remember. Do not double the dose to make up for the missed dose. However, if you are not sure and have any other doubts, please consult your doctor.

In Treatment of Rheumatoid arthritis

Dermotrex 1% Gel belongs to a group of medicines called antimetabolites. It may be used to treat severe rheumatoid arthritis if other treatments have already been tried and have not worked. It is not a first-line treatment. It works by reducing the body’s immune system, this decreases swelling, reduces pain, stiffness, and improves function. Take it exactly as prescribed and for as long as it is prescribed to get the most benefit. Do not take more than you should. It may take several months to become fully effective.

In Treatment of Psoriasis

Dermotrex 1% Gel belongs to a group of medicines called antimetabolites. It may be used to treat severe psoriasis when other treatments have not worked. Psoriasis is a condition where the skin cells in the body grow too quickly. Dermotrex 1% Gel works by killing these fast-growing cells. It is potent and very toxic medicine and you should discuss the risks and benefits with your doctor. Take it exactly as prescribed and for as long as it is prescribed to get the most benefit. DO NOT take more than you should. It may take several months to become fully effective. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.show moreshow less

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Mouth sore

Tiredness

Vomiting

Nausea

Loss of appetite

Indigestion

Abdominal pain

Alcohol:

No interaction found/established

Pregnancy:UNSAFE

Dermotrex 1% Gel is highly unsafe to use during pregnancy. Seek your doctor’s advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.

Breast feeding:UNSAFE

Dermotrex 1% Gel is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving:

No interaction found/established

Kidney:

No interaction found/established

Liver:

No interaction found/established

Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 944-46.

Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 887-90.

Drugs.com. Methotrexate Pregnancy and Breastfeeding Warnings. view