E Gest 300mg Tablet SR

E Gest 300mg Tablet SR is also prescribed along with estrogen as a part of hormonal replacement therapy for preventing endometrial hyperplasia (thickening of the lining of the uterus).  It should be taken without food, preferably in the evening or at bedtime. It should be taken at the same time each day to get the most benefit. You should continue taking it for as long as your doctor has told you to, even if you feel well. 

The most common side effects include abdominal bloating, abdominal pain, dizziness, headache, depression, breast tenderness, hot flushes, vaginal discharge, joint paint, and urinary incontinence. Side effects are more common during the first few weeks and usually lessen as your body gets used to the medicine. You may also experience bleeding or spotting between your periods, consult with your doctor if it happens frequently. If you experience dizziness or tiredness, avoid driving or activity which requires mental concentration. 

Before taking this medicine, inform your doctor if you have, or have had, breast cancer, unusual bleeding in the vagina, or liver disease. You will probably have several tests both before and during treatment to check your womb.  Also, tell your doctor what other medicines you are taking as some may affect, or be affected by, this medicine. 

Hormone replacement therapy
Female infertility

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. E Gest 300mg Tablet SR is to be taken empty stomach.

E Gest 300mg Tablet SR is a progesterone (female hormone). It works on the lining of the uterus and helps to establish and maintain pregnancy in infertile women. It helps in protecting the uterus from the negative effects of oestrogen when used for the treatment of postmenopausal symptoms.

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E Gest 300mg Tablet SR is used in the treatment of female infertility and as a part of hormone replacement therapy.

It regulates menstrual cycles, treats heavy bleeding, and prevents thickening of the uterus.

It is also used to restore menstruation in women with secondary amenorrhea (the absence of menstrual cycles).

It should be taken without food, preferably in the evening or at bedtime.

It may cause sleepiness or drowsiness. Don’t drive or do anything that requires mental focus until you know how E Gest 300mg Tablet SR affects you.

It may cause bleeding  or spotting in between menstrual periods. Let your doctor know if this occurs frequently.

Q. Can you take E Gest 300mg Tablet SR every day?

Yes, E Gest 300mg Tablet SR can be taken every day. It is usually prescribed to be taken once daily in the evening or at bedtime. The usual duration of prescription may vary from 10-12 days a month to 25 days a month. However, the number of days for which you will need to take this medicine in each cycle will be suggested by your doctor depending upon your health condition.

Q. Does E Gest 300mg Tablet SR cause weight gain?

Yes, taking E Gest 300mg Tablet SR may cause weight gain. The weight gain may be due to water retention and may not be a serious sign. However, contact your doctor in case your weight gain is worrying you. The risk of weight gain is generally less if E Gest 300mg Tablet SR is taken with estrogen as a combined pill. But, do not start any hormonal therapy without consulting your doctor.

Q. How is progesterone beneficial for fertility and pregnancy?

Progesterone is a very crucial hormone in fertility. It is the hormone secreted by the ovaries that helps prepare the uterus for pregnancy and maintain it. E Gest 300mg Tablet SR (form of progesterone) is given as a medicine in cases of infertility to support the uterus in preparing itself for the pregnancy and to prevent the abortions in some cases. It is also used to prevent premature labor.

In Hormone replacement therapy

Hormone Placement Therapy (HRT) is a treatment to relieve symptoms of menopause such as hot flushes, night sweats, mood swings, vaginal dryness and reduced sex drive. Since menopause can last for several years, this treatment can make a big improvement to your daily life and mood. You should use this medicine as it is prescribed, and for as long as it is prescribed by your doctor.

In Female infertility

E Gest 300mg Tablet SR contains progesterone, a female hormone that is important in the regulation of ovulation and menstruation. It is used to cause menstrual periods in women who have not reached menopause but are not having periods due to a lack of natural progesterone in the body. Progesterone helps to prepare the uterus for pregnancy by causing the uterus lining (endometrium) to thicken. This increases the chance of a successful pregnancy. You should use the medicine as prescribed for it to be effective. You may be asked to continue with this treatment for a period after becoming pregnant.show moreshow less

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Urinary incontinence

Joint pain

Vaginal discharge

Hot flushes

Breast tenderness

Depression

Headache

Dizziness

Abdominal pain

Abdominal bloating

Alcohol:CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with E Gest 300mg Tablet SR. Please consult your doctor.

Pregnancy:SAFE IF PRESCRIBED

E Gest 300mg Tablet SR is safe to use during pregnancy. Most studies have shown low or no risk to the developing baby.

Breast feeding:SAFE IF PRESCRIBED

E Gest 300mg Tablet SR is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.

Driving:UNSAFE

E Gest 300mg Tablet SR may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney:CONSULT YOUR DOCTOR

There is limited information available on the use of E Gest 300mg Tablet SR in patients with kidney disease. Please consult your doctor.

Liver:CONSULT YOUR DOCTOR

There is limited information available on the use of E Gest 300mg Tablet SR in patients with liver disease. Please consult your doctor.Use of E Gest 300mg Tablet SR is however not recommended in patients with severe liver disease.

Chrousos GP. The Gonadal Hormones & Inhibitors. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 706-707.

Levin ER, Hammes SR. Estrogens and Progestins. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1180-85.

Mayo Clinic. Progesterone. view

Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr . 2004;80:S189-S198. view

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