Composition Deferasirox (500mg)
Rx Prescription Required
Pack bottle of 30 tablets
Storage Store below 30ยฐC
Chemical Class Triazole & benzoate derivative
Action Class Iron chelating agents
Habbit Forming No
Manufacturer Cipla Ltd
Manufacturer address Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013

Desirox 500 Tablet
Desirox 500 Tablet is a medicine used in the treatment of chronic iron overload caused by frequent blood transfusion. It helps remove the excess iron from the body and reduce the risk of it causing organ damage.
Basic Info
Description
Desirox 500 Tablet should be taken on an empty stomach. Take it in the exact dose and duration and take it regularly at a fixed time each day to get the maximum benefit from it.
Using of Desirox 500 Tablet may cause common side effects such as nausea, headache, constipation, diarrhea, and increased liver enzyme. If the side effects persist or worsen, inform your doctor.
Before using this medicine, let your doctor know if you have any kidney or liver diseases. Let your doctor also know about all the other medicines you are taking to ensure your safety.
Uses
Treatment of Iron overload
How To Use
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Desirox 500 Tablet is to be taken empty stomach.
MOA
Desirox 500 Tablet traps and removes excess iron which is then excreted mainly in the stools. This reduces the risk of organ damage.
What If
If you miss a dose of Desirox 500 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Drug Tips
Desirox 500 Tablet is used to reduce excess iron from the body.
Inform your doctor if you also have upper stomach pain, clay-colored stools, or jaundice (yellowing of your skin or the whites of your eyes).
Take an adequate amount of water while taking Desirox 500 Tablet.ย
Desirox 500 Tablet may cause dizziness. It is advisable not to drive or operate any machinery until you feel normal again.
If you are taking any antacid, take them 2 hours before or after Desirox 500 Tablet.
Inform your doctor if you have any liver or kidney disease.
Inform your doctor if you are pregnant or breastfeeding.
Faqs
Q. What is Desirox 500 Tablet used for?
Desirox 500 Tablet is used for removing excess iron from the body due to repeated blood transfusions in patients with beta thalassemia major (a blood disorder)
Q. How does Desirox 500 Tablet work?
Desirox 500 Tablet works by binding to excess iron in the blood and removing it from the body through stool.
Benifits
In Treatment of Iron overload
Iron overload, as the name suggests, means excess of iron in the human body. Too much iron can cause organ damage, which can lead to conditions such as cancer, irregular heartbeat and cirrhosis of the liver. Symptoms are related to conditions that arise from iron overload such as high blood sugar levels (diabetes), darkening of the skin, abnormal heart rhythm or arthritis. By using Desirox 500 Tablet, this excess of iron can be decreased to safe levels by removing it from the body through stools. This helps to reduce the risk of organ damage and prevents further complications. Take Desirox 500 Tablet as prescribed by the doctor to get the maximum benefit.
Side Effects
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if youโre worried about them
Diarrhea
Abdominal distension
Increased liver enzymes
Itching
Constipation
Abdominal pain
Rash
Vomiting
Headache
Nausea
Safety Profile
Alcohol:CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Desirox 500 Tablet. Please consult your doctor.
Pregnancy:CONSULT YOUR DOCTOR
Desirox 500 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding:SAFE IF PRESCRIBED
Desirox 500 Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving:UNSAFE
Desirox 500 Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney:UNSAFE
Desirox 500 Tablet is probably unsafe to use in patients with kidney disease and should be avoided. Please consult your doctor.
Liver:CAUTION
Desirox 500 Tablet should be used with caution in patients with liver disease. Dose adjustment of Desirox 500 Tablet may be needed. Please consult your doctor.Limited information is available on the use of Desirox 500 Tablet in these patients.
Refferences
Byrns MC, Penning TM. Environmental Toxicology: Carcinogens and Heavy Metals. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilmanโs: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1875-76.
Kosnett MJ. Heavy Metal Intoxication & Chelators. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 1010.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 365.
Deferasirox. Camberley, Surrey: Novartis Pharmaceuticals UK Ltd.; 2006 . view
Medscaape. Deferasirox. view
Deferasirox. Camberley, Surrey: Novartis Pharmaceuticals UK Ltd.; 2006 . view
Drugs.com. Deferasirox Pregnancy and Breastfeeding Warnings. view
Central Drugs Standard Control Organisation . view

