Doxipeg 20mg Injection

Composition Doxorubicin (Liposomal) (20mg)
Rx Prescription Required
Pack vial of 1 Injection
Storage Store in a refrigerator (2 – 8°C). Do not freeze.
Chemical Class Anthracycline Derivative
Action Class Alkaloids-cytotoxic agents
Habbit Forming No
Manufacturer Sarabhai Chemicals Ltd
Manufacturer address Shantisadan, Mirzapur Road, Ahmedabad -380001

Doxipeg 20mg Injection is used in the treatment of some kinds of cancer. It is also used in the treatment of breast cancer, where there is an increased cardiac risk. It can be used on its own, or sometimes given together with certain other medicines as part of combination chemotherapy.

Doxipeg 20mg Injection can be used in both adults and children. It is given as injection into vein with extreme caution by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. It makes contraceptive pills less effective, so it advised to use reliable contraception during and after 6 months of the treatment.The most common side effects of this medicine include nausea, vomiting, rash, weakness, low blood platelets. If they do not go away or get worse, tell your doctor. There may be ways of preventing or reducing these effects. It is very strong medicine and some people may develop serious side effects while taking it. This medicine may lead to problems with your blood, liver or heart. Your doctor will advise you regular blood tests to check for these.Before taking this medicine, let your doctor know if you have liver disease. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Tell your doctor if you are pregnant or breastfeeding.

Cancer

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Doxipeg 20mg Injection is an anti-cancer medication. It works by damaging the genetic material (DNA) of the cancer cells and stops their growth and multiplication.

Information not available at the moment. Please check back later.

Doxipeg 20mg Injection helps treat cancer of the breast, blood, and ovaries.

It is given through a drip into a vein (intravenous infusion) by a doctor or nurse.

It may make you feel tired or sleepy. Do not drive or do anything that requires mental focus until you know how it affects you.

Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and for 6 months after stopping treatment.

Inform your doctor if you notice sores, discolouration or any discomfort in your mouth.

Your doctor may get regular blood tests done to monitor your blood cells, liver, and heart function during treatment with this medicine.

Inform your doctor immediately if you notice any signs of infection such as fever, sore throat or rash.

Q. How does doxorubicin work?

Doxorubicin is anti-cancer or antineoplastic chemotherapy drug that belongs to a class of medication called anthracyclines. It slows down or stops the growth of cancer cells by interfering with DNA of the cancer cell.

Q. What is liposomal doxorubicin?

The molecules of doxorubicin are coated in a fatty capsule called as liposome. This liposome protects the body and allows the doxorubicin to remain in the blood circulation for a longer duration. This means that more amount of drug can be delivered to the cancer cells with less side effects.

In Cancer

Doxipeg 20mg Injection helps to treat certain kinds of cancer. It may be used alone or in combination with other medicines to treat cancer in various parts of the body. It relieves the symptoms of breast cancer such as breast lumps, bloody discharge from nipples or changes in the shape or texture of the breast. Doxipeg 20mg Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Painful blisters on hands and feet

Diarrhea

Stomatitis (Inflammation of the mouth)

Constipation

Anemia (low number of red blood cells)

Loss of appetite

Decreased white blood cell count (neutrophils)

Fever

Fatigue

Low blood platelets

Weakness

Rash

Vomiting

Nausea

Alcohol:CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Doxipeg 20mg Injection. Please consult your doctor.

Pregnancy:CONSULT YOUR DOCTOR

Doxipeg 20mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding:CONSULT YOUR DOCTOR

Information regarding the use of Doxipeg 20mg Injection during breastfeeding is not available. Please consult your doctor.

Driving:UNSAFE

Doxipeg 20mg Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney:SAFE IF PRESCRIBED

Doxipeg 20mg Injection is safe to use in patients with kidney disease. No dose adjustment of Doxipeg 20mg Injection is recommended.Caution is advised in patients with severe kidney disease as the information available is limited for use of this medicine in these patients.

Liver:CAUTION

Doxipeg 20mg Injection should be used with caution in patients with liver disease. Dose adjustment of Doxipeg 20mg Injection may be needed. Please consult your doctor.Use of Doxipeg 20mg Injection is not recommended in patients with severe liver disease.

Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1714-15.

Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 952.

Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 431-33.

Doxorubicin hydrochloride liposome. Bedford, Ohio: Ben Venue Laboratories, Inc.; 1995 . view

Doxorubicin hydrochloride. Beerse, Belgium: Janssen-Cilag International NV; 21 Jun. 1996 . . view

Drugs.com. Doxorubicin Pregnancy and Breastfeeding Warnings. . view

Central Drugs Standard Control Organisation . view