Composition Deferoxamine (500mg)
Rx Prescription Required
Pack vial of 1 Injection
Storage Store below 25ยฐC
Chemical Class Acetohydroxamic acids derivative
Action Class Iron chelating agents
Habbit Forming No
Manufacturer Novartis India Ltd
Manufacturer address Sandoz House, Shiv Sagar Estate, Worli Mumbai -400 018, India

Desferal 500mg Injection
Desferal 500mg Injection is a medicine used in the treatment of chronic iron overload caused due to frequent blood transfusion. It helps in removing the excess iron from the body and reduces the risk of it causing organ damage.
Basic Info
Description
Desferal 500mg Injection is generally administered by a healthcare professional. You should not self-administer this medicine.
Using of Desferal 500mg Injection may cause few side effects such as flushing (a sense of warmth in the face, ears, neck and trunk), rash, decreased blood pressure and abdominal pain. If the side effects persist or worsen, inform your doctor.
Uses
Iron overload
Transfusion dependent thalassemia
How To Use
Your doctor or nurse will give you this medicine. Kindly do not self administer.
MOA
Desferal 500mg Injection traps and removes excess iron which is then excreted mainly in the stools. This reduces the risk of organ damage.
What If
If you miss a dose of Desferal 500mg Injection, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Drug Tips
Desferal 500mg Injection is used to reduce excess iron from the body.
Desferal 500mg Injection may cause your urine to turn a red/brown color. This is the iron being removed from your body and is nothing for you to worry about as it is quite harmless.
If you are taking any antacid, take them 2 hours before or after Desferal 500mg Injection.
Desferal 500mg Injection may cause dizziness. It is advisable not to drive or operate any machinery until you feel normal again.
Inform your doctor if you have any liver or kidney disease.
Inform your doctor if you are pregnant or breastfeeding.ย
Faqs
Information not available at the moment. Please check back later.
Benifits
In Iron overload
Iron overload, as the name suggests, means excess of iron in the human body. Too much iron can cause organ damage, which can lead to conditions such as cancer, irregular heartbeat and cirrhosis of the liver. Symptoms are related to conditions that arise from iron overload such as high blood sugar levels (diabetes), darkening of the skin, abnormal heart rhythm or arthritis. By using Desferal 500mg Injection, this excess of iron can be decreased to safe levels by removing it from the body through stools. This helps to reduce the risk of organ damage and prevents further complications. Desferal 500mg Injection is given by a doctor or nurse and should not be self-administered. Follow your doctorโs instructions carefully to get maximum benefit.
Side Effects
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if youโre worried about them
Abdominal pain
Decreased blood pressure
Rash
Flushing (sense of warmth in the face, ears, neck and trunk)
Safety Profile
Alcohol:CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Desferal 500mg Injection. Please consult your doctor.
Pregnancy:CONSULT YOUR DOCTOR
Desferal 500mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding:SAFE IF PRESCRIBED
Desferal 500mg Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving:UNSAFE
Desferal 500mg Injection may cause side effects which could affect your ability to drive.If you experience dizziness or other central nervous disturbances, or impairment of vision with the use of Desferal 500mg Injection then you should refrain from driving a vehicle.
Kidney:CAUTION
Desferal 500mg Injection should be used with caution in patients with kidney disease. Dose adjustment of Desferal 500mg Injection may be needed. Please consult your doctor.Use of Desferal 500mg Injection is not recommended in patients with severe kidney disease.
Liver:CONSULT YOUR DOCTOR
There is limited information available on the use of Desferal 500mg Injection in patients with liver disease. Please consult your doctor.
Refferences
Byrns MC, Penning TM. Environmental Toxicology: Carcinogens and Heavy Metals. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilmanโs: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1875-76.
Kosnett MJ. Heavy Metal Intoxication & Chelators. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 1010.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 365-66.
Deferoxamine. Hurley, Maidenhead: Hospira UK Ltd.; 2001 . view
Mayo Clinic. Deferoxamine. view
Drugs.com. Deferoxamine. view
Deferoxamine. Stein, Switzerland: Novartis Pharma Stein AG; 2011. view

